KEGG   PATHWAY: bph02024
Entry
bph02024                    Pathway                                
Name
Quorum sensing - Paraburkholderia phymatum
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
bph02024  Quorum sensing
bph02024

Other DBs
GO: 0009372
Organism
Paraburkholderia phymatum [GN:bph]
Gene
Bphy_1711  RNA chaperone Hfq [KO:K03666]
Bphy_1415  RNA chaperone Hfq [KO:K03666]
Bphy_4437  autoinducer synthesis protein [KO:K13060] [EC:2.3.1.184]
Bphy_4439  transcriptional regulator, LuxR family [KO:K18304]
Bphy_2698  anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
Bphy_2699  glutamine amidotransferase of anthranilate synthase [KO:K01658] [EC:4.1.3.27]
Bphy_2315  rhamnosyltransferase [KO:K12990] [EC:2.4.1.-]
Bphy_4110  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
Bphy_2510  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
Bphy_6232  histidine kinase [KO:K07645] [EC:2.7.13.3]
Bphy_6336  integral membrane sensor signal transduction histidine kinase [KO:K07645] [EC:2.7.13.3]
Bphy_1184  integral membrane sensor signal transduction histidine kinase [KO:K07645] [EC:2.7.13.3]
Bphy_1183  two component transcriptional regulator, winged helix family [KO:K07666]
Bphy_6233  two component transcriptional regulator, winged helix family [KO:K07666]
Bphy_6335  two component transcriptional regulator, winged helix family [KO:K07666]
Bphy_4639  flagellar transcriptional activator [KO:K02403]
Bphy_2979  flagellar transcriptional activator [KO:K02403]
Bphy_7083  flagellar transcriptional activator [KO:K02403]
Bphy_4638  flagellar transcriptional activator FlhC [KO:K02402]
Bphy_2978  flagellar transcriptional activator FlhC [KO:K02402]
Bphy_7082  flagellar transcriptional activator FlhC [KO:K02402]
Bphy_2053  two component transcriptional regulator, winged helix family [KO:K07667]
Bphy_6038  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_4322  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_6575  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_1501  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_6274  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_5429  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_7064  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_6624  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_0221  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_7049  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_4443  extracellular solute-binding protein, family 1 [KO:K02055]
Bphy_2382  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_5902  ABC spermidine/putrescine transporter, periplasmic ligand binding protein [KO:K02055]
Bphy_7798  extracellular solute-binding protein family 1 [KO:K02055]
Bphy_4324  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_5900  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_6036  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_6272  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_6578  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_6628  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_7052  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_2380  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_0223  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_1503  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_1502  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_7801  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_4446  binding-protein-dependent transport systems inner membrane component [KO:K02053]
Bphy_7062  binding-protein-dependent transport systems inner membrane component [KO:K02053 K02054]
Bphy_6579  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_7800  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_0222  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_7051  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_6273  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_4323  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_5901  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_6629  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_4445  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_6037  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_2381  binding-protein-dependent transport systems inner membrane component [KO:K02054]
Bphy_6582  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_2383  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_6630  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_6039  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_7063  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_4321  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_1504  ABC transporter related [KO:K02052]
Bphy_6271  ABC transporter related [KO:K02052]
Bphy_0224  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_5903  ABC transporter related [KO:K02052]
Bphy_7050  ABC transporter related [KO:K02052]
Bphy_4444  ABC transporter related [KO:K02052]
Bphy_7799  spermidine/putrescine ABC transporter ATPase subunit [KO:K02052]
Bphy_6859  Extracellular ligand-binding receptor [KO:K01999]
Bphy_0112  Extracellular ligand-binding receptor [KO:K01999]
Bphy_7652  ABC-type branched-chain amino acid transport systems periplasmic component-like protein [KO:K01999]
Bphy_5889  Extracellular ligand-binding receptor [KO:K01999]
Bphy_2237  ABC branched chain amino acid family transporter, periplasmic ligand binding protein [KO:K01999]
Bphy_3017  Extracellular ligand-binding receptor [KO:K01999]
Bphy_3043  Extracellular ligand-binding receptor [KO:K01999]
Bphy_3047  Extracellular ligand-binding receptor [KO:K01999]
Bphy_0588  Extracellular ligand-binding receptor [KO:K01999]
Bphy_4932  extracellular ligand-binding receptor [KO:K01999]
Bphy_6618  Extracellular ligand-binding receptor [KO:K01999]
Bphy_4465  Extracellular ligand-binding receptor [KO:K01999]
Bphy_2015  ABC branched chain amino acid family transporter, periplasmic ligand binding protein [KO:K01999]
Bphy_0197  Extracellular ligand-binding receptor [KO:K01999]
Bphy_6166  Extracellular ligand-binding receptor [KO:K01999]
Bphy_3654  Extracellular ligand-binding receptor [KO:K01999]
Bphy_3042  inner-membrane translocator [KO:K01997]
Bphy_3046  inner-membrane translocator [KO:K01997]
Bphy_1607  inner-membrane translocator [KO:K01997]
Bphy_0589  inner-membrane translocator [KO:K01997]
Bphy_4462  inner-membrane translocator [KO:K01997 K01998]
Bphy_3041  ABC transporter related [KO:K01995 K01998]
Bphy_1606  inner-membrane translocator [KO:K01995 K01998]
Bphy_0590  inner-membrane translocator [KO:K01998]
Bphy_3045  inner-membrane translocator [KO:K01998]
Bphy_3049  ABC transporter related [KO:K01995]
Bphy_0591  ABC transporter related [KO:K01995]
Bphy_4463  ABC transporter related [KO:K01995]
Bphy_1605  ABC transporter related [KO:K01995]
Bphy_1604  ABC transporter related [KO:K01996]
