KEGG   PATHWAY: gpo00230
Entry
gpo00230                    Pathway                                
Name
Purine metabolism - Gordonia polyisoprenivorans
Class
Metabolism; Nucleotide metabolism
Pathway map
gpo00230  Purine metabolism
gpo00230

Module
gpo_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:gpo00230]
gpo_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:gpo00230]
gpo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:gpo00230]
gpo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:gpo00230]
gpo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:gpo00230]
Other DBs
GO: 0006163 0042278
Organism
Gordonia polyisoprenivorans [GN:gpo]
Gene
GPOL_c32500  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
GPOL_c13730  prs; ribose-phosphate pyrophosphokinase Prs [KO:K00948] [EC:2.7.6.1]
GPOL_c40770  purF; amidophosphoribosyltransferase PurF [KO:K00764] [EC:2.4.2.14]
GPOL_c42190  purD; phosphoribosylamine--glycine ligase PurD [KO:K01945] [EC:6.3.4.13]
GPOL_c12050  purN; phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
GPOL_c43610  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
GPOL_c40870  purL; phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
GPOL_c42010  purS; phosphoribosylformylglycinamidine synthase, PurS subunit PurS [KO:K23264] [EC:6.3.5.3]
GPOL_c42000  purQ; phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
GPOL_c40760  purM; phosphoribosylformylglycinamidine cyclo-ligase PurM [KO:K01933] [EC:6.3.3.1]
GPOL_c17370  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit PurK [KO:K01589] [EC:6.3.4.18]
GPOL_c17380  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit PurE [KO:K01588] [EC:5.4.99.18]
GPOL_c42080  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase PurC [KO:K01923] [EC:6.3.2.6]
GPOL_c42100  purB; adenylosuccinate lyase PurB [KO:K01756] [EC:4.3.2.2]
GPOL_c12060  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
GPOL_c22120  apt; adenine phosphoribosyltransferase Apt [KO:K00759] [EC:2.4.2.7]
GPOL_c00670  surE; multifunctional protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
GPOL_c08010  HAD-superfamily hydrolase, subfamily IIA [KO:K02566] [EC:3.1.3.5]
GPOL_c16760  punA; purine nucleoside phosphorylase PunA [KO:K03783] [EC:2.4.2.1]
GPOL_c27700  multi-copper polyphenol oxidoreductase laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
GPOL_c23670  putative nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
GPOL_c43360  hpt; hypoxanthine-guanine phosphoribosyltransferase Hpt [KO:K00760] [EC:2.4.2.8]
GPOL_c16060  guaB; inosine-5'-monophosphate dehydrogenase GuaB [KO:K00088] [EC:1.1.1.205]
GPOL_c16070  putative IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
GPOL_c19580  ndk; nucleoside diphosphate kinase Ndk [KO:K00940] [EC:2.7.4.6]
GPOL_c18670  nucleoside-triphosphatase [KO:K01519] [EC:3.6.1.66]
GPOL_c16980  putative molybdopterin dehydrogenase, FAD-binding subunit [KO:K13479] [EC:1.17.1.4]
GPOL_c16120  guaA; GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
GPOL_c16580  putative glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
GPOL_174p00840  guaB; inosine-5'-monophosphate dehydrogenase GuaB [KO:K26110] [EC:1.7.1.7]
GPOL_c06590  guaD; guanine deaminase GuaD [KO:K01487] [EC:3.5.4.3]
GPOL_c22520  gmk; guanylate kinase Gmk [KO:K00942] [EC:2.7.4.8]
GPOL_c30860  nrdE; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
GPOL_c30840  nrdF2; ribonucleoside-diphosphate reductase subunit beta NrdF2 [KO:K00526] [EC:1.17.4.1]
GPOL_c05540  ribonucleotide reductase small subunit-like protein [KO:K00526] [EC:1.17.4.1]
GPOL_c29160  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein Dgt [KO:K01129] [EC:3.1.5.1]
GPOL_c22140  relA; GTP pyrophosphokinase RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
GPOL_c10320  putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GPOL_c14290  putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GPOL_c07610  putative adenylyl cyclase [KO:K01768] [EC:4.6.1.1]
GPOL_c05440  putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
GPOL_c24230  putative adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
GPOL_c39990  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
GPOL_c43720  purA2; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
GPOL_c32380  purA1; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
GPOL_c28230  adoK; adenosine kinase AdoK [KO:K00856] [EC:2.7.1.20]
GPOL_c16690  add2; adenosine deaminase Add [KO:K01488] [EC:3.5.4.4]
GPOL_c00910  add1; adenosine deaminase Add [KO:K21053] [EC:3.5.4.2]
GPOL_c35400  adk; adenylate kinase Adk [KO:K00939] [EC:2.7.4.3]
GPOL_c14040  putative nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
GPOL_c05140  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
GPOL_c38000  putative metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
GPOL_c21920  AP-4-A phosphorylase [KO:K19710] [EC:2.7.7.53]
GPOL_c40910  cysNC3; bifunctional enzyme CysN/CysC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
GPOL_c14190  cysNC1; bifunctional enzyme CysN/CysC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
GPOL_c29450  cysNC2; bifunctional enzyme CysN/CysC [KO:K00956] [EC:2.7.7.4]
GPOL_c40920  cysD3; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
GPOL_c29440  cysD2; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
GPOL_c14180  cysD1; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
GPOL_c30910  6-hydroxynicotinate 3-monooxygenase [KO:K16839] [EC:1.14.13.113]
GPOL_c17180  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
GPOL_c17190  putative OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
GPOL_c36320  putative hydantoin racemase [KO:K16841] [EC:5.1.99.3]
GPOL_c20160  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
GPOL_c43440  alc; allantoicase Alc [KO:K01477] [EC:3.5.3.4]
GPOL_174p00920  ureC; urease subunit alpha UreC [KO:K01428] [EC:3.5.1.5]
GPOL_174p00910  ureB; urease subunit beta UreB [KO:K01429] [EC:3.5.1.5]
GPOL_174p00900  ureA; urease subunit gamma UreA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
gpo00030  Pentose phosphate pathway
gpo00220  Arginine biosynthesis
gpo00250  Alanine, aspartate and glutamate metabolism
gpo00260  Glycine, serine and threonine metabolism
gpo00340  Histidine metabolism
gpo00630  Glyoxylate and dicarboxylate metabolism
gpo00730  Thiamine metabolism
gpo00740  Riboflavin metabolism
gpo00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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