KEGG   PATHWAY: hgl00190
Entry
hgl00190                    Pathway                                
Name
Oxidative phosphorylation - Heterocephalus glaber (naked mole-rat)
Class
Metabolism; Energy metabolism
Pathway map
hgl00190  Oxidative phosphorylation
hgl00190

Module
hgl_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:hgl00190]
hgl_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:hgl00190]
hgl_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:hgl00190]
hgl_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:hgl00190]
hgl_M00148  Succinate dehydrogenase (ubiquinone) [PATH:hgl00190]
hgl_M00151  Cytochrome bc1 complex respiratory unit [PATH:hgl00190]
hgl_M00152  Cytochrome bc1 complex [PATH:hgl00190]
hgl_M00154  Cytochrome c oxidase [PATH:hgl00190]
hgl_M00158  F-type ATPase, eukaryotes [PATH:hgl00190]
hgl_M00160  V-type ATPase, eukaryotes [PATH:hgl00190]
Organism
Heterocephalus glaber (naked mole-rat) [GN:hgl]
Gene
10201222  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
10201215  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
10201214  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
10201219  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
10201217  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
10201218  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
10201220  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
101698993  Ndufs1; NADH:ubiquinone oxidoreductase core subunit S1 [KO:K03934] [EC:7.1.1.2]
101701670  Ndufs2; NADH:ubiquinone oxidoreductase core subunit S2 [KO:K03935] [EC:7.1.1.2]
101699222  Ndufs3; NADH:ubiquinone oxidoreductase core subunit S3 [KO:K03936] [EC:7.1.1.2]
101699557  Ndufs4; NADH:ubiquinone oxidoreductase subunit S4 [KO:K03937]
101709385  Ndufs5; NADH:ubiquinone oxidoreductase subunit S5 [KO:K03938]
101710541  Ndufs6; NADH:ubiquinone oxidoreductase subunit S6 [KO:K03939]
101702397  Ndufs7; NADH:ubiquinone oxidoreductase core subunit S7 [KO:K03940] [EC:7.1.1.2]
101721961  Ndufs8; NADH:ubiquinone oxidoreductase core subunit S8 [KO:K03941] [EC:7.1.1.2]
101726275  Ndufv1; NADH:ubiquinone oxidoreductase core subunit V1 [KO:K03942] [EC:7.1.1.2]
101710102  Ndufv2; NADH:ubiquinone oxidoreductase core subunit V2 [KO:K03943] [EC:7.1.1.2]
101706205  Ndufv3; NADH:ubiquinone oxidoreductase subunit V3 [KO:K03944]
106010407  Ndufa1; NADH:ubiquinone oxidoreductase subunit A1 [KO:K03945]
101709230  Ndufa2; NADH:ubiquinone oxidoreductase subunit A2 [KO:K03946]
101696601  Ndufa3; NADH:ubiquinone oxidoreductase subunit A3 [KO:K03947]
101721074  Ndufa4l2; NDUFA4, mitochondrial complex associated like 2 [KO:K03948]
101706227  Ndufa4; NDUFA4, mitochondrial complex associated [KO:K03948]
101701548  Ndufa5; NADH:ubiquinone oxidoreductase subunit A5 [KO:K03949]
101725381  Ndufa6; NADH:ubiquinone oxidoreductase subunit A6 [KO:K03950]
101716235  Ndufa7; NADH:ubiquinone oxidoreductase subunit A7 [KO:K03951]
101703248  Ndufa8; NADH:ubiquinone oxidoreductase subunit A8 [KO:K03952]
101725535  Ndufa9; NADH:ubiquinone oxidoreductase subunit A9 [KO:K03953]
101698851  Ndufa10; NADH:ubiquinone oxidoreductase subunit A10 [KO:K03954]
101719526  Ndufab1; NADH:ubiquinone oxidoreductase subunit AB1 [KO:K03955]
101704533  Ndufa11; NADH:ubiquinone oxidoreductase subunit A11 [KO:K03956]
101710903  Ndufa12; NADH:ubiquinone oxidoreductase subunit A12 [KO:K11352]
101721624  Ndufa13; NADH:ubiquinone oxidoreductase subunit A13 [KO:K11353]
101726682  Ndufb1; NADH:ubiquinone oxidoreductase subunit B1 [KO:K03957]
101702077  Ndufb2; NADH:ubiquinone oxidoreductase subunit B2 [KO:K03958]
101707439  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like [KO:K03959]
101715109  Ndufb3; NADH:ubiquinone oxidoreductase subunit B3 [KO:K03959]
101696660  Ndufb4; NADH:ubiquinone oxidoreductase subunit B4 [KO:K03960]
101716995  Ndufb5; NADH:ubiquinone oxidoreductase subunit B5 [KO:K03961]
101717801  Ndufb6; NADH:ubiquinone oxidoreductase subunit B6 [KO:K03962]
101716634  Ndufb7; NADH:ubiquinone oxidoreductase subunit B7 [KO:K03963]