Bphy_0592  ABC transporter related [KO:K01996]
Bphy_3048  ABC transporter related [KO:K01996]
Bphy_3040  ABC transporter related [KO:K01996]
Bphy_4464  ABC transporter related [KO:K01996]
Bphy_7394  Pectate lyase/Amb allergen [KO:K01728] [EC:4.2.2.2]
Bphy_5278  Enoyl-CoA hydratase/isomerase [KO:K13816]
Bphy_5279  diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) [KO:K14051] [EC:3.1.4.52]
Bphy_2685  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_1704  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_5806  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_4871  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_0524  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_4840  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_4848  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_7005  AMP-dependent synthetase and ligase [KO:K01897] [EC:6.2.1.3]
Bphy_3354  ferric uptake regulator, Fur family [KO:K09823]
Bphy_0488  ferric uptake regulator, Fur family [KO:K09823]
Bphy_1769  transcriptional regulator, IclR family [KO:K20329]
Bphy_3240  GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
Bphy_0621  riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
Bphy_0480  RND efflux system, outer membrane lipoprotein, NodT family [KO:K18139]
Bphy_0649  RND efflux system, outer membrane lipoprotein, NodT family [KO:K18139]
Bphy_3490  RND efflux system, outer membrane lipoprotein, NodT family [KO:K18139]
Bphy_5505  RND efflux system, outer membrane lipoprotein, NodT family [KO:K18139]
Bphy_3507  RND efflux system, outer membrane lipoprotein, NodT family [KO:K18139]
Bphy_4505  extracellular solute-binding protein family 5 [KO:K15580]
Bphy_4504  Alkaline phosphatase [KO:K15581]
Bphy_4503  binding-protein-dependent transport systems inner membrane component [KO:K15582]
Bphy_4502  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K15583]
Bphy_4501  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K10823]
Bphy_0558  extracellular solute-binding protein family 5 [KO:K02035]
Bphy_6651  extracellular solute-binding protein family 5 [KO:K02035]
Bphy_4004  extracellular solute-binding protein family 5 [KO:K02035]
Bphy_6591  extracellular solute-binding protein family 5 [KO:K02035]
Bphy_7644  extracellular solute-binding protein family 5 [KO:K02035]
Bphy_0557  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Bphy_6650  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Bphy_7645  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Bphy_4005  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Bphy_6590  binding-protein-dependent transport systems inner membrane component [KO:K02033]
Bphy_0556  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Bphy_6649  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Bphy_7646  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Bphy_4006  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Bphy_6589  binding-protein-dependent transport systems inner membrane component [KO:K02034]
Bphy_7647  ABC transporter related [KO:K02031]
Bphy_4007  ABC transporter related [KO:K02031]
Bphy_6588  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02031 K02032]
Bphy_0555  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02031 K02032]
Bphy_6653  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02031]
Bphy_4008  ABC transporter related [KO:K02032]
Bphy_7648  ABC transporter related [KO:K02032]
Bphy_6652  oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K02032]
Bphy_3098  60 kDa inner membrane insertion protein [KO:K03217]
Bphy_2854  preprotein translocase, SecE subunit [KO:K03073]
Bphy_2010  preprotein translocase, SecG subunit [KO:K03075]
Bphy_2819  preprotein translocase, SecY subunit [KO:K03076]
Bphy_2526  preprotein translocase, YajC subunit [KO:K03210]
Bphy_2664  preprotein translocase, SecA subunit [KO:K03070] [EC:7.4.2.8]
Bphy_0308  signal recognition particle-docking protein FtsY [KO:K03110]
Bphy_0269  protein-export protein SecB [KO:K03071]
Bphy_2643  signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
Bphy_3755  phosphoesterase [KO:K01114] [EC:3.1.4.3]
Bphy_7067  Phospholipase C [KO:K01114] [EC:3.1.4.3]
Bphy_5529  phosphoesterase [KO:K01114] [EC:3.1.4.3]
Bphy_6939  Phospholipase C [KO:K01114] [EC:3.1.4.3]
Bphy_1546  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
Bphy_7081  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
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Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
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PMID:23799665
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Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
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Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
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Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
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PMID:21166386
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Deng Y, Wu J, Tao F, Zhang LH
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Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
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Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
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Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
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Trends Microbiol 19:145-52 (2011)
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PMID:15522077
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Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
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Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
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Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
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PMID:17376080
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Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
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Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
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Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
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PMID:21622734
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Stauff DL, Bassler BL
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Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
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J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
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PMID:21504831
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Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
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A strategy for antagonizing quorum sensing.
