KEGG   PATHWAY: arut00350
Entry
arut00350                   Pathway                                
Name
Tyrosine metabolism - Acipenser ruthenus (sterlet)
Class
Metabolism; Amino acid metabolism
Pathway map
arut00350  Tyrosine metabolism
arut00350

Module
arut_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:arut00350]
arut_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:arut00350]
arut_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:arut00350]
Other DBs
GO: 0006570
Organism
Acipenser ruthenus (sterlet) [GN:arut]
Gene
117968936  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
117397717  aspartate aminotransferase, cytoplasmic isoform X1 [KO:K14454] [EC:2.6.1.1]
117415887  got1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
117417651  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
117425021  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
117425437  tat; tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
117424131  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
117397368  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
117422133  L-amino-acid oxidase-like isoform X1 [KO:K03334] [EC:1.4.3.2]
117422222  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
117397171  LOW QUALITY PROTEIN: L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
117973262  4-hydroxyphenylpyruvate dioxygenase-like isoform X1 [KO:K00457] [EC:1.13.11.27]
117427663  4-hydroxyphenylpyruvate dioxygenase-like [KO:K00457] [EC:1.13.11.27]
117429876  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
117972906  homogentisate 1,2-dioxygenase-like [KO:K00451] [EC:1.13.11.5]
117405197  homogentisate 1,2-dioxygenase-like [KO:K00451] [EC:1.13.11.5]
117417315  maleylacetoacetate isomerase-like isoform X1 [KO:K01800] [EC:5.2.1.2]
117422173  maleylacetoacetate isomerase-like isoform X2 [KO:K01800] [EC:5.2.1.2]
117429856  fumarylacetoacetase-like [KO:K01555] [EC:3.7.1.2]
117428510  fumarylacetoacetase-like [KO:K01555] [EC:3.7.1.2]
117406512  tyrosinase-like [KO:K00505] [EC:1.14.18.1]
117404921  tyrosinase-like [KO:K00505] [EC:1.14.18.1]
117965811  tyrosinase-like [KO:K00505] [EC:1.14.18.1]
117405438  LOW QUALITY PROTEIN: tyrosinase [KO:K00505] [EC:1.14.18.1]
117414286  tyrosinase-like [KO:K00505] [EC:1.14.18.1]
117415781  th2; tyrosine hydroxylase 2 [KO:K00501] [EC:1.14.16.2]
117435126  tyrosine 3-monooxygenase-like [KO:K00501] [EC:1.14.16.2]
117432410  tyrosine 3-monooxygenase-like isoform X1 [KO:K00501] [EC:1.14.16.2]
117406809  dct; L-dopachrome tautomerase [KO:K01827] [EC:5.3.3.12]
117408362  5,6-dihydroxyindole-2-carboxylic acid oxidase-like [KO:K00506] [EC:1.14.18.-]
117420963  5,6-dihydroxyindole-2-carboxylic acid oxidase-like [KO:K00506] [EC:1.14.18.-]
117435476  aromatic-L-amino-acid decarboxylase-like isoform X1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
117400633  aromatic-L-amino-acid decarboxylase-like isoform X1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
117422501  dbh; LOW QUALITY PROTEIN: dopamine beta-hydroxylase [KO:K00503] [EC:1.14.17.1]
117435192  phenylethanolamine N-methyltransferase isoform X1 [KO:K00553] [EC:2.1.1.28]
117972632  transmembrane O-methyltransferase homolog isoform X1 [KO:K00545] [EC:2.1.1.6]
117426865  catechol O-methyltransferase-like [KO:K00545] [EC:2.1.1.6]
117405881  transmembrane O-methyltransferase homolog isoform X1 [KO:K00545] [EC:2.1.1.6]
117428389  catechol O-methyltransferase-like [KO:K00545] [EC:2.1.1.6]
117964623  transmembrane O-methyltransferase homolog [KO:K00545] [EC:2.1.1.6]
117401799  catechol O-methyltransferase B [KO:K00545] [EC:2.1.1.6]
117431088  transmembrane O-methyltransferase homolog [KO:K00545] [EC:2.1.1.6]
117407136  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
117430315  amine oxidase [flavin-containing] B-like [KO:K00274] [EC:1.4.3.4]
117410056  aldh3b1; aldehyde dehydrogenase family 3 member B1 [KO:K00129] [EC:1.2.1.5]
117427066  aldehyde dehydrogenase family 3 member B1-like [KO:K00129] [EC:1.2.1.5]
117427609  aldehyde dehydrogenase family 3 member B1-like [KO:K00129] [EC:1.2.1.5]
117420700  alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117962758  alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117972433  alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117408703  LOW QUALITY PROTEIN: alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117420552  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117420553  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117420756  alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117421376  alcohol dehydrogenase class-3-like isoform X2 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
117411246  tpo; thyroid peroxidase [KO:K00431] [EC:1.11.1.8]
117432329  epx; thyroid peroxidase [KO:K00431] [EC:1.11.1.8]
117402944  aox5; aldehyde oxidase 5 [KO:K00157] [EC:1.2.3.1]
117418008  fahd1; acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
117431732  acylpyruvase FAHD1, mitochondrial-like [KO:K01557] [EC:3.7.1.5]
117426147  macrophage migration inhibitory factor-like isoform X2 [KO:K07253] [EC:5.3.2.1]
117428476  macrophage migration inhibitory factor-like [KO:K07253] [EC:5.3.2.1]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
arut00020  Citrate cycle (TCA cycle)
arut00360  Phenylalanine metabolism
arut00400  Phenylalanine, tyrosine and tryptophan biosynthesis
arut00620  Pyruvate metabolism
arut00650  Butanoate metabolism
KO pathway
ko00350   
LinkDB

DBGET integrated database retrieval system