KEGG   PATHWAY: msam00350
Entry
msam00350                   Pathway                                
Name
Tyrosine metabolism - Micropterus salmoides (largemouth bass)
Class
Metabolism; Amino acid metabolism
Pathway map
msam00350  Tyrosine metabolism
msam00350

Module
msam_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:msam00350]
msam_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:msam00350]
msam_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:msam00350]
Other DBs
GO: 0006570
Organism
Micropterus salmoides (largemouth bass) [GN:msam]
Gene
119898188  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
119917270  got1; LOW QUALITY PROTEIN: aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
119891996  got1l1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
119890997  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
119893226  tat; tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
119882627  il4i1; L-amino-acid oxidase isoform X1 [KO:K03334] [EC:1.4.3.2]
119918947  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
119918948  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
119912615  L-amino-acid oxidase-like isoform X1 [KO:K03334] [EC:1.4.3.2]
119912745  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
119896366  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
119892439  hpdb; 4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
119895910  hpda; 4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
119911736  LOW QUALITY PROTEIN: homogentisate 1,2-dioxygenase-like [KO:K00451] [EC:1.13.11.5]
119908883  hgd; homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
119909982  gstz1; maleylacetoacetate isomerase isoform X1 [KO:K01800] [EC:5.2.1.2]
119882899  fah; fumarylacetoacetase isoform X1 [KO:K01555] [EC:3.7.1.2]
119883400  tyr; tyrosinase [KO:K00505] [EC:1.14.18.1]
119895337  tyrosinase-like [KO:K00505] [EC:1.14.18.1]
119917964  th2; tyrosine hydroxylase 2 [KO:K00501] [EC:1.14.16.2]
119894432  th; tyrosine 3-monooxygenase [KO:K00501] [EC:1.14.16.2]
119904151  dct; L-dopachrome tautomerase [KO:K01827] [EC:5.3.3.12]
119899129  tyrp1b; tyrosinase-related protein 1b [KO:K00506] [EC:1.14.18.-]
119912504  5,6-dihydroxyindole-2-carboxylic acid oxidase-like [KO:K00506] [EC:1.14.18.-]
119897905  ddc; aromatic-L-amino-acid decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
119882201  dopamine beta-hydroxylase-like [KO:K00503] [EC:1.14.17.1]
119914708  dbh; LOW QUALITY PROTEIN: dopamine beta-hydroxylase [KO:K00503] [EC:1.14.17.1]
119916634  phenylethanolamine N-methyltransferase [KO:K00553] [EC:2.1.1.28]
119883576  tomt; transmembrane O-methyltransferase homolog [KO:K00545] [EC:2.1.1.6]
119905549  comta; catechol O-methyltransferase A [KO:K00545] [EC:2.1.1.6]
119886699  catechol O-methyltransferase B-like [KO:K00545] [EC:2.1.1.6]
119886780  LOW QUALITY PROTEIN: catechol O-methyltransferase B-like [KO:K00545] [EC:2.1.1.6]
119888919  catechol O-methyltransferase-like [KO:K00545] [EC:2.1.1.6]
119904600  mao; amine oxidase [flavin-containing] [KO:K00274] [EC:1.4.3.4]
119915066  si:ch211-127i16.2; probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
119918397  aoc2; retina-specific copper amine oxidase [KO:K00276] [EC:1.4.3.21]
119892309  aldh3b2; aldehyde dehydrogenase family 3 member B1 [KO:K00129] [EC:1.2.1.5]
119896428  aldh3b1; aldehyde dehydrogenase family 3 member B1 [KO:K00129] [EC:1.2.1.5]
119888261  alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
119888263  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
119910194  alcohol dehydrogenase 1-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
119910195  alcohol dehydrogenase 1-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
119910199  alcohol dehydrogenase 1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
119910842  tpo; thyroid peroxidase [KO:K00431] [EC:1.11.1.8]
119893789  epx; eosinophil peroxidase [KO:K00431] [EC:1.11.1.8]
119905158  aox6; aldehyde oxidase 6 [KO:K00157] [EC:1.2.3.1]
119889065  fahd1; acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
119896359  LOW QUALITY PROTEIN: acylpyruvase FAHD1, mitochondrial-like [KO:K01557] [EC:3.7.1.5]
119887751  macrophage migration inhibitory factor-like [KO:K07253] [EC:5.3.2.1]
119888943  macrophage migration inhibitory factor-like [KO:K07253] [EC:5.3.2.1]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
msam00020  Citrate cycle (TCA cycle)
msam00360  Phenylalanine metabolism
msam00400  Phenylalanine, tyrosine and tryptophan biosynthesis
msam00620  Pyruvate metabolism
msam00650  Butanoate metabolism
KO pathway
ko00350   
LinkDB

DBGET integrated database retrieval system