KEGG   PATHWAY: han00270
Entry
han00270                    Pathway                                
Name
Cysteine and methionine metabolism - Helianthus annuus (common sunflower)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
han00270  Cysteine and methionine metabolism
han00270

Module
han_M00021  Cysteine biosynthesis, serine => cysteine [PATH:han00270]
han_M00034  Methionine salvage pathway [PATH:han00270]
han_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:han00270]
Other DBs
GO: 0006534 0006555
Organism
Helianthus annuus (common sunflower) [GN:han]
Gene
110909079  serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
110880212  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
110889392  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
110893733  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
110929779  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
110890001  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
110885058  cysteine synthase [KO:K01738] [EC:2.5.1.47]
110885059  cysteine synthase [KO:K01738] [EC:2.5.1.47]
110879587  cysteine synthase [KO:K01738] [EC:2.5.1.47]
110927332  cysteine synthase isoform X1 [KO:K01738] [EC:2.5.1.47]
110918288  cysteine synthase [KO:K01738] [EC:2.5.1.47]
110942118  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
110864795  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
110937631  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
110865347  cystathionine beta-lyase, chloroplastic [KO:K01760] [EC:4.4.1.13]
110867261  cystathionine beta-lyase, chloroplastic isoform X1 [KO:K01760] [EC:4.4.1.13]
110884097  homocysteine S-methyltransferase 2 [KO:K00547] [EC:2.1.1.10]
110872038  homocysteine S-methyltransferase 2 [KO:K00547] [EC:2.1.1.10]
110915104  homocysteine S-methyltransferase 1 [KO:K00547] [EC:2.1.1.10]
110868496  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
110898235  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like isoform X1 [KO:K00549] [EC:2.1.1.14]
110898236  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like isoform X1 [KO:K00549] [EC:2.1.1.14]
110898392  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
110868285  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
110881749  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
110924399  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
110891286  S-adenosylmethionine synthase 3-like isoform X1 [KO:K00789] [EC:2.5.1.6]
110904492  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
110941174  S-adenosylmethionine synthase 5 [KO:K00789] [EC:2.5.1.6]
110868114  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
110903851  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
110872140  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
110873044  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
110894551  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
110911041  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
110926184  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
110895040  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
110878171  spermine synthase [KO:K00797] [EC:2.5.1.16]
110897763  spermine synthase [KO:K00797] [EC:2.5.1.16]
110885610  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
110890233  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
110877899  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
110913169  probable nicotianamine synthase 4 [KO:K05953] [EC:2.5.1.43]
110932790  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
110885112  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [KO:K01244] [EC:3.2.2.16]
110885281  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
110868075  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
110879640  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 isoform X1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
110894473  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 isoform X1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
110915626  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
118487494  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 3 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
110917231  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
110885705  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
110897482  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
110925732  tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
110922226  nicotianamine aminotransferase 1 [KO:K00815] [EC:2.6.1.5]
110916572  aromatic aminotransferase ISS1 isoform X2 [KO:K00837] [EC:2.6.1.-]
110940487  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
110863697  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
110923540  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
110926138  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
110926215  DNA (cytosine-5)-methyltransferase CMT2 [KO:K00558] [EC:2.1.1.37]
110911600  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
110920934  DNA (cytosine-5)-methyltransferase CMT3 isoform X1 [KO:K00558] [EC:2.1.1.37]
110891067  DNA (cytosine-5)-methyltransferase 1B [KO:K00558] [EC:2.1.1.37]
110937518  DNA (cytosine-5)-methyltransferase 1B [KO:K00558] [EC:2.1.1.37]
110890457  uncharacterized protein LOC110890457 [KO:K17398] [EC:2.1.1.37]
110912123  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
110877325  adenosylhomocysteinase 1 isoform X1 [KO:K01251] [EC:3.13.2.1]
110864420  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
110922539  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
110922546  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
110897828  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
118489062  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
110865480  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
110883606  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
110922519  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
110895485  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
110911122  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
110911123  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
110909510  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
110936703  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
110936878  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
110910826  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
110885987  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
110885989  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
110928496  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
110910493  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
110888109  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
110941265  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
110941268  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
110939598  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
110868570  aspartokinase 2, chloroplastic [KO:K00928] [EC:2.7.2.4]
110926416  aspartokinase 2, chloroplastic isoform X1 [KO:K00928] [EC:2.7.2.4]
110879567  bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
110924030  bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
110894530  aspartate-semialdehyde dehydrogenase [KO:K00133] [EC:1.2.1.11]
110878986  cystathionine gamma-synthase 1, chloroplastic [KO:K01739] [EC:2.5.1.48]
110889434  cystathionine gamma-synthase 1, chloroplastic [KO:K01739] [EC:2.5.1.48]
110867982  branched-chain amino acid aminotransferase 2, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
110873035  branched-chain-amino-acid aminotransferase 2, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
110873037  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
110897576  branched-chain-amino-acid aminotransferase 2, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
110897603  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
110884572  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
110918713  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
110910958  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
110903697  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
110866076  glutamate--cysteine ligase, chloroplastic isoform X1 [KO:K01919] [EC:6.3.2.2]
110926229  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
110885127  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
110903719  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
110873794  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
110893793  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
110921076  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
110882526  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
110898604  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
110923256  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
110890161  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial [KO:K01011] [EC:2.8.1.1 2.8.1.2]
110864287  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
110922114  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
110898022  L-lactate dehydrogenase A [KO:K00016] [EC:1.1.1.27]
110921871  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
118489105  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
110895064  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
110915076  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
110884362  L-cysteine desulfhydrase [KO:K22207] [EC:4.4.1.28]
110877155  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
110930874  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
110900006  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
110916505  malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
110940320  malate dehydrogenase, cytoplasmic isoform X2 [KO:K00025] [EC:1.1.1.37]
110895209  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
110895498  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
110879703  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
110885871  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
110909316  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
110918197  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
110885627  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
110915392  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
110935433  D-3-phosphoglycerate dehydrogenase 3, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
110872406  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
110876136  phosphoserine aminotransferase 2, chloroplastic [KO:K00831] [EC:2.6.1.52]
110897548  phosphoserine aminotransferase 2, chloroplastic [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
han00010  Glycolysis / Gluconeogenesis
han00250  Alanine, aspartate and glutamate metabolism
han00260  Glycine, serine and threonine metabolism
han00290  Valine, leucine and isoleucine biosynthesis
han00430  Taurine and hypotaurine metabolism
han00480  Glutathione metabolism
han00620  Pyruvate metabolism
han00640  Propanoate metabolism
han00770  Pantothenate and CoA biosynthesis
han00900  Terpenoid backbone biosynthesis
han00920  Sulfur metabolism
KO pathway
ko00270   
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