KEGG   PATHWAY: pspw00230
Entry
pspw00230                   Pathway                                
Name
Purine metabolism - Paraburkholderia sprentiae
Class
Metabolism; Nucleotide metabolism
Pathway map
pspw00230  Purine metabolism
pspw00230

Module
pspw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pspw00230]
pspw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pspw00230]
pspw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pspw00230]
pspw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pspw00230]
pspw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pspw00230]
pspw_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pspw00230]
pspw_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pspw00230]
Other DBs
GO: 0006163 0042278
Organism
Paraburkholderia sprentiae [GN:pspw]
Gene
BJG93_07795  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BJG93_09565  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BJG93_11065  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BJG93_20960  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BJG93_08095  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BJG93_00145  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BJG93_08355  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
BJG93_05245  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BJG93_10325  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BJG93_15960  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BJG93_15955  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BJG93_15950  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BJG93_15480  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BJG93_15600  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BJG93_10970  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BJG93_10830  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
BJG93_00635  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
BJG93_05815  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BJG93_26390  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BJG93_24430  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
BJG93_05775  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BJG93_16935  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
BJG93_15150  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BJG93_03700  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
BJG93_03115  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BJG93_00805  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BJG93_01035  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
BJG93_10020  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
BJG93_01030  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BJG93_10015  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BJG93_26565  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
BJG93_18635  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
BJG93_26560  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
BJG93_18630  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
BJG93_26555  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
BJG93_18625  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
BJG93_03710  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
BJG93_12840  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
BJG93_01015  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BJG93_00820  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BJG93_16855  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
BJG93_15175  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BJG93_15185  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BJG93_14250  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BJG93_00830  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BJG93_01940  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BJG93_02360  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K00951] [EC:2.7.6.5]
BJG93_03185  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BJG93_11850  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BJG93_15200  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
BJG93_20760  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BJG93_01020  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BJG93_16325  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BJG93_02645  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
BJG93_28770  phosphorylase [KO:K00988] [EC:2.7.7.5 2.7.7.53]
BJG93_09830  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BJG93_29510  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BJG93_09885  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BJG93_09250  sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
BJG93_29505  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
BJG93_09255  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
BJG93_03810  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BJG93_03785  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
BJG93_03775  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
BJG93_03780  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
BJG93_03790  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BJG93_15395  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BJG93_03795  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
BJG93_15400  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
BJG93_21180  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
BJG93_09410  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BJG93_09405  urease subunit beta [KO:K01429] [EC:3.5.1.5]
BJG93_09400  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BJG93_25460  gamma-glutamyltransferase family protein [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pspw00030  Pentose phosphate pathway
pspw00220  Arginine biosynthesis
pspw00250  Alanine, aspartate and glutamate metabolism
pspw00260  Glycine, serine and threonine metabolism
pspw00340  Histidine metabolism
pspw00630  Glyoxylate and dicarboxylate metabolism
pspw00730  Thiamine metabolism
pspw00740  Riboflavin metabolism
pspw00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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