KEGG   PATHWAY: dfn02024
Entry
dfn02024                    Pathway                                
Name
Quorum sensing - Dickeya fangzhongdai DSM 101947
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
dfn02024  Quorum sensing
dfn02024

Other DBs
GO: 0009372
Organism
Dickeya fangzhongdai DSM 101947 [GN:dfn]
Gene
CVE23_17035  S-ribosylhomocysteine lyase [KO:K07173] [EC:4.4.1.21]
CVE23_19465  RNA chaperone Hfq [KO:K03666]
CVE23_11030  anthranilate synthase component 1 [KO:K01657] [EC:4.1.3.27]
CVE23_11025  anthranilate synthase component II [KO:K01658] [EC:4.1.3.27]
CVE23_09805  alpha/beta hydrolase [KO:K18100] [EC:2.4.1.-]
CVE23_14440  glycosyltransferase [KO:K18101] [EC:2.4.1.-]
CVE23_16990  3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
CVE23_06985  3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
CVE23_13555  3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
CVE23_22230  two-component system sensor histidine kinase QseC [KO:K07645] [EC:2.7.13.3]
CVE23_22225  DNA-binding response regulator [KO:K07666]
CVE23_16485  sensor histidine kinase [KO:K07711] [EC:2.7.13.3]
CVE23_16475  two-component system response regulator GlrR [KO:K07715]
CVE23_14315  flagellar transcriptional regulator FlhD [KO:K02403]
CVE23_14310  flagellar transcriptional regulator FlhC [KO:K02402]
CVE23_06775  two-component system response regulator KdpE [KO:K07667]
CVE23_07350  LuxR family transcriptional regulator [KO:K07782]
CVE23_12410  spermidine/putrescine ABC transporter substrate-binding protein [KO:K02055]
CVE23_11405  ABC transporter substrate-binding protein [KO:K02055]
CVE23_18200  ABC transporter substrate-binding protein [KO:K02055]
CVE23_12400  ABC transporter permease [KO:K02053]
CVE23_11410  ABC transporter permease [KO:K02053]
CVE23_18185  ABC transporter permease [KO:K02053]
CVE23_12405  ABC transporter permease [KO:K02054]
CVE23_11415  spermidine/putrescine ABC transporter permease [KO:K02054]
CVE23_18190  ABC transporter permease [KO:K02054]
CVE23_12430  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
CVE23_18180  ABC transporter ATP-binding protein [KO:K02052]
CVE23_11420  ABC transporter ATP-binding protein [KO:K02052]
CVE23_19065  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
CVE23_21555  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
CVE23_19060  branched-chain amino acid ABC transporter permease [KO:K01997]
CVE23_21550  high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997]
CVE23_21545  livM; high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998]
CVE23_19055  branched-chain amino acid ABC transporter permease [KO:K01998]
CVE23_19050  livG; ABC transporter ATP-binding protein [KO:K01995]
CVE23_21540  livG; ABC transporter ATP-binding protein [KO:K01995]
CVE23_21535  high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996]
CVE23_19045  ABC transporter ATP-binding protein [KO:K01996]
CVE23_00610  acyl-homoserine-lactone synthase [KO:K22956] [EC:2.3.1.184]
CVE23_00605  LuxR family transcriptional regulator [KO:K19734]
CVE23_20470  pectate lyase [KO:K01728] [EC:4.2.2.2]
CVE23_20475  pectate lyase [KO:K01728] [EC:4.2.2.2]
CVE23_16445  pectate lyase [KO:K01728] [EC:4.2.2.2]
CVE23_16450  pectate lyase [KO:K01728] [EC:4.2.2.2]
CVE23_16455  pectate lyase [KO:K01728] [EC:4.2.2.2]
CVE23_04890  thrombospondin [KO:K20276]
CVE23_11805  long-chain-fatty-acid--CoA ligase FadD [KO:K01897] [EC:6.2.1.3]
CVE23_18925  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
CVE23_20415  cAMP-activated global transcriptional regulator CRP [KO:K10914]
CVE23_03295  transcriptional regulator Zur [KO:K09823]
CVE23_13205  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
CVE23_05870  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
CVE23_08565  efflux transporter periplasmic adaptor subunit [KO:K18306]
CVE23_08570  multidrug efflux protein [KO:K18307]
CVE23_14545  transporter [KO:K18139]
CVE23_12995  oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580]
CVE23_10925  oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580]
CVE23_13210  oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580]
CVE23_10930  oligopeptide ABC transporter permease OppB [KO:K15581]
CVE23_10935  oligopeptide ABC transporter permease OppC [KO:K15582]
CVE23_10940  oppD; oligopeptide ABC transporter ATP-binding protein OppD [KO:K15583]
