KEGG   PATHWAY: metu00230
Entry
metu00230                   Pathway                                
Name
Purine metabolism - Methylococcus geothermalis
Class
Metabolism; Nucleotide metabolism
Pathway map
metu00230  Purine metabolism
metu00230

Module
metu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:metu00230]
metu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:metu00230]
metu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:metu00230]
metu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:metu00230]
metu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:metu00230]
Other DBs
GO: 0006163 0042278
Organism
Methylococcus geothermalis [GN:metu]
Gene
GNH96_09265  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
GNH96_15140  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
GNH96_00515  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
GNH96_10500  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
GNH96_12715  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
GNH96_05480  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
GNH96_01565  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
GNH96_07105  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
GNH96_06010  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
GNH96_13980  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
GNH96_15655  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
GNH96_15660  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
GNH96_02470  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
GNH96_09755  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
GNH96_10390  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
GNH96_04655  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
GNH96_03725  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
GNH96_11095  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
GNH96_05825  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
GNH96_03240  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
GNH96_11920  DUF1255 family protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
GNH96_08555  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
GNH96_07220  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
GNH96_03060  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
GNH96_03420  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
GNH96_10370  hypothetical protein [KO:K01529] [EC:3.6.1.73]
GNH96_03080  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
GNH96_03055  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
GNH96_12990  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
GNH96_03275  guanylate kinase [KO:K00942] [EC:2.7.4.8]
GNH96_08840  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
GNH96_15730  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
GNH96_08825  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
GNH96_04710  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
GNH96_07030  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
GNH96_07875  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GNH96_13420  RelA/SpoT family protein [KO:K00951] [EC:2.7.6.5]
GNH96_04860  family 3 adenylate cyclase [KO:K01768] [EC:4.6.1.1]
GNH96_05645  CYTH domain-containing protein [KO:K01768] [EC:4.6.1.1]
GNH96_15215  response regulator [KO:K01768] [EC:4.6.1.1]
GNH96_15220  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K01768] [EC:4.6.1.1]
GNH96_07255  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
GNH96_02575  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
GNH96_02265  DUF3412 domain-containing protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
GNH96_06815  adenylate kinase [KO:K00939] [EC:2.7.4.3]
GNH96_02570  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
GNH96_08030  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
GNH96_00990  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
GNH96_06360  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
GNH96_12215  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
GNH96_00265  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
GNH96_05345  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
GNH96_00270  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
metu00030  Pentose phosphate pathway
metu00220  Arginine biosynthesis
metu00250  Alanine, aspartate and glutamate metabolism
metu00260  Glycine, serine and threonine metabolism
metu00340  Histidine metabolism
metu00630  Glyoxylate and dicarboxylate metabolism
metu00730  Thiamine metabolism
metu00740  Riboflavin metabolism
metu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system