KEGG   PATHWAY: jan00630
Entry
jan00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Jannaschia sp. CCS1
Class
Metabolism; Carbohydrate metabolism
Pathway map
jan00630  Glyoxylate and dicarboxylate metabolism
jan00630

Module
jan_M00373  Ethylmalonyl pathway [PATH:jan00630]
jan_M00621  Glycine cleavage system [PATH:jan00630]
jan_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:jan00630]
Other DBs
GO: 0046487 0043648
Organism
Jannaschia sp. CCS1 [GN:jan]
Gene
Jann_3703  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Jann_3285  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Jann_1845  Malate synthase [KO:K01638] [EC:2.3.3.9]
Jann_0818  malate dehydrogenase (NAD) [KO:K00024] [EC:1.1.1.37]
Jann_1841  citrate synthase [KO:K01647] [EC:2.3.3.1]
Jann_2646  aconitase [KO:K01681] [EC:4.2.1.3]
Jann_0262  Acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Jann_0493  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Jann_4050  Acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Jann_2975  Acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Jann_0668  Thiolase [KO:K00626] [EC:2.3.1.9]
Jann_0492  Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Jann_3364  MaoC-like dehydratase [KO:K17865] [EC:4.2.1.55]
Jann_0793  Crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
Jann_3164  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Jann_4118  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Jann_0797  methylmalonyl-CoA mutase [KO:K14447] [EC:5.4.99.63]
Jann_0530  Acyl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
Jann_0813  L-erythro-3-methylmalyl-CoA dehydratase [KO:K14449] [EC:4.2.1.148]
Jann_0471  Citrate lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Jann_0816  Citryl-CoA lyase [KO:K14451] [EC:3.1.2.30]
Jann_3370  biotin carboxyl carrier protein / biotin carboxylase [KO:K01965] [EC:6.4.1.3]
Jann_3374  propionyl-CoA carboxylase carboxyltransferase subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Jann_3367  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Jann_0690  FAD linked oxidase-like protein [KO:K00104] [EC:1.1.99.14]
Jann_0691  FAD linked oxidase-like protein [KO:K11472] [EC:1.1.99.14]
Jann_0693  protein of unknown function DUF224 [KO:K11473] [EC:1.1.99.14]
Jann_0915  Glycolate reductase [KO:K00015] [EC:1.1.1.26]
Jann_3650  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Jann_3129  HAD-superfamily hydrolase subfamily IA variant 1 [KO:K01091] [EC:3.1.3.18]
Jann_3184  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Jann_1973  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Jann_0734  HAD-superfamily hydrolase subfamily IA variant 3 [KO:K01091] [EC:3.1.3.18]
Jann_0625  HAD-superfamily hydrolase subfamily IA variant 3 [KO:K01091] [EC:3.1.3.18]
Jann_1162  aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Jann_2602  serine-glyoxylate aminotransferase apoenzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Jann_3472  aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Jann_1515  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Jann_1125  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Jann_1127  glutamate--putrescine ligase [KO:K01915] [EC:6.3.1.2]
Jann_1446  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Jann_2918  glutamine synthetase protein [KO:K01915] [EC:6.3.1.2]
Jann_2991  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Jann_2079  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Jann_3622  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
Jann_3620  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Jann_1720  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Jann_0837  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Jann_3621  glycine cleavage system H protein [KO:K02437]
Jann_3926  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Jann_3970  fumarase alpha subunit [KO:K03779] [EC:4.2.1.32]
Jann_3971  Fe-S type hydro-lyases tartrate/fumarate beta protein [KO:K03780] [EC:4.2.1.32]
Jann_1954  2-keto-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Jann_2556  formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
Jann_2558  formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
Jann_2559  formate dehydrogenase beta subunit [KO:K00124]
Jann_2560  formate dehydrogenase gamma subunit [KO:K00127]
Jann_0258  hypothetical protein [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
jan00010  Glycolysis / Gluconeogenesis
jan00020  Citrate cycle (TCA cycle)
jan00030  Pentose phosphate pathway
jan00053  Ascorbate and aldarate metabolism
jan00071  Fatty acid degradation
jan00230  Purine metabolism
jan00250  Alanine, aspartate and glutamate metabolism
jan00260  Glycine, serine and threonine metabolism
jan00620  Pyruvate metabolism
jan00710  Carbon fixation by Calvin cycle
jan00750  Vitamin B6 metabolism
jan00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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