KEGG   PATHWAY: ncar00564
Entry
ncar00564                   Pathway                                
Name
Glycerophospholipid metabolism - Sciurus carolinensis (gray squirrel)
Class
Metabolism; Lipid metabolism
Pathway map
ncar00564  Glycerophospholipid metabolism
ncar00564

Module
ncar_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:ncar00564]
ncar_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:ncar00564]
ncar_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:ncar00564]
Other DBs
GO: 0006650
Organism
Sciurus carolinensis (gray squirrel) [GN:ncar]
Gene
124969149  glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
124982025  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
124980161  glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
124985389  glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
124963230  glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
124994842  glycerol-3-phosphate acyltransferase 3 isoform X1 [KO:K13506] [EC:2.3.1.15]
124982430  glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
124988247  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
124964269  1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
124989565  1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
124992457  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
124983194  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
124963535  lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
124989677  lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
124963397  lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
124994786  LOW QUALITY PROTEIN: dihydroxyacetone phosphate acyltransferase-like [KO:K00649] [EC:2.3.1.42]
124961653  LOW QUALITY PROTEIN: dihydroxyacetone phosphate acyltransferase-like [KO:K00649] [EC:2.3.1.42]
124982828  LOW QUALITY PROTEIN: dihydroxyacetone phosphate acyltransferase-like [KO:K00649] [EC:2.3.1.42]
124979804  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
124987057  phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
124984274  phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
124975377  phospholipid phosphatase 2 isoform X1 [KO:K01080] [EC:3.1.3.4]
124977632  phosphatidate phosphatase LPIN3-like isoform X1 [KO:K15728] [EC:3.1.3.4]
124963013  phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
124965194  phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
124985178  phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
124983291  phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
124958295  diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
124992678  diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
124994443  diacylglycerol kinase theta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
124990745  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
124990880  diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
124984733  diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
124980607  diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
124980768  diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
124982033  diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
124972550  diacylglycerol kinase kappa-like [KO:K00901] [EC:2.7.1.107]
124982162  cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
124961782  choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
124992927  phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
124980798  phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
124967308  5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
124977380  5'-3' exonuclease PLD4-like isoform X1 [KO:K16860] [EC:3.1.4.4]
124967377  phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
124992670  phospholipase A2, membrane associated-like [KO:K01047] [EC:3.1.1.4]
124994826  phospholipase A2 group V-like isoform X1 [KO:K01047] [EC:3.1.1.4]
124995067  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
124990140  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
124991958  group 3 secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
124984456  group IIF secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
124984465  group IIC secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
124984498  group IID secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
124985388  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
124960500  group IIE secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
124969812  group 10 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
124976716  cytosolic phospholipase A2 beta [KO:K16342] [EC:3.1.1.4]
124976990  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
124978216  cytosolic phospholipase A2 delta-like [KO:K16342] [EC:3.1.1.4]
124978217  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
124962073  cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
124974890  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
124982638  85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
124963630  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
124960320  LOW QUALITY PROTEIN: phospholipase A and acyltransferase 2-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
124958977  phospholipase A and acyltransferase 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
124986996  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
124966766  LOW QUALITY PROTEIN: lysophosphatidylcholine acyltransferase 2-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
124977747  lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
124981991  lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
124992350  acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
124963372  LOW QUALITY PROTEIN: phospholipase A2 group XV-like [KO:K06129] [EC:3.1.1.5]
124966556  phospholipase A2 group XV isoform X1 [KO:K06129] [EC:3.1.1.5]
124985300  acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
124968665  patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
124964299  patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
124975950  glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
124985917  choline O-acetyltransferase isoform X1 [KO:K00623] [EC:2.3.1.6]
124970217  acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
124958897  choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
124983219  choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
124987104  LOW QUALITY PROTEIN: phosphoethanolamine/phosphocholine phosphatase-like [KO:K06124] [EC:3.1.3.75]
124980047  phosphoethanolamine/phosphocholine phosphatase isoform X1 [KO:K06124] [EC:3.1.3.75]
124993517  choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
124971304  LOW QUALITY PROTEIN: choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
124962995  ethanolaminephosphotransferase 1-like isoform X1 [KO:K00993] [EC:2.7.8.1]
124961649  ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
124982507  LOW QUALITY PROTEIN: ethanolamine kinase 1-like [KO:K00894] [EC:2.7.1.82]
124979689  ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
124994928  ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
124980751  LOW QUALITY PROTEIN: phosphatidylethanolamine N-methyltransferase-like [KO:K00551] [EC:2.1.1.17 2.1.1.71]
124994606  phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
124976150  LOW QUALITY PROTEIN: phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
124993116  phospholipase A1 member A-like isoform X1 [KO:K13618] [EC:3.1.1.111]
124985683  phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
124960393  phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
124991641  phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
124978922  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
124975955  cardiolipin synthase (CMP-forming) isoform X1 [KO:K08744] [EC:2.7.8.41]
124972472  tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
124961683  acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
124970688  CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
124967142  lysophospholipid acyltransferase 7 isoform X1 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
ncar00010  Glycolysis / Gluconeogenesis
ncar00260  Glycine, serine and threonine metabolism
ncar00561  Glycerolipid metabolism
ncar00562  Inositol phosphate metabolism
ncar00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
ncar00565  Ether lipid metabolism
ncar00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

DBGET integrated database retrieval system