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Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
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Hao G, Burr TJ
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Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
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J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
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Savka MA, Le PT, Burr TJ
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LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
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Curr Microbiol 62:101-10 (2011)
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PMID:26579084
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Le KY, Otto M
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Quorum-sensing regulation in staphylococci-an overview.
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Front Microbiol 6:1174 (2015)
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PMID:18851841
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Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
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RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
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Mol Cell 32:150-8 (2008)
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Darkoh C, DuPont HL, Norris SJ, Kaplan HB
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Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
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MBio 6:e02569 (2015)
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PMID:25824838
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Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
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Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
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Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
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Virulence gene regulation by the agr system in Clostridium perfringens.
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J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
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PMID:22736963
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Li YH, Tian X
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Quorum sensing and bacterial social interactions in biofilms.
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Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
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PMID:22407687
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Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
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Properties and biological role of streptococcal fratricins.
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Appl Environ Microbiol 78:3515-22 (2012)
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Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
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Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
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J Oral Microbiol 6:26189 (2014)
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Jimenez JC, Federle MJ
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Quorum sensing in group A Streptococcus.
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Front Cell Infect Microbiol 4:127 (2014)
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Cook LC, Federle MJ
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Peptide pheromone signaling in Streptococcus and Enterococcus.
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FEMS Microbiol Rev 38:473-92 (2014)
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The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
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Mol Microbiol 28:1323-34 (1998)
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Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
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Mol Microbiol 21:1087-99 (1996)
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PMID:22636768
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Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
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Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
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J Bacteriol 194:3961-71 (2012)
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PMID:22016844
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Clewell DB
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Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
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Mob Genet Elements 1:38-54 (2011)
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PMID:20734751
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Wardal E, Sadowy E, Hryniewicz W
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Complex nature of enterococcal pheromone-responsive plasmids.
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Pol J Microbiol 59:79-87 (2010)
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PMID:19683678
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Roux A, Payne SM, Gilmore MS
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Microbial telesensing: probing the environment for friends, foes, and food.
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Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
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PMID:25089349
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Slamti L, Perchat S, Huillet E, Lereclus D
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Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
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Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
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PMID:20030732
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Lopez D, Kolter R
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Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
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FEMS Microbiol Rev 34:134-49 (2010)
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PMID:12897006
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Stephenson S, Mueller C, Jiang M, Perego M
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Molecular analysis of Phr peptide processing in Bacillus subtilis.
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J Bacteriol 185:4861-71 (2003)
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PMID:17666034
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Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
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Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
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Mol Microbiol 65:1321-33 (2007)
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PMID:15374644
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Kleerebezem M
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Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
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Peptides 25:1405-14 (2004)
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PMID:23125205
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Rutherford ST, Bassler BL
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Bacterial quorum sensing: its role in virulence and possibilities for its control.
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Cold Spring Harb Perspect Med 2:a012427 (2012)
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PMID:23471618
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LaSarre B, Federle MJ
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Exploiting quorum sensing to confuse bacterial pathogens.
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Microbiol Mol Biol Rev 77:73-111 (2013)
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PMID:18781869
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Sifri CD
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Healthcare epidemiology: quorum sensing: bacteria talk sense.
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Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
bph02040  Flagellar assembly
KO pathway
ko02024   
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