KEGG   PATHWAY: raa00230
Entry
raa00230                    Pathway                                
Name
Purine metabolism - Rahnella aquatilis HX2
Class
Metabolism; Nucleotide metabolism
Pathway map
raa00230  Purine metabolism
raa00230

Module
raa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:raa00230]
raa_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:raa00230]
raa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:raa00230]
raa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:raa00230]
raa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:raa00230]
raa_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:raa00230]
raa_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:raa00230]
Other DBs
GO: 0006163 0042278
Organism
Rahnella aquatilis HX2 [GN:raa]
Gene
Q7S_02880  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Q7S_01300  nudE; adenosine nucleotide hydrolase NudE [KO:K08312] [EC:3.6.1.-]
Q7S_19455  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Q7S_16005  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Q7S_11535  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Q7S_05920  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Q7S_20925  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Q7S_16515  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Q7S_14575  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Q7S_17230  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Q7S_16510  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
Q7S_16590  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
Q7S_16585  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
Q7S_16455  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Q7S_14750  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Q7S_20920  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Q7S_16705  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Q7S_03150  surE; 5'(3')-nucleotidase/polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Q7S_16075  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
Q7S_01290  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
Q7S_16665  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
Q7S_19450  purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Q7S_17130  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Q7S_03415  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Q7S_05215  ribosylpyrimidine nucleosidase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
Q7S_18730  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Q7S_05050  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Q7S_04965  ndk; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
Q7S_19375  inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
Q7S_17890  dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
Q7S_04540  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Q7S_11215  xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
Q7S_11210  xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
Q7S_05055  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
Q7S_02610  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
Q7S_18925  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
Q7S_11225  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Q7S_22195  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
Q7S_03555  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
Q7S_06185  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
Q7S_06180  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
Q7S_03550  nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
Q7S_02580  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Q7S_09480  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Q7S_18360  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Q7S_06040  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
Q7S_22205  bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Q7S_16530  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Q7S_21685  guanosine pentaphosphate phosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Q7S_16295  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Q7S_03030  relA; (p)ppGpp synthetase I/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
Q7S_21590  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
Q7S_15955  3',5'-cyclic-nucleotide phosphodiesterase [KO:K01120] [EC:3.1.4.17]
Q7S_02155  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Q7S_11060  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Q7S_07775  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Q7S_04010  hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
Q7S_16790  adenine deaminase [KO:K01486] [EC:3.5.4.2]
Q7S_02230  cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Q7S_16675  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
Q7S_03035  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
Q7S_02890  cyclic 3',5'-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
Q7S_17535  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Q7S_11130  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Q7S_19190  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
Q7S_03120  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Q7S_03115  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Q7S_03110  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Q7S_20625  FAD dependent oxidoreductase [KO:K16839] [EC:1.14.13.113]
Q7S_04450  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
Q7S_04445  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
Q7S_04380  hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Q7S_01475  allantoinase [KO:K01466] [EC:3.5.2.5]
Q7S_04385  urate catabolism protein [KO:K16842] [EC:3.5.2.5]
Q7S_04440  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
Q7S_01495  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
Q7S_04435  class V aminotransferase [KO:K00839] [EC:2.6.1.112]
Q7S_01490  hypothetical protein [KO:K14977] [EC:3.5.3.26]
Q7S_01445  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Q7S_01500  ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
Q7S_04395  amidase [KO:K22601] [EC:2.1.3.5]
Q7S_04405  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Q7S_01520  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Q7S_19790  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
raa00030  Pentose phosphate pathway
raa00220  Arginine biosynthesis
raa00250  Alanine, aspartate and glutamate metabolism
raa00260  Glycine, serine and threonine metabolism
raa00340  Histidine metabolism
raa00630  Glyoxylate and dicarboxylate metabolism
raa00730  Thiamine metabolism
raa00740  Riboflavin metabolism
raa00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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