KEGG   PATHWAY: pmua00350
Entry
pmua00350                   Pathway                                
Name
Tyrosine metabolism - Podarcis muralis (common wall lizard)
Class
Metabolism; Amino acid metabolism
Pathway map
pmua00350  Tyrosine metabolism
pmua00350

Module
pmua_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:pmua00350]
pmua_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:pmua00350]
pmua_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:pmua00350]
Other DBs
GO: 0006570
Organism
Podarcis muralis (common wall lizard) [GN:pmua]
Gene
114597608  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
114585883  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
114585884  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
114601856  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
114602047  TAT; tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
114588610  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
114588621  LOW QUALITY PROTEIN: L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
114590937  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
114588443  L-amino-acid oxidase-like isoform X1 [KO:K03334] [EC:1.4.3.2]
114586755  HPD; 4-hydroxyphenylpyruvate dioxygenase isoform X1 [KO:K00457] [EC:1.13.11.27]
114587751  HGD; LOW QUALITY PROTEIN: homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
114591596  GSTZ1; maleylacetoacetate isomerase isoform X1 [KO:K01800] [EC:5.2.1.2]
114584576  FAH; fumarylacetoacetase [KO:K01555] [EC:3.7.1.2]
114595291  TYR; tyrosinase [KO:K00505] [EC:1.14.18.1]
114599115  TH; tyrosine 3-monooxygenase [KO:K00501] [EC:1.14.16.2]
114605512  tyrosine 3-monooxygenase-like [KO:K00501] [EC:1.14.16.2]
114596563  DCT; L-dopachrome tautomerase [KO:K01827] [EC:5.3.3.12]
114587614  TYRP1; 5,6-dihydroxyindole-2-carboxylic acid oxidase [KO:K00506] [EC:1.14.18.-]
114582385  DDC; aromatic-L-amino-acid decarboxylase isoform X1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
114588914  DBH; dopamine beta-hydroxylase [KO:K00503] [EC:1.14.17.1]
114582804  PNMT; phenylethanolamine N-methyltransferase [KO:K00553] [EC:2.1.1.28]
114586245  COMT; catechol O-methyltransferase isoform X1 [KO:K00545] [EC:2.1.1.6]
114595274  transmembrane O-methyltransferase homolog [KO:K00545] [EC:2.1.1.6]
114596152  amine oxidase [flavin-containing] B-like [KO:K00274] [EC:1.4.3.4]
114596153  amine oxidase [flavin-containing] A-like [KO:K00274] [EC:1.4.3.4]
114598145  primary amine oxidase, lung isozyme-like [KO:K00276] [EC:1.4.3.21]
114581941  membrane primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
114582167  AOC2; retina-specific copper amine oxidase isoform X1 [KO:K00276] [EC:1.4.3.21]
114602234  ALDH3B1; aldehyde dehydrogenase family 3 member B1 [KO:K00129] [EC:1.2.1.5]
114591404  alcohol dehydrogenase 1A-like [KO:K13951] [EC:1.1.1.1]
114603910  alcohol dehydrogenase 1-like isoform X1 [KO:K13951] [EC:1.1.1.1]
114603912  alcohol dehydrogenase 1A [KO:K13951] [EC:1.1.1.1]
114603913  alcohol dehydrogenase 1B-like [KO:K13951] [EC:1.1.1.1]
114603914  alcohol dehydrogenase 1A-like isoform X1 [KO:K13951] [EC:1.1.1.1]
114603919  alcohol dehydrogenase 4-like [KO:K13980] [EC:1.1.1.1]
114603909  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
114593754  TPO; thyroid peroxidase [KO:K00431] [EC:1.11.1.8]
114600521  eosinophil peroxidase-like isoform X1 [KO:K00431] [EC:1.11.1.8]
114607773  aldehyde oxidase 4-like isoform X1 [KO:K00157] [EC:1.2.3.1]
114607791  AOX1; aldehyde oxidase [KO:K00157] [EC:1.2.3.1]
114584924  FAHD1; acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
114587021  MIF; macrophage migration inhibitory factor [KO:K07253] [EC:5.3.2.1]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
pmua00020  Citrate cycle (TCA cycle)
pmua00360  Phenylalanine metabolism
pmua00400  Phenylalanine, tyrosine and tryptophan biosynthesis
pmua00620  Pyruvate metabolism
pmua00650  Butanoate metabolism
KO pathway
ko00350   
LinkDB

DBGET integrated database retrieval system