KEGG   PATHWAY: mni00330
Entry
mni00330                    Pathway                                
Name
Arginine and proline metabolism - Macaca nemestrina (pig-tailed macaque)
Class
Metabolism; Amino acid metabolism
Pathway map
mni00330  Arginine and proline metabolism
mni00330

Module
mni_M00015  Proline biosynthesis, glutamate => proline [PATH:mni00330]
mni_M00047  Creatine pathway [PATH:mni00330]
mni_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:mni00330]
mni_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:mni00330]
mni_M00970  Proline degradation, proline => glutamate [PATH:mni00330]
mni_M00972  Proline metabolism [PATH:mni00330]
Other DBs
GO: 0006525 0006560
Organism
Macaca nemestrina (pig-tailed macaque) [GN:mni]
Gene
105491008  GATM; glycine amidinotransferase, mitochondrial isoform X2 [KO:K00613] [EC:2.1.4.1]
105486165  GAMT; guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
105475061  CKMT2; creatine kinase S-type, mitochondrial isoform X1 [KO:K00933] [EC:2.7.3.2]
105489815  CKB; creatine kinase B-type isoform X2 [KO:K00933] [EC:2.7.3.2]
105491353  creatine kinase U-type, mitochondrial isoform X1 [KO:K00933] [EC:2.7.3.2]
105491385  creatine kinase U-type, mitochondrial-like isoform X1 [KO:K00933] [EC:2.7.3.2]
105478542  CKM; creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
105494663  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
105486493  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
105495210  antizyme inhibitor 2-like [KO:K01581] [EC:4.1.1.17]
105473145  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
105478217  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
105492077  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
105474898  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
105481573  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
105477178  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
105493337  ALDH3A2; fatty aldehyde dehydrogenase isoform X2 [KO:K00128] [EC:1.2.1.3]
112422914  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
105463163  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
105468632  alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
105492964  ALDH9A1; LOW QUALITY PROTEIN: 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
105489329  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
105489330  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
105469678  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
105473653  SAT2; diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
105478229  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
105463379  amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
105463385  MAOB; amine oxidase [flavin-containing] B isoform X1 [KO:K00274] [EC:1.4.3.4]
105473216  AGMAT; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
105495113  NOS1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
105476942  NOS2; LOW QUALITY PROTEIN: nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
105474900  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
105465607  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
105472868  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
105470121  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
105488452  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
105478534  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X1 [KO:K00286] [EC:1.5.1.2]
105500005  pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
105469319  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
105480741  PRODH; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
105483124  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
105478482  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
105487885  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
105466027  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
105467184  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
105468730  P4HA3; LOW QUALITY PROTEIN: prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
105495496  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
105476577  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
105478419  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
105491499  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
105478444  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
105498206  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
105473638  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
mni00020  Citrate cycle (TCA cycle)
mni00220  Arginine biosynthesis
mni00250  Alanine, aspartate and glutamate metabolism
mni00260  Glycine, serine and threonine metabolism
mni00270  Cysteine and methionine metabolism
mni00310  Lysine degradation
mni00410  beta-Alanine metabolism
mni00470  D-Amino acid metabolism
mni00480  Glutathione metabolism
mni00630  Glyoxylate and dicarboxylate metabolism
mni00650  Butanoate metabolism
mni00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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