KEGG   PATHWAY: ptao00564
Entry
ptao00564                   Pathway                                
Name
Glycerophospholipid metabolism - Phyllopteryx taeniolatus (common seadragon)
Class
Metabolism; Lipid metabolism
Pathway map
ptao00564  Glycerophospholipid metabolism
ptao00564

Module
ptao_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:ptao00564]
ptao_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:ptao00564]
ptao_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:ptao00564]
Other DBs
GO: 0006650
Organism
Phyllopteryx taeniolatus (common seadragon) [GN:ptao]
Gene
133483576  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
133479012  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
133479707  gpd1c; glycerol-3-phosphate dehydrogenase 1c [KO:K00006] [EC:1.1.1.8]
133488023  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
133479497  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
133469755  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
133475166  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
133475115  agpat9l; glycerol-3-phosphate acyltransferase 3-like isoform X1 [KO:K13506] [EC:2.3.1.15]
133475534  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
133490057  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 [KO:K13509] [EC:2.3.1.51]
133485824  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
133486716  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
133485444  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
133488074  lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
133479906  mboat1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
133488142  mboat2a; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
133468232  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
133468650  gnpat2; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
133468877  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
133488804  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
133465273  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
133465838  ppap2d; phosphatidic acid phosphatase type 2D [KO:K01080] [EC:3.1.3.4]
133480525  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
133480710  plpp2b; phospholipid phosphatase 2b [KO:K01080] [EC:3.1.3.4]
133475210  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
133476300  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
133488350  phospholipid phosphatase 2-like isoform X1 [KO:K01080] [EC:3.1.3.4]
133470380  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
133484047  zgc:123305 isoform X1 [KO:K15728] [EC:3.1.3.4]
133474305  lpin1a; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
133468649  lpin1b; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
133488444  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
133486167  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
133475153  plpp5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
133476531  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
133482655  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
133483351  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
133483956  dgkab; diacylglycerol kinase, alpha b isoform X1 [KO:K00901] [EC:2.7.1.107]
133484905  diacylglycerol kinase theta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
133471862  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
133479081  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
133472462  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
133485818  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
133486494  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
133486621  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
133471763  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
133483930  cept1b; choline/ethanolaminephosphotransferase 1b [KO:K13644] [EC:2.7.8.1 2.7.8.2]
133470472  phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
133467443  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
133487840  pld1a; phospholipase D1a isoform X1 [KO:K01115] [EC:3.1.4.4]
133484348  pld7; 5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
133487618  5'-3' exonuclease PLD4 isoform X1 [KO:K16860] [EC:3.1.4.4]
133482030  pld3; 5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
133477693  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
133476859  pla2g12a; group XIIA secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
133477458  group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
133465165  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
133466552  pla2g10; group 10 secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
133486042  pla2g12b; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
133474634  phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
133485567  pla2g4f.1; cytosolic phospholipase A2 beta isoform X1 [KO:K16342] [EC:3.1.1.4]
133485850  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
133480602  cytosolic phospholipase A2-like isoform X1 [KO:K16342] [EC:3.1.1.4]
133476814  pla2g6; LOW QUALITY PROTEIN: 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
133468158  phospholipase B1, membrane-associated-like isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133487563  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133468667  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133488205  plb1; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133485236  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
133480874  plaat1l; phospholipase A and acyltransferase 1 isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
133471086  lpcat1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
133479379  lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
133474179  lpcat2; lysophosphatidylcholine acyltransferase 2 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
133472433  lpcat4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
133479248  lpcat3; lysophospholipid acyltransferase 5 isoform X1 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
133470002  acyl-protein thioesterase 1-like [KO:K06128] [EC:3.1.1.5]
133477694  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
133470643  lypla2; acyl-protein thioesterase 2 isoform X1 [KO:K06130] [EC:3.1.1.5]
133489784  pnpla7a; patatin-like phospholipase domain-containing protein 7a isoform X1 [KO:K14676] [EC:3.1.1.5]
133475440  pnpla7b; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
133476258  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
133467897  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
133486107  chata; choline O-acetyltransferase isoform X1 [KO:K00623] [EC:2.3.1.6]
133469148  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
133472949  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
133477822  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
133478128  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
133469467  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
133465866  phospho1; probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
133488547  pcyt1aa; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
133470157  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
133467331  pcyt1bb; phosphate cytidylyltransferase 1B, choline b [KO:K00968] [EC:2.7.7.15]
133467975  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
133483822  etnk2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
133478244  ethanolamine kinase 1-like isoform X1 [KO:K00894] [EC:2.7.1.82]
133471725  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
133476467  pcyt2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
133466285  ethanolamine-phosphate cytidylyltransferase-like isoform X1 [KO:K00967] [EC:2.7.7.14]
133485106  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
133472800  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
133469068  pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
133474704  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
133474840  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
133486408  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
133479880  ptdss1a; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
133478016  ptdss2; phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
133490286  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
133469257  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
133485887  crls1; cardiolipin synthase (CMP-forming) isoform X1 [KO:K08744] [EC:2.7.8.41]
133480795  tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
133468366  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
133466034  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
133479057  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
ptao00010  Glycolysis / Gluconeogenesis
ptao00260  Glycine, serine and threonine metabolism
ptao00561  Glycerolipid metabolism
ptao00562  Inositol phosphate metabolism
ptao00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
ptao00565  Ether lipid metabolism
ptao00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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