KEGG   PATHWAY: phyp00564
Entry
phyp00564                   Pathway                                
Name
Glycerophospholipid metabolism - Pangasianodon hypophthalmus (striped catfish)
Class
Metabolism; Lipid metabolism
Pathway map
phyp00564  Glycerophospholipid metabolism
phyp00564

Module
phyp_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:phyp00564]
phyp_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:phyp00564]
phyp_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:phyp00564]
Other DBs
GO: 0006650
Organism
Pangasianodon hypophthalmus (striped catfish) [GN:phyp]
Gene
113538032  gpd1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
113535164  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
113526606  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
113525376  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
113538335  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
113527513  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
113546033  glycerol-3-phosphate acyltransferase 2, mitochondrial-like [KO:K00629] [EC:2.3.1.15]
113528164  glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
113533124  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
113543179  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
113544062  glycerol-3-phosphate acyltransferase 4-like [KO:K13506] [EC:2.3.1.15]
113535814  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
113537458  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
113544299  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
113542003  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
113541993  lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
113538784  membrane-bound O-acyltransferase domain-containing protein 2-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113532392  membrane-bound O-acyltransferase domain-containing protein 2-like isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113533691  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113528766  dihydroxyacetone phosphate acyltransferase-like isoform X1 [KO:K00649] [EC:2.3.1.42]
113529083  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
113527145  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
113546273  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
113533363  plpp2; phospholipid phosphatase 2 isoform X1 [KO:K01080] [EC:3.1.3.4]
113535909  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
113547295  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
113543993  plpp1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
113545159  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
113540483  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
113528692  phosphatidate phosphatase LPIN1-like [KO:K15728] [EC:3.1.3.4]
113531373  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
113539963  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
113533926  phosphatidate phosphatase LPIN1-like isoform X1 [KO:K15728] [EC:3.1.3.4]
113543935  plpp5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
113541883  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
113546735  dgkz; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
113530152  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
113524181  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
113539908  diacylglycerol kinase eta-like [KO:K00901] [EC:2.7.1.107]
113532024  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
113546965  dgkq; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
113523662  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
113544537  diacylglycerol kinase delta-like [KO:K00901] [EC:2.7.1.107]
113525843  diacylglycerol kinase beta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
113545646  diacylglycerol kinase alpha-like isoform X1 [KO:K00901] [EC:2.7.1.107]
113529631  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
113546638  phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
113524405  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
113531245  pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
113541206  phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
113526997  pld3; phospholipase D3 [KO:K16860] [EC:3.1.4.4]
113538610  pld4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
113546498  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
113542489  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113524859  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113546112  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113532930  uncharacterized protein LOC113532930 [KO:K01047] [EC:3.1.1.4]
113524724  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113543959  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113543961  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113542057  pla2g12b; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
113523962  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113543995  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113536273  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113544184  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113544185  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
113544769  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113539246  cytosolic phospholipase A2-like [KO:K16342] [EC:3.1.1.4]
113546810  cytosolic phospholipase A2-like [KO:K16342] [EC:3.1.1.4]
113533151  pla2g4c; cytosolic phospholipase A2 gamma isoform X1 [KO:K16342] [EC:3.1.1.4]
113544977  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
113545129  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
113545137  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
113547636  85/88 kDa calcium-independent phospholipase A2-like isoform X1 [KO:K16343] [EC:3.1.1.4]
113545259  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113525192  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113547666  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113545116  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113528737  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113534115  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113543699  lpcat1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113541008  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113544444  lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
113542576  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
113540402  lypla1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
113546526  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
113536149  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
113537076  patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
113537725  neuropathy target esterase-like [KO:K14676] [EC:3.1.1.5]
113535547  patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
113545179  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
113544018  chat; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
113527245  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
113526677  cAMP-regulated D2 protein-like [KO:K01049] [EC:3.1.1.7]
113539917  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
113534330  choline/ethanolamine kinase-like isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
113534349  chka; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
113527960  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
113535146  probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
113540589  choline-phosphate cytidylyltransferase A-like [KO:K00968] [EC:2.7.7.15]
113541695  choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
113541354  pcyt1b; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
113526693  choline-phosphate cytidylyltransferase A-like [KO:K00968] [EC:2.7.7.15]
113530565  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
113531994  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
113524727  ethanolamine kinase 2-like isoform X1 [KO:K00894] [EC:2.7.1.82]
113538132  etnk2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
113524299  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
113527870  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
113529998  phosphoethanolamine N-methyltransferase 3-like isoform X1 [KO:K05929] [EC:2.1.1.103]
113540638  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
113539038  pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
113536841  phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
113537026  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
113526077  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
113532863  phosphatidylserine synthase 1-like [KO:K08729] [EC:2.7.8.-]
113536339  ptdss1; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
113529441  phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
113531386  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
113527469  pgs1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
113538880  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
113525327  taz; tafazzin [KO:K13511] [EC:2.3.1.-]
113532412  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
113528539  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
113533952  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
phyp00010  Glycolysis / Gluconeogenesis
phyp00260  Glycine, serine and threonine metabolism
phyp00561  Glycerolipid metabolism
phyp00562  Inositol phosphate metabolism
phyp00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
phyp00565  Ether lipid metabolism
phyp00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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