KEGG   PATHWAY: pstg00230
Entry
pstg00230                   Pathway                                
Name
Purine metabolism - Phreatobacter stygius
Class
Metabolism; Nucleotide metabolism
Pathway map
pstg00230  Purine metabolism
pstg00230

Module
pstg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pstg00230]
pstg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pstg00230]
pstg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pstg00230]
pstg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pstg00230]
pstg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pstg00230]
pstg_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pstg00230]
pstg_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pstg00230]
Other DBs
GO: 0006163 0042278
Organism
Phreatobacter stygius [GN:pstg]
Gene
E8M01_11370  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
E8M01_08915  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
E8M01_05485  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
E8M01_29750  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
E8M01_16945  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
E8M01_29925  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
E8M01_00660  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
E8M01_00675  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
E8M01_00665  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
E8M01_29930  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
E8M01_05025  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
E8M01_05030  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
E8M01_00690  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
E8M01_08710  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
E8M01_00615  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
E8M01_11265  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
E8M01_03845  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
E8M01_21685  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
E8M01_33635  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
E8M01_11355  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
E8M01_05475  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
E8M01_10985  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
E8M01_01335  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
E8M01_29035  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
E8M01_29915  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
E8M01_13950  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
E8M01_00310  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
E8M01_31620  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
E8M01_20810  FAD-binding molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
E8M01_31615  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
E8M01_06920  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
E8M01_06925  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
E8M01_06930  (2Fe-2S)-binding protein [KO:K13483]
E8M01_13400  type 1 glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
E8M01_10720  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
E8M01_24060  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
E8M01_29075  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
E8M01_19730  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
E8M01_13330  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
E8M01_29835  guanylate kinase [KO:K00942] [EC:2.7.4.8]
E8M01_22395  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
E8M01_27725  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
E8M01_22390  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
E8M01_33930  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
E8M01_20745  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
E8M01_30020  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
E8M01_34790  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
E8M01_28015  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
E8M01_13360  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8M01_22285  CYTH domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8M01_07260  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
E8M01_04740  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
E8M01_14950  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
E8M01_21475  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
E8M01_19240  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
E8M01_33215  adenylate kinase [KO:K00939] [EC:2.7.4.3]
E8M01_31505  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
E8M01_31405  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
E8M01_17615  metallophosphoesterase-domain-containing protein [KO:K03651] [EC:3.1.4.53]
E8M01_12780  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
E8M01_12775  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
E8M01_17965  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
E8M01_20595  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
E8M01_31625  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
E8M01_18580  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
E8M01_02780  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
E8M01_22580  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
E8M01_26445  allantoinase [KO:K01466] [EC:3.5.2.5]
E8M01_31995  chitin deacetylase [KO:K16842] [EC:3.5.2.5]
E8M01_18575  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
E8M01_31600  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
E8M01_18600  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
E8M01_23695  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
E8M01_33840  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
E8M01_33845  urease subunit beta [KO:K01429] [EC:3.5.1.5]
E8M01_33860  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
E8M01_15855  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pstg00030  Pentose phosphate pathway
pstg00220  Arginine biosynthesis
pstg00250  Alanine, aspartate and glutamate metabolism
pstg00260  Glycine, serine and threonine metabolism
pstg00340  Histidine metabolism
pstg00630  Glyoxylate and dicarboxylate metabolism
pstg00730  Thiamine metabolism
pstg00740  Riboflavin metabolism
pstg00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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