101715438  Ndufb8; NADH:ubiquinone oxidoreductase subunit B8 [KO:K03964]
101713987  Ndufb9; NADH:ubiquinone oxidoreductase subunit B9 [KO:K03965]
101723731  Ndufb10; NADH:ubiquinone oxidoreductase subunit B10 [KO:K03966]
101715592  Ndufb11; NADH:ubiquinone oxidoreductase subunit B11 [KO:K11351]
101714309  Ndufc1; NADH:ubiquinone oxidoreductase subunit C1 [KO:K03967]
101717191  Ndufc2; NADH:ubiquinone oxidoreductase subunit C2 [KO:K03968]
101697591  Sdha; succinate dehydrogenase complex flavoprotein subunit A [KO:K00234] [EC:1.3.5.1]
101720891  Sdhb; succinate dehydrogenase complex iron sulfur subunit B [KO:K00235] [EC:1.3.5.1]
101698043  Sdhc; succinate dehydrogenase complex subunit C [KO:K00236]
101702014  Sdhd; succinate dehydrogenase complex subunit D [KO:K00237]
101708594  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
10201221  CYTB; cytochrome b [KO:K00412]
101700825  cytochrome c1, heme protein, mitochondrial [KO:K00413]
101719627  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
101707508  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
101718708  cytochrome b-c1 complex subunit 6, mitochondrial [KO:K00416]
101707358  cytochrome b-c1 complex subunit 7 [KO:K00417]
101718608  cytochrome b-c1 complex subunit 7 [KO:K00417]
101712532  cytochrome b-c1 complex subunit 8 [KO:K00418]
101708617  cytochrome b-c1 complex subunit 9 [KO:K00419]
101726493  cytochrome b-c1 complex subunit 10 [KO:K00420]
101726271  protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
10201210  COX3; cytochrome c oxidase subunit III [KO:K02262]
10201216  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
10201212  COX2; cytochrome c oxidase subunit II [KO:K02261]
101705610  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
101714003  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
101714403  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
101714602  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
101698437  cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
101720122  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
101697786  cytochrome c oxidase subunit 6B1 [KO:K02267]
101706975  cytochrome c oxidase subunit 6B2 [KO:K02267]
101718512  cytochrome c oxidase subunit 6C-like [KO:K02268]
101708302  cytochrome c oxidase subunit 6C-like [KO:K02268]
101716380  cytochrome c oxidase subunit 6C [KO:K02268]
101699151  cytochrome c oxidase subunit 6C-like [KO:K02268]
101716432  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
101723434  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
101715151  cytochrome c oxidase subunit 7A1, mitochondrial [KO:K02270]
106010133  cytochrome c oxidase subunit 7B, mitochondrial-like [KO:K02271]
101719726  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
101722775  cytochrome c oxidase subunit 7B, mitochondrial-like [KO:K02271]
101715696  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
101713193  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
101706868  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
101696752  cytochrome c oxidase subunit 8B, mitochondrial [KO:K02273]
101700350  cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
101715399  cytochrome c oxidase assembly protein COX15 homolog [KO:K02259] [EC:1.17.99.9]
101702679  cytochrome c oxidase copper chaperone [KO:K02260]
101697060  cytochrome c-like [KO:K08738]
101700356  cytochrome c, somatic [KO:K08738]
101723798  cytochrome c-like [KO:K08738]
101704956  cytochrome c [KO:K08738]
101718508  cytochrome c, somatic [KO:K08738]
101704529  cytochrome c-like [KO:K08738]
101724567  cytochrome c, somatic [KO:K08738]
101721536  cytochrome c-like [KO:K08738]
101698192  cytochrome c, somatic [KO:K08738]
101706454  cytochrome c [KO:K08738]
101711005  cytochrome c, somatic [KO:K08738]
101713105  cytochrome c [KO:K08738]
101705806  Atp5a1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle [KO:K02132]
101701683  Atp5b; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide [KO:K02133] [EC:7.1.2.2]
