KEGG   PATHWAY: kpw00230
Entry
kpw00230                    Pathway                                
Name
Purine metabolism - Klebsiella pneumoniae subsp. pneumoniae KPNIH30
Class
Metabolism; Nucleotide metabolism
Pathway map
kpw00230  Purine metabolism
kpw00230

Module
kpw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:kpw00230]
kpw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:kpw00230]
kpw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:kpw00230]
kpw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:kpw00230]
kpw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:kpw00230]
Other DBs
GO: 0006163 0042278
Organism
Klebsiella pneumoniae subsp. pneumoniae KPNIH30 [GN:kpw]
Gene
KPNIH30_23040  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
KPNIH30_26175  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
KPNIH30_24805  nudE; adenosine nucleotide hydrolase [KO:K08312] [EC:3.6.1.-]
KPNIH30_03720  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
KPNIH30_07950  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
KPNIH30_16450  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
KPNIH30_19045  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
KPNIH30_01250  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
KPNIH30_19695  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
KPNIH30_17135  phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
KPNIH30_19965  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
KPNIH30_19690  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
KPNIH30_06290  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
KPNIH30_06295  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
KPNIH30_19615  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
KPNIH30_10570  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
KPNIH30_01255  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
KPNIH30_06145  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
KPNIH30_06205  ushA; 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
KPNIH30_21015  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
KPNIH30_07870  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
KPNIH30_24815  nucleotidase [KO:K20881] [EC:3.1.3.-]
KPNIH30_06180  guanosine kinase [KO:K00892] [EC:2.7.1.73]
KPNIH30_03725  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
KPNIH30_05545  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
KPNIH30_15770  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
KPNIH30_20150  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
KPNIH30_04545  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
KPNIH30_19745  inosine-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
KPNIH30_19800  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
KPNIH30_03770  yjjX; inositol monophosphatase [KO:K01529] [EC:3.6.1.73]
KPNIH30_22450  nucleoside-triphosphate diphosphatase [KO:K01519] [EC:3.6.1.66]
KPNIH30_05155  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
KPNIH30_14070  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
KPNIH30_14265  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
KPNIH30_19740  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
KPNIH30_04385  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
KPNIH30_14140  guanine deaminase [KO:K01487] [EC:3.5.4.3]
KPNIH30_19200  dCMP deaminase [KO:K01487] [EC:3.5.4.3]
KPNIH30_26010  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
KPNIH30_18730  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
KPNIH30_20490  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
KPNIH30_18735  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
KPNIH30_20495  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
KPNIH30_02660  ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
KPNIH30_04775  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
KPNIH30_18935  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
KPNIH30_26020  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
KPNIH30_00690  guanosine polyphosphate pyrophosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
KPNIH30_19705  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
KPNIH30_21125  relA; (p)ppGpp synthetase [KO:K00951] [EC:2.7.6.5]
KPNIH30_00825  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
KPNIH30_02310  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
KPNIH30_14975  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
KPNIH30_17570  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
KPNIH30_21185  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
KPNIH30_18275  adenine deaminase [KO:K01486] [EC:3.5.4.2]
KPNIH30_02460  cpdB; 2', 3'-cyclic nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
KPNIH30_06170  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
KPNIH30_21120  mazG; nucleoside triphosphate hydrolase [KO:K04765] [EC:3.6.1.9]
KPNIH30_02895  3',5'-cyclic-nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
KPNIH30_23030  hypothetical protein [KO:K03651] [EC:3.1.4.53]
KPNIH30_04055  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
KPNIH30_21045  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
KPNIH30_21050  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
KPNIH30_21055  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
KPNIH30_13415  monooxygenase [KO:K16839] [EC:1.14.13.113]
KPNIH30_13430  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
KPNIH30_06685  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
KPNIH30_13425  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
KPNIH30_14125  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
KPNIH30_14120  allantoinase [KO:K16842] [EC:3.5.2.5]
KPNIH30_13945  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
KPNIH30_13950  aminotransferase V [KO:K00839] [EC:2.6.1.112]
KPNIH30_23155  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
KPNIH30_23150  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
KPNIH30_23145  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
KPNIH30_13990  amidase [KO:K22601] [EC:2.1.3.5]
KPNIH30_13980  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
kpw00030  Pentose phosphate pathway
kpw00220  Arginine biosynthesis
kpw00250  Alanine, aspartate and glutamate metabolism
kpw00260  Glycine, serine and threonine metabolism
kpw00340  Histidine metabolism
kpw00630  Glyoxylate and dicarboxylate metabolism
kpw00730  Thiamine metabolism
kpw00740  Riboflavin metabolism
kpw00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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