KEGG   PATHWAY: mmat00230
Entry
mmat00230                   Pathway                                
Name
Purine metabolism - Mycolicibacterium mageritense
Class
Metabolism; Nucleotide metabolism
Pathway map
mmat00230  Purine metabolism
mmat00230

Module
mmat_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mmat00230]
mmat_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mmat00230]
mmat_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mmat00230]
mmat_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mmat00230]
mmat_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mmat00230]
mmat_M00546  Purine degradation, xanthine => urea [PATH:mmat00230]
mmat_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mmat00230]
mmat_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mmat00230]
Other DBs
GO: 0006163 0042278
Organism
Mycolicibacterium mageritense [GN:mmat]
Gene
MMAGJ_50740  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
MMAGJ_07320  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MMAGJ_12290  hypothetical protein [KO:K00948] [EC:2.7.6.1]
MMAGJ_12810  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MMAGJ_13190  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MMAGJ_08800  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MMAGJ_35770  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
MMAGJ_12890  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
MMAGJ_13000  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
MMAGJ_12990  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MMAGJ_12800  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MMAGJ_47470  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MMAGJ_47480  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MMAGJ_13080  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MMAGJ_13140  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MMAGJ_08790  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MMAGJ_59460  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MMAGJ_54390  haloacid dehalogenase [KO:K02566] [EC:3.1.3.5]
MMAGJ_46300  punA; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MMAGJ_71910  laccase domain protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MMAGJ_44930  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
MMAGJ_32960  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MMAGJ_44690  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MMAGJ_44700  putative oxidoreductase [KO:K00088] [EC:1.1.1.205]
MMAGJ_76680  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MMAGJ_01670  rdgB; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
MMAGJ_76340  dehydrogenase [KO:K00087] [EC:1.17.1.4]
MMAGJ_14180  xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
MMAGJ_51760  aldehyde oxidase [KO:K11177] [EC:1.17.1.4]
MMAGJ_14170  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
MMAGJ_51780  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
MMAGJ_14160  oxidoreductase [KO:K13483]
MMAGJ_51770  oxidoreductase [KO:K13483]
MMAGJ_44810  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
MMAGJ_66660  inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
MMAGJ_09840  guanine deaminase [KO:K01487] [EC:3.5.4.3]
MMAGJ_60610  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MMAGJ_52200  nrdE2; ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
MMAGJ_18630  nrdB; R2-like ligand binding oxidase [KO:K00526] [EC:1.17.4.1]
MMAGJ_52780  nrdF2; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MMAGJ_75150  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
MMAGJ_59470  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MMAGJ_07120  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MMAGJ_38510  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MMAGJ_47030  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MMAGJ_74970  cyclase [KO:K01768] [EC:4.6.1.1]
MMAGJ_01120  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MMAGJ_03090  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MMAGJ_20230  cyclase [KO:K01768] [EC:4.6.1.1]
MMAGJ_24980  cyclase [KO:K01768] [EC:4.6.1.1]
MMAGJ_32470  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MMAGJ_62760  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
MMAGJ_63310  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
MMAGJ_13250  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MMAGJ_72380  adenosine kinase [KO:K00856] [EC:2.7.1.20]
MMAGJ_02500  hypothetical protein [KO:K00856] [EC:2.7.1.20]
MMAGJ_46130  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MMAGJ_43570  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
MMAGJ_07250  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MMAGJ_59180  diadenosine polyphosphate hydrolase [KO:K19710] [EC:2.7.7.53]
MMAGJ_02600  cysNC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MMAGJ_14770  adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
MMAGJ_02610  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
MMAGJ_14760  sulfate adenylyltransferase [KO:K00957] [EC:2.7.7.4]
MMAGJ_63580  uricase [KO:K00365] [EC:1.7.3.3]
MMAGJ_63570  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MMAGJ_32910  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
MMAGJ_63560  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
MMAGJ_63470  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
MMAGJ_63550  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
MMAGJ_63540  alc; putative allantoicase [KO:K01477] [EC:3.5.3.4]
MMAGJ_13480  hypothetical protein [KO:K14977] [EC:3.5.3.26]
MMAGJ_11850  ureC1; urease subunit alpha 1 [KO:K01428] [EC:3.5.1.5]
MMAGJ_66580  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
MMAGJ_66590  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
MMAGJ_66600  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
MMAGJ_11840  ureAB; urease subunit gamma/beta [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mmat00030  Pentose phosphate pathway
mmat00220  Arginine biosynthesis
mmat00250  Alanine, aspartate and glutamate metabolism
mmat00260  Glycine, serine and threonine metabolism
mmat00340  Histidine metabolism
mmat00630  Glyoxylate and dicarboxylate metabolism
mmat00730  Thiamine metabolism
mmat00740  Riboflavin metabolism
mmat00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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