KEGG   PATHWAY: enb00230
Entry
enb00230                    Pathway                                
Name
Purine metabolism - Enterobacter sp. N18-03635
Class
Metabolism; Nucleotide metabolism
Pathway map
enb00230  Purine metabolism
enb00230

Module
enb_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:enb00230]
enb_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:enb00230]
enb_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:enb00230]
enb_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:enb00230]
enb_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:enb00230]
Other DBs
GO: 0006163 0042278
Organism
Enterobacter sp. N18-03635 [GN:enb]
Gene
ELK40_19405  ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ELK40_20975  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
ELK40_03850  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ELK40_06830  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
ELK40_13355  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ELK40_16015  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ELK40_01885  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ELK40_16705  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ELK40_13935  formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
ELK40_17025  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ELK40_16700  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ELK40_05930  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
ELK40_05935  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ELK40_16620  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ELK40_09130  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ELK40_01890  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ELK40_05795  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ELK40_05845  bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ELK40_18245  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ELK40_06765  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
ELK40_20990  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
ELK40_05830  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
ELK40_03855  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ELK40_05320  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ELK40_17215  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ELK40_04490  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ELK40_16810  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
ELK40_16875  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ELK40_03910  non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
ELK40_19050  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
ELK40_05010  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ELK40_15290  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
ELK40_16805  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
ELK40_04370  GMP reductase [KO:K00364] [EC:1.7.1.7]
ELK40_08390  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ELK40_01145  guanylate kinase [KO:K00942] [EC:2.7.4.8]
ELK40_15710  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
ELK40_17855  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
ELK40_15715  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ELK40_17860  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ELK40_03120  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ELK40_04625  dGTPase [KO:K01129] [EC:3.1.5.1]
ELK40_15885  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
ELK40_01135  guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ELK40_16715  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ELK40_21875  guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ELK40_18380  GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
ELK40_21750  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ELK40_02830  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ELK40_10040  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ELK40_14705  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
ELK40_18445  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ELK40_02960  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ELK40_05820  adenylate kinase [KO:K00939] [EC:2.7.4.3]
ELK40_18375  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ELK40_19395  3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ELK40_04100  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
ELK40_18280  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
ELK40_18285  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
ELK40_18290  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
ELK40_08375  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
ELK40_08385  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ELK40_01005  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ELK40_08380  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
ELK40_08405  allantoin racemase [KO:K16841] [EC:5.1.99.3]
ELK40_08410  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
ELK40_08465  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
ELK40_08460  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
ELK40_19515  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ELK40_19510  urease subunit beta [KO:K01429] [EC:3.5.1.5]
ELK40_19505  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
ELK40_08420  AtzE family amidohydrolase [KO:K22601] [EC:2.1.3.5]
ELK40_08430  oxamate amidohydrolase [KO:K22602] [EC:3.5.1.126]
ELK40_17775  carbamate kinase family protein [KO:K00926] [EC:2.7.2.2]
ELK40_03190  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
enb00030  Pentose phosphate pathway
enb00220  Arginine biosynthesis
enb00250  Alanine, aspartate and glutamate metabolism
enb00260  Glycine, serine and threonine metabolism
enb00340  Histidine metabolism
enb00630  Glyoxylate and dicarboxylate metabolism
enb00730  Thiamine metabolism
enb00740  Riboflavin metabolism
enb00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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