KEGG   PATHWAY: fab04070
Entry
fab04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Ficedula albicollis (collared flycatcher)
Class
Environmental Information Processing; Signal transduction
Pathway map
fab04070  Phosphatidylinositol signaling system
fab04070

Organism
Ficedula albicollis (collared flycatcher) [GN:fab]
Gene
101813375  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
101812598  PI4KB; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
101811224  hyphally-regulated protein-like [KO:K19801] [EC:2.7.1.67]
101807823  PI4K2B; phosphatidylinositol 4-kinase type 2 beta [KO:K13711] [EC:2.7.1.67]
101821927  PI4K2A; phosphatidylinositol 4-kinase type 2 alpha [KO:K13711] [EC:2.7.1.67]
101811241  SACM1L; SAC1 suppressor of actin mutations 1-like (yeast) [KO:K21797] [EC:3.1.3.-]
101814095  INPP5F; inositol polyphosphate-5-phosphatase F [KO:K21798] [EC:3.1.3.-]
101807917  PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta [KO:K00889] [EC:2.7.1.68]
101808443  PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [KO:K00889] [EC:2.7.1.68]
101809360  INPP5B; inositol polyphosphate-5-phosphatase B [KO:K01099] [EC:3.1.3.36]
101813228  OCRL; OCRL, inositol polyphosphate-5-phosphatase [KO:K01099] [EC:3.1.3.36]
101814688  INPP5E; inositol polyphosphate-5-phosphatase E [KO:K20278] [EC:3.1.3.36]
101806093  SYNJ1; synaptojanin 1 [KO:K20279] [EC:3.1.3.36]
101807630  SYNJ2; synaptojanin 2 [KO:K20279] [EC:3.1.3.36]
101807806  synaptojanin-1-like [KO:K20279] [EC:3.1.3.36]
101811931  PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
101821801  PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [KO:K00922] [EC:2.7.1.153]
101814811  PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
101820843  PIK3R1; phosphoinositide-3-kinase regulatory subunit 1 [KO:K02649]
101811808  PIK3R2; phosphoinositide-3-kinase regulatory subunit 2 [KO:K02649]
101812251  PIK3R3; phosphoinositide-3-kinase regulatory subunit 3 [KO:K02649]
101815785  PTEN; phosphatase and tensin homolog [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
101809542  INPP5D; inositol polyphosphate-5-phosphatase D [KO:K03084] [EC:3.1.3.86]
101807549  INPPL1; inositol polyphosphate phosphatase like 1 [KO:K15909] [EC:3.1.3.86]
101820739  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2-like [KO:K15909] [EC:3.1.3.86]
101806527  INPP4A; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
101812696  INPP4B; inositol polyphosphate-4-phosphatase type II B [KO:K01109] [EC:3.1.3.66]
101821332  PIKFYVE; phosphoinositide kinase, FYVE-type zinc finger containing [KO:K00921] [EC:2.7.1.150]
101819090  MTM1; myotubularin 1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
101818420  MTMR2; myotubularin related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101819675  MTMR1; myotubularin related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101815162  MTMR4; myotubularin related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101816909  MTMR3; myotubularin related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101811909  MTMR8; myotubularin related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101812336  MTMR6; myotubularin related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101821855  MTMR7; myotubularin related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101807592  MTMR14; myotubularin related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
101806091  PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase type 2 beta [KO:K00920] [EC:2.7.1.149]
107604462  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like [KO:K00920] [EC:2.7.1.149]
101812492  PIP4K2A; phosphatidylinositol-5-phosphate 4-kinase type 2 alpha [KO:K00920] [EC:2.7.1.149]
101810791  TMEM55A; transmembrane protein 55A [KO:K13084] [EC:3.1.3.78]
101819120  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
101810900  PIK3C2B; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [KO:K00923] [EC:2.7.1.154]
101811315  PIK3C2G; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [KO:K00923] [EC:2.7.1.154]
101813229  PIK3C2A; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [KO:K00923] [EC:2.7.1.154]
101816169  PLCB1; phospholipase C beta 1 [KO:K05858] [EC:3.1.4.11]
101812094  PLCB4; phospholipase C beta 4 [KO:K05858] [EC:3.1.4.11]
101806047  PLCB2; phospholipase C beta 2 [KO:K05858] [EC:3.1.4.11]
101809831  PLCD3; phospholipase C delta 3 [KO:K05857] [EC:3.1.4.11]
101816161  PLCD1; phospholipase C delta 1 [KO:K05857] [EC:3.1.4.11]
101817537  PLCD4; phospholipase C delta 4 [KO:K05857] [EC:3.1.4.11]
101810240  PLCE1; phospholipase C epsilon 1 [KO:K05860] [EC:3.1.4.11]
101820005  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like [KO:K01116] [EC:3.1.4.11]
101806517  PLCG1; phospholipase C gamma 1 [KO:K01116] [EC:3.1.4.11]
101811465  PLCG2; phospholipase C gamma 2 [KO:K05859] [EC:3.1.4.11]
101810163  PLCZ1; phospholipase C zeta 1 [KO:K05861] [EC:3.1.4.11]
101808343  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
101821716  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
101805979  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
101814745  INPP5A; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
101819235  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
101814368  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
101809490  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
101814369  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
101811852  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
101820580  PPIP5K2; diphosphoinositol pentakisphosphate kinase 2 [KO:K13024] [EC:2.7.4.24]
101808161  PPIP5K1; diphosphoinositol pentakisphosphate kinase 1 [KO:K13024] [EC:2.7.4.24]
101810227  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
101807435  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
101819036  IMPAD1; inositol monophosphatase domain containing 1 [KO:K15759] [EC:3.1.3.7]
101807694  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
101820513  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
101814363  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
101809637  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
101819311  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
101821710  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
101811751  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
101806481  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
101813695  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
101820305  CDS2; CDP-diacylglycerol synthase 2 [KO:K00981] [EC:2.7.7.41]
101810662  CDS1; CDP-diacylglycerol synthase 1 [KO:K00981] [EC:2.7.7.41]
101816592  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
101811180  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
101809694  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
101810891  PRKCA; protein kinase C alpha [KO:K02677] [EC:2.7.11.13]
101820883  PRKCB; protein kinase C beta [KO:K19662] [EC:2.7.11.13]
101817508  calmodulin, striated muscle [KO:K02183]
101813679  CALM2; calmodulin 2 [KO:K02183]
101808084  CALM1; calmodulin 1 [KO:K02183]
101818195  CALML4; calmodulin like 4 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
fab04020  Calcium signaling pathway
fab04144  Endocytosis
fab04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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