KEGG   PATHWAY: klu00230
Entry
klu00230                    Pathway                                
Name
Purine metabolism - Kluyvera sp. CRP
Class
Metabolism; Nucleotide metabolism
Pathway map
klu00230  Purine metabolism
klu00230

Module
klu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:klu00230]
klu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:klu00230]
klu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:klu00230]
klu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:klu00230]
klu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:klu00230]
Other DBs
GO: 0006163 0042278
Organism
Kluyvera sp. CRP [GN:klu]
Gene
K7B04_08620  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
K7B04_07080  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
K7B04_01670  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
K7B04_12325  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
K7B04_18620  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
K7B04_22290  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
K7B04_03560  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
K7B04_23080  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
K7B04_19630  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
K7B04_23440  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
K7B04_23075  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
K7B04_11680  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
K7B04_11685  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
K7B04_22925  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
K7B04_14845  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
K7B04_03555  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
K7B04_11525  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
K7B04_11575  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
K7B04_10050  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
K7B04_13825  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
K7B04_12260  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
K7B04_07070  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
K7B04_11560  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
K7B04_11715  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
K7B04_01665  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
K7B04_10905  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
K7B04_23640  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K7B04_16725  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
K7B04_00785  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
K7B04_23130  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
K7B04_23235  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
K7B04_01555  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
K7B04_08985  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
K7B04_00210  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
K7B04_22795  type 1 glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
K7B04_23125  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
K7B04_00900  GMP reductase [KO:K00364] [EC:1.7.1.7]
K7B04_18980  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
K7B04_06015  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
K7B04_21805  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
K7B04_21810  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
K7B04_02335  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
K7B04_00610  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
K7B04_22145  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
K7B04_06005  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
K7B04_04115  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K7B04_23090  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
K7B04_09930  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
K7B04_03980  cyaA; class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
K7B04_02725  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
K7B04_16720  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
K7B04_20780  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
K7B04_09880  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
K7B04_21235  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
K7B04_02540  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
K7B04_06760  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
K7B04_11550  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
K7B04_09935  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
K7B04_08630  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
K7B04_01200  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH [KO:K01525] [EC:3.6.1.41]
K7B04_10020  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
K7B04_10015  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
K7B04_10010  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
K7B04_19000  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
K7B04_18985  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
K7B04_19580  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
K7B04_18990  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
K7B04_18965  hpxA; allantoin racemase [KO:K16841] [EC:5.1.99.3]
K7B04_18960  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
K7B04_18910  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
K7B04_18915  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
K7B04_18950  AtzE family amidohydrolase [KO:K22601] [EC:2.1.3.5]
K7B04_17575  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
klu00030  Pentose phosphate pathway
klu00220  Arginine biosynthesis
klu00250  Alanine, aspartate and glutamate metabolism
klu00260  Glycine, serine and threonine metabolism
klu00340  Histidine metabolism
klu00630  Glyoxylate and dicarboxylate metabolism
klu00730  Thiamine metabolism
klu00740  Riboflavin metabolism
klu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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