Entry Name ABC transporters - Leptothrix cholodnii
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Leptothrix cholodnii [GN:
lch ]
Gene Lcho_3804 sulfate ABC transporter, periplasmic sulfate-binding protein [KO:K23163 ]
Lcho_1356 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
Lcho_2103 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Lcho_4318 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Lcho_1734 binding-protein-dependent transport systems inner membrane component [KO:K11075 ]
Lcho_0890 binding-protein-dependent transport systems inner membrane component [KO:K10228 ]
Lcho_0137 binding-protein-dependent transport systems inner membrane component [KO:K10228 ]
Lcho_0136 binding-protein-dependent transport systems inner membrane component [KO:K10229 ]
Lcho_0891 binding-protein-dependent transport systems inner membrane component [KO:K10229 ]
Lcho_3328 binding-protein-dependent transport systems inner membrane component [KO:K10237 ]
Lcho_3327 binding-protein-dependent transport systems inner membrane component [KO:K10238 ]
Lcho_3200 sugar ABC transporter, periplasmic sugar-binding protein [KO:K10546 ]
Lcho_4322 binding-protein-dependent transport systems inner membrane component [KO:K17316 ]
Lcho_1694 binding-protein-dependent transport systems inner membrane component [KO:K17316 ]
Lcho_4323 binding-protein-dependent transport systems inner membrane component [KO:K17317 ]
Lcho_1693 binding-protein-dependent transport systems inner membrane component [KO:K17317 ]
Lcho_3294 periplasmic binding protein/LacI transcriptional regulator [KO:K10439 ]
Lcho_0841 ABC sugar transporter, periplasmic solute-binding protein [KO:K10543 ]
Lcho_2221 periplasmic binding protein/LacI transcriptional regulator [KO:K10552 ]
Lcho_2212 rhamnose ABC transporter, periplasmic rhamnose-binding protein [KO:K10559 ]
Lcho_3313 periplasmic binding protein/LacI transcriptional regulator [KO:K17213 ]
Lcho_2814 phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
Lcho_2813 phosphate ABC transporter, inner membrane subunit PstC [KO:K02037 ]
Lcho_1655 phosphate ABC transporter, inner membrane subunit PstC [KO:K02037 ]
Lcho_2812 phosphate ABC transporter, inner membrane subunit PstA [KO:K02038 ]
Lcho_1656 phosphate ABC transporter, inner membrane subunit PstA [KO:K02038 ]
Lcho_1723 phosphonate ABC transporter, periplasmic phosphonate-binding protein [KO:K02044 ]
Lcho_1721 binding-protein-dependent transport systems inner membrane component [KO:K02042 ]
Lcho_2686 polar amino acid ABC transporter, inner membrane subunit [KO:K10002 ]
Lcho_4022 polar amino acid ABC transporter, inner membrane subunit [KO:K10002 ]
Lcho_2687 polar amino acid ABC transporter, inner membrane subunit [KO:K10003 ]
Lcho_4023 polar amino acid ABC transporter, inner membrane subunit [KO:K10003 ]
Lcho_2137 polar amino acid ABC transporter, inner membrane subunit [KO:K09970 ]
Lcho_2138 polar amino acid ABC transporter, inner membrane subunit [KO:K09971 ]
Lcho_1274 binding-protein-dependent transport systems inner membrane component [KO:K13894 ]
Lcho_1273 binding-protein-dependent transport systems inner membrane component [KO:K13895 ]
Lcho_2398 lipoprotein releasing system, transmembrane protein, LolC/E family [KO:K09808 ]
Lcho_2397 lipoprotein releasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
