KEGG   PATHWAY: mcal00330
Entry
mcal00330                   Pathway                                
Name
Arginine and proline metabolism - Mus caroli (Ryukyu mouse)
Class
Metabolism; Amino acid metabolism
Pathway map
mcal00330  Arginine and proline metabolism
mcal00330

Module
mcal_M00015  Proline biosynthesis, glutamate => proline [PATH:mcal00330]
mcal_M00047  Creatine pathway [PATH:mcal00330]
mcal_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:mcal00330]
mcal_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mcal00330]
mcal_M00970  Proline degradation, proline => glutamate [PATH:mcal00330]
mcal_M00972  Proline metabolism [PATH:mcal00330]
Other DBs
GO: 0006525 0006560
Organism
Mus caroli (Ryukyu mouse) [GN:mcal]
Gene
110284514  Gatm; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
110284520  Cndp2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
110284617  Cndp1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
110285158  Aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
110285310  Hoga1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
110285643  Got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
110286079  Carns1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
110286113  Aldh18a1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
110286552  Maoa; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
110286605  Sat1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
110287084  Maob; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
110287180  Sms; spermine synthase [KO:K00802] [EC:2.5.1.22]
110290017  Ckmt1a; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
110290056  [KO:K01611] [EC:4.1.1.50]
110291593  Aldh9a1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
110292223  Azin2; antizyme inhibitor 2 [KO:K01583] [EC:4.1.1.19]
110292260  Pycr2; pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
110292407  Aldh1b1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
110292778  Srm; spermidine synthase [KO:K00797] [EC:2.5.1.16]
110293439  Agmat; agmatinase, mitochondrial [KO:K27001]
110293727  Aldh4a1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
110293736  [KO:K01581] [EC:4.1.1.17]
110293870  Aldh2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
110293897  Nos3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
110294007  Lap3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
110294416  Nos1; nitric oxide synthase, brain isoform X2 [KO:K13240] [EC:1.14.13.39]
110295014  Dao; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
110296626  [KO:K11182] [EC:1.4.3.22]
110296761  [KO:K11182] [EC:1.4.3.22]
110296945  [KO:K11182] [EC:1.4.3.22]
110297026  [KO:K11182] [EC:1.4.3.22]
110297695  Prodh2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
110297756  Aldh16a1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
110298613  P4ha3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
110298736  Ckm; creatine kinase M-type [KO:K27382]
110298858  Oat; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
110300511  Got1l1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
110300885  Got2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
110302908  P4ha1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
110303027  Arg1; arginase-1 [KO:K01476] [EC:3.5.3.1]
110303213  Gamt; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
110303517  Amd1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
110304329  Aldh3a2; fatty aldehyde dehydrogenase isoform X1 [KO:K00128] [EC:1.2.1.3]
110304621  Nos2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
110304813  P4ha2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
110305644  Sat2; diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
110305649  Pycr1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
110305903  [KO:K01611] [EC:4.1.1.50]
110306718  Arg2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
110306722  Odc1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
110306752  Ckb; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
110306956  L3hypdh; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
110308181  Ckmt2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
110310540  Pycr3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
110311315  Smox; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
110311823  Prodh; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
mcal00020  Citrate cycle (TCA cycle)
mcal00220  Arginine biosynthesis
mcal00250  Alanine, aspartate and glutamate metabolism
mcal00260  Glycine, serine and threonine metabolism
mcal00270  Cysteine and methionine metabolism
mcal00310  Lysine degradation
mcal00410  beta-Alanine metabolism
mcal00470  D-Amino acid metabolism
mcal00480  Glutathione metabolism
mcal00630  Glyoxylate and dicarboxylate metabolism
mcal00650  Butanoate metabolism
mcal00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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