KEGG   PATHWAY: mln00230
Entry
mln00230                    Pathway                                
Name
Purine metabolism - Mesorhizobium loti NZP2037
Class
Metabolism; Nucleotide metabolism
Pathway map
mln00230  Purine metabolism
mln00230

Module
mln_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mln00230]
mln_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mln00230]
mln_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mln00230]
mln_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mln00230]
mln_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mln00230]
mln_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mln00230]
Other DBs
GO: 0006163 0042278
Organism
Mesorhizobium loti NZP2037 [GN:mln]
Gene
A9174_33615  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
A9174_34490  phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
A9174_28075  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
A9174_11510  phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
A9174_27100  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
A9174_28615  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
A9174_26610  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
A9174_24565  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
A9174_24525  phosphoribosylformylglycinamidine synthase [KO:K23264] [EC:6.3.5.3]
A9174_24535  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
A9174_26605  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
A9174_06740  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
A9174_06745  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
A9174_11800  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
A9174_24520  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
A9174_24490  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
A9174_05765  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
A9174_11440  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
A9174_09780  multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
A9174_07495  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
A9174_20835  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
A9174_09255  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
A9174_21900  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
A9174_11525  polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
A9174_16725  rihB; ribonucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
A9174_07960  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
A9174_25590  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
A9174_26800  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
A9174_03895  non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
A9174_24255  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
A9174_01810  xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
A9174_01805  xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
A9174_16980  oxidoreductase [KO:K11177] [EC:1.17.1.4]
A9174_16985  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
A9174_16990  (2Fe-2S)-binding protein [KO:K13483]
A9174_05360  GMP synthase [KO:K01951] [EC:6.3.5.2]
A9174_14515  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
A9174_01775  guanine deaminase [KO:K01487] [EC:3.5.4.3]
A9174_26995  guanylate kinase [KO:K00942] [EC:2.7.4.8]
A9174_24270  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
A9174_20785  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
A9174_27300  hydrolase [KO:K06952] [EC:3.1.3.89]
A9174_27405  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
A9174_26430  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
A9174_25605  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
A9174_12550  hypothetical protein [KO:K07816] [EC:2.7.6.5]
A9174_04020  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
A9174_06495  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
A9174_09235  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
A9174_27550  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
A9174_24170  adenine deaminase [KO:K01486] [EC:3.5.4.2]
A9174_23340  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
A9174_06210  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
A9174_23530  adenylate kinase [KO:K00939] [EC:2.7.4.3]
A9174_23185  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
A9174_08040  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
A9174_07435  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
A9174_28140  adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
A9174_28145  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
A9174_34040  oxidoreductase [KO:K22879] [EC:1.14.13.113]
A9174_01815  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
A9174_25240  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
A9174_01820  OHCU decarboxylase [KO:K16842] [EC:3.5.2.5]
A9174_01825  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
A9174_01830  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
A9174_02705  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
A9174_02690  urease subunit beta [KO:K01429] [EC:3.5.1.5]
A9174_02675  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
A9174_15015  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mln00030  Pentose phosphate pathway
mln00220  Arginine biosynthesis
mln00250  Alanine, aspartate and glutamate metabolism
mln00260  Glycine, serine and threonine metabolism
mln00340  Histidine metabolism
mln00630  Glyoxylate and dicarboxylate metabolism
mln00730  Thiamine metabolism
mln00740  Riboflavin metabolism
mln00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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