CVE23_10945  oligopeptide ABC transporter ATP-binding protein OppF [KO:K10823]
CVE23_07375  diguanylate cyclase [KO:K02035]
CVE23_01995  ABC transporter substrate-binding protein [KO:K02035]
CVE23_10765  ABC transporter substrate-binding protein [KO:K02035]
CVE23_04025  ABC transporter substrate-binding protein [KO:K02035]
CVE23_12840  ABC transporter substrate-binding protein [KO:K02035]
CVE23_08710  ABC transporter substrate-binding protein [KO:K02035]
CVE23_02330  ABC transporter substrate-binding protein [KO:K02035]
CVE23_02480  ABC transporter substrate-binding protein [KO:K02035]
CVE23_00220  TIGR04028 family ABC transporter substrate-binding protein [KO:K02035]
CVE23_09120  peptide ABC transporter [KO:K02035]
CVE23_09425  ABC transporter substrate-binding protein [KO:K02035]
CVE23_00685  ABC transporter substrate-binding protein [KO:K02035]
CVE23_02335  ABC transporter permease [KO:K02033]
CVE23_07355  ABC transporter permease [KO:K02033]
CVE23_02000  ABC transporter permease [KO:K02033]
CVE23_10760  ABC transporter permease [KO:K02033 K02034]
CVE23_04030  ABC transporter permease [KO:K02033]
CVE23_12860  ABC transporter permease [KO:K02033]
CVE23_08735  ABC transporter permease [KO:K02033]
CVE23_02475  ABC transporter permease [KO:K02033]
CVE23_00215  ABC transporter permease [KO:K02033]
CVE23_09135  ABC transporter permease [KO:K02033]
CVE23_09430  ABC transporter permease [KO:K02033]
CVE23_00690  ABC transporter permease [KO:K02033]
CVE23_07360  nickel ABC transporter permease [KO:K02034]
CVE23_02005  ABC transporter permease [KO:K02034]
CVE23_04035  ABC transporter permease [KO:K02034]
CVE23_12855  peptide ABC transporter permease [KO:K02034]
CVE23_08740  ABC transporter permease [KO:K02034]
CVE23_02340  peptide ABC transporter permease [KO:K02034]
CVE23_02470  peptide ABC transporter permease [KO:K02034]
CVE23_00210  ABC transporter permease [KO:K02034]
CVE23_09140  ABC transporter permease [KO:K02034]
CVE23_09435  peptide ABC transporter permease [KO:K02034]
CVE23_00695  ABC transporter permease [KO:K02034]
CVE23_07365  methionine ABC transporter ATP-binding protein [KO:K02031]
CVE23_02010  ABC transporter [KO:K02031 K02032]
CVE23_10775  dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein [KO:K02031]
CVE23_04040  peptide ABC transporter ATP-binding protein [KO:K02031]
CVE23_12850  ABC transporter ATP-binding protein [KO:K02031]
CVE23_08745  glutathione ABC transporter ATP-binding protein GsiA [KO:K02031 K02032]
CVE23_02345  ABC transporter ATP-binding protein [KO:K02031]
CVE23_02465  ABC transporter ATP-binding protein [KO:K02031 K02032]
CVE23_00205  ABC transporter ATP-binding protein [KO:K02031 K02032]
CVE23_09125  ABC transporter ATP-binding protein [KO:K02031]
CVE23_09440  peptide ABC transporter ATP-binding protein [KO:K02031]
CVE23_00700  peptide ABC transporter ATP-binding protein [KO:K02031]
CVE23_04045  ABC transporter ATP-binding protein [KO:K02032]
CVE23_10770  ABC transporter ATP-binding protein [KO:K02032]
CVE23_09445  peptide ABC transporter substrate-binding protein [KO:K02032]
CVE23_02350  ABC transporter ATP-binding protein [KO:K02032]
CVE23_00705  ABC transporter ATP-binding protein [KO:K02032]
CVE23_22520  membrane protein insertase YidC [KO:K03217]
CVE23_01150  preprotein translocase subunit SecE [KO:K03073]
CVE23_03580  preprotein translocase subunit SecG [KO:K03075]
CVE23_20160  preprotein translocase subunit SecY [KO:K03076]
CVE23_05835  preprotein translocase subunit YajC [KO:K03210]
CVE23_18815  preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
CVE23_21580  signal recognition particle-docking protein FtsY [KO:K03110]
CVE23_00905  protein-export chaperone SecB [KO:K03071]
CVE23_17025  signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
CVE23_03870  phosphoesterase [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
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Bacterial quorum sensing: its role in virulence and possibilities for its control.
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Microbiol Mol Biol Rev 77:73-111 (2013)
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Clin Infect Dis 47:1070-6 (2008)
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Related
pathway
dfn02040  Flagellar assembly
KO pathway
ko02024   
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