KEGG   PATHWAY: fca00330
Entry
fca00330                    Pathway                                
Name
Arginine and proline metabolism - Felis catus (domestic cat)
Class
Metabolism; Amino acid metabolism
Pathway map
fca00330  Arginine and proline metabolism
fca00330

Module
fca_M00015  Proline biosynthesis, glutamate => proline [PATH:fca00330]
fca_M00047  Creatine pathway [PATH:fca00330]
fca_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:fca00330]
fca_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:fca00330]
fca_M00970  Proline degradation, proline => glutamate [PATH:fca00330]
fca_M00972  Proline metabolism [PATH:fca00330]
Other DBs
GO: 0006525 0006560
Organism
Felis catus (domestic cat) [GN:fca]
Gene
101080506  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
101080661  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
101081160  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
101081650  AZIN2; antizyme inhibitor 2 [KO:K01583] [EC:4.1.1.19]
101081838  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
101082028  ALDH16A1; aldehyde dehydrogenase family 16 member A1 isoform X1 [KO:K00128] [EC:1.2.1.3]
101082267  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
101083692  AGMAT; agmatinase, mitochondrial [KO:K27001]
101084109  AMD1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
101084867  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
101085155  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
101086280  PYCR2; pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
101086559  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
101086623  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
101087020  NOS2; nitric oxide synthase, inducible isoform X2 [KO:K13241] [EC:1.14.13.39]
101087368  PRODH2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
101087429  DAO; D-amino-acid oxidase isoform X3 [KO:K00273] [EC:1.4.3.3]
101087473  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
101088213  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
101088322  [KO:K00657] [EC:2.3.1.57]
101089025  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
101089865  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
101090160  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
101090490  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X2 [KO:K00286] [EC:1.5.1.2]
101090664  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
101090803  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X2 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
101090842  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
101091848  MAOA; amine oxidase [flavin-containing] A isoform X1 [KO:K00274] [EC:1.4.3.4]
101092086  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
101092944  ARG2; arginase-2, mitochondrial isoform X1 [KO:K01476] [EC:3.5.3.1]
101093752  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
101094394  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
101095774  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
101095936  CKM; creatine kinase M-type [KO:K27382]
101096221  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
101096463  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
101096617  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X3 [KO:K00128] [EC:1.2.1.3]
101096703  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
101096846  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
101097498  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
101097983  CKMT1B; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
101098237  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
101098404  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
101098960  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
101099254  SAT2; thialysine N-epsilon-acetyltransferase isoform X1 [KO:K00657] [EC:2.3.1.57]
101099457  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
101099503  CNDP1; beta-Ala-His dipeptidase isoform X1 [KO:K05604] [EC:3.4.13.20]
101100342  NOS1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
101100421  [KO:K00318] [EC:1.5.5.2]
101101148  [KO:K01581] [EC:4.1.1.17]
101101417  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X2 [KO:K18123] [EC:4.1.3.16]
414734  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
fca00020  Citrate cycle (TCA cycle)
fca00220  Arginine biosynthesis
fca00250  Alanine, aspartate and glutamate metabolism
fca00260  Glycine, serine and threonine metabolism
fca00270  Cysteine and methionine metabolism
fca00310  Lysine degradation
fca00410  beta-Alanine metabolism
fca00470  D-Amino acid metabolism
fca00480  Glutathione metabolism
fca00630  Glyoxylate and dicarboxylate metabolism
fca00650  Butanoate metabolism
fca00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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