101696648  Atp5c1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 [KO:K02136]
101706462  Atp5d; ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit [KO:K02134]
101720946  Atp5e; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit [KO:K02135]
101724676  ATP synthase subunit epsilon-like protein, mitochondrial [KO:K02135]
101700501  Atp5o; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit [KO:K02137]
10201211  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
101696522  Atp5f1; ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1 [KO:K02127]
101705180  Atp5g2; ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) [KO:K02128]
101717922  Atp5g3; ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) [KO:K02128]
101715991  Atp5g1; ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9) [KO:K02128]
101706195  Atp5h; ATP synthase, H+ transporting, mitochondrial Fo complex subunit D [KO:K02138]
101704437  Atp5i; ATP synthase, H+ transporting, mitochondrial Fo complex subunit E [KO:K02129]
106007574  Atp5j2; ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 [KO:K02130]
101708211  ATP synthase subunit f, mitochondrial [KO:K02130]
101702202  ATP synthase subunit f, mitochondrial [KO:K02130]
101713385  Atp5l; ATP synthase, H+ transporting, mitochondrial Fo complex subunit G [KO:K02140]
101723785  Atp5j; ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6 [KO:K02131]
10201213  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
101717344  Atp6v1a; ATPase H+ transporting V1 subunit A [KO:K02145] [EC:7.1.2.2]
101720999  Atp6v1b1; ATPase H+ transporting V1 subunit B1 [KO:K02147]
101704199  Atp6v1b2; ATPase H+ transporting V1 subunit B2 [KO:K02147]
101721955  Atp6v1c1; ATPase H+ transporting V1 subunit C1 [KO:K02148]
101726403  Atp6v1c2; ATPase H+ transporting V1 subunit C2 [KO:K02148]
101723759  Atp6v1d; ATPase H+ transporting V1 subunit D [KO:K02149]
101713169  Atp6v1e1; ATPase H+ transporting V1 subunit E1 [KO:K02150]
101715155  Atp6v1e2; ATPase H+ transporting V1 subunit E2 [KO:K02150]
101714218  Atp6v1f; ATPase H+ transporting V1 subunit F [KO:K02151]
101720978  Atp6v1g2; ATPase H+ transporting V1 subunit G2 [KO:K02152]
101722194  Atp6v1g1; ATPase H+ transporting V1 subunit G1 [KO:K02152]
101710875  Atp6v1g3; ATPase H+ transporting V1 subunit G3 [KO:K02152]
101710987  Atp6v1h; ATPase H+ transporting V1 subunit H [KO:K02144]
101700877  Atp6v0a2; ATPase H+ transporting V0 subunit a2 [KO:K02154]
101719254  Atp6v0a4; ATPase H+ transporting V0 subunit a4 [KO:K02154]
101720677  Tcirg1; T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3 [KO:K02154]
101718747  Atp6v0a1; ATPase H+ transporting V0 subunit a1 [KO:K02154]
101700782  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
101709243  Atp6v0c; ATPase H+ transporting V0 subunit c [KO:K02155]
101718458  Atp6v0b; ATPase H+ transporting V0 subunit b [KO:K03661]
101711869  Atp6v0d1; ATPase H+ transporting V0 subunit d1 [KO:K02146]
101696829  Atp6v0d2; ATPase H+ transporting V0 subunit d2 [KO:K02146]
101726308  Atp6v0e1; ATPase H+ transporting V0 subunit e1 [KO:K02153]
101723774  Atp6v0e2; ATPase H+ transporting V0 subunit e2 [KO:K02153]
101705200  Atp6ap1; ATPase H+ transporting accessory protein 1 [KO:K03662]
101724247  Atp4a; ATPase H+/K+ transporting alpha subunit [KO:K01542] [EC:7.2.2.19]
101697924  Atp4b; ATPase H+/K+ transporting beta subunit [KO:K01543] [EC:7.2.2.19]
101711071  Atp12a; ATPase H+/K+ transporting non-gastric alpha2 subunit [KO:K01544] [EC:7.2.2.19]
101714267  Ppa1; pyrophosphatase (inorganic) 1 [KO:K01507] [EC:3.6.1.1]
101708993  Ppa2; pyrophosphatase (inorganic) 2 [KO:K01507] [EC:3.6.1.1]
101723766  Lhpp; phospholysine phosphohistidine inorganic pyrophosphate phosphatase [KO:K11725] [EC:3.6.1.1 3.1.3.-]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
PMID:16469879
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
PMID:16584177
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   
LinkDB

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