KEGG   PATHWAY: bbra00230
Entry
bbra00230                   Pathway                                
Name
Purine metabolism - Bradyrhizobium brasilense
Class
Metabolism; Nucleotide metabolism
Pathway map
bbra00230  Purine metabolism
bbra00230

Module
bbra_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bbra00230]
bbra_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bbra00230]
bbra_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bbra00230]
bbra_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bbra00230]
bbra_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bbra00230]
bbra_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bbra00230]
Other DBs
GO: 0006163 0042278
Organism
Bradyrhizobium brasilense [GN:bbra]
Gene
QA636_10475  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
QA636_03545  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
QA636_36925  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
QA636_25135  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
QA636_37180  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
QA636_24885  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
QA636_17450  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
QA636_17390  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
QA636_17400  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
QA636_24890  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
QA636_06345  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
QA636_06350  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
QA636_00080  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
QA636_17385  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
QA636_17360  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
QA636_01395  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
QA636_09580  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
QA636_32275  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
QA636_23465  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
QA636_36910  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
QA636_26085  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
QA636_24920  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
QA636_00905  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
QA636_18010  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
QA636_11065  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
QA636_32255  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
QA636_11060  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
QA636_32260  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
QA636_36720  FAD binding domain-containing protein [KO:K11178] [EC:1.17.1.4]
QA636_11055  (2Fe-2S)-binding protein [KO:K13483]
QA636_32265  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
QA636_01545  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
QA636_26005  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
QA636_25000  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
QA636_24310  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
QA636_35930  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
QA636_35925  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
QA636_23520  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
QA636_12855  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
QA636_20645  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
QA636_24910  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
QA636_26120  Ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
QA636_40820  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_06260  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_10610  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_11235  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_13690  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_17790  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_18800  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_20715  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_22755  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_23275  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_25710  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_27740  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_32335  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_36660  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QA636_07045  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
QA636_17840  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
QA636_25580  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
QA636_38425  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
QA636_38855  adenylate kinase [KO:K00939] [EC:2.7.4.3]
QA636_19385  adenylate kinase [KO:K00939] [EC:2.7.4.3]
QA636_22405  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
QA636_15130  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
QA636_34280  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
QA636_39335  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
QA636_33365  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
QA636_39330  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
QA636_33370  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
QA636_08530  FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
QA636_41245  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
QA636_20035  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
QA636_32010  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
QA636_31975  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
QA636_39545  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
QA636_39555  urease subunit beta [KO:K01429] [EC:3.5.1.5]
QA636_39560  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
QA636_08465  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bbra00030  Pentose phosphate pathway
bbra00220  Arginine biosynthesis
bbra00250  Alanine, aspartate and glutamate metabolism
bbra00260  Glycine, serine and threonine metabolism
bbra00340  Histidine metabolism
bbra00630  Glyoxylate and dicarboxylate metabolism
bbra00730  Thiamine metabolism
bbra00740  Riboflavin metabolism
bbra00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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