KEGG   PATHWAY: rbw00230
Entry
rbw00230                    Pathway                                
Name
Purine metabolism - Rhizobium brockwellii
Class
Metabolism; Nucleotide metabolism
Pathway map
rbw00230  Purine metabolism
rbw00230

Module
rbw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rbw00230]
rbw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rbw00230]
rbw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rbw00230]
rbw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rbw00230]
rbw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rbw00230]
rbw_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rbw00230]
rbw_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rbw00230]
Other DBs
GO: 0006163 0042278
Organism
Rhizobium brockwellii [GN:rbw]
Gene
RLCC275e_22970  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
RLCC275e_18680  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
RLCC275e_15660  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
RLCC275e_06005  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
RLCC275e_02800  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
RLCC275e_06255  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
RLCC275e_10985  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
RLCC275e_10945  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
RLCC275e_10955  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
RLCC275e_06260  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
RLCC275e_18295  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
RLCC275e_18290  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
RLCC275e_10940  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
RLCC275e_17655  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
RLCC275e_10910  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
RLCC275e_21780  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
RLCC275e_15725  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
RLCC275e_18450  LysM peptidoglycan-binding domain-containing protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
RLCC275e_08335  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RLCC275e_22940  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
RLCC275e_15645  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
RLCC275e_19815  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
RLCC275e_02270  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
RLCC275e_06180  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
RLCC275e_00020  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
RLCC275e_07850  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
RLCC275e_16210  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
RLCC275e_16215  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
RLCC275e_24745  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
RLCC275e_09645  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
RLCC275e_24750  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
RLCC275e_24755  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
RLCC275e_23150  type 1 glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
RLCC275e_23435  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
RLCC275e_20695  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
RLCC275e_16250  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
RLCC275e_06090  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
RLCC275e_07835  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
RLCC275e_19440  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
RLCC275e_19435  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
RLCC275e_08285  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
RLCC275e_05890  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
RLCC275e_05800  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
RLCC275e_02245  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RLCC275e_06280  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RLCC275e_28560  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_28605  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_29920  tetratricopeptide repeat protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_04125  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_04875  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_06290  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_10075  tetratricopeptide repeat protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_10330  tetratricopeptide repeat protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_10375  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_12130  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_12245  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
RLCC275e_12675  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
RLCC275e_12680  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_13600  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_13660  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_14230  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_18625  tetratricopeptide repeat protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_18730  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_18735  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_19315  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_19430  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_17570  tetratricopeptide repeat protein [KO:K01768] [EC:4.6.1.1]
RLCC275e_17245  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
RLCC275e_22965  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
RLCC275e_05645  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
RLCC275e_08140  adenine deaminase [KO:K01486] [EC:3.5.4.2]
RLCC275e_16065  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
RLCC275e_17690  adenine deaminase [KO:K01486] [EC:3.5.4.2]
RLCC275e_20550  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
RLCC275e_07920  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
RLCC275e_17955  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
RLCC275e_07450  adenylate kinase [KO:K00939] [EC:2.7.4.3]
RLCC275e_09320  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
RLCC275e_04500  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
RLCC275e_04505  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
RLCC275e_28970  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
RLCC275e_03240  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
RLCC275e_16280  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
RLCC275e_24140  hydrogenase expression protein HupH [KO:K16841] [EC:5.1.99.3]
RLCC275e_14760  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
RLCC275e_23745  amidohydrolase family protein [KO:K01466] [EC:3.5.2.5]
RLCC275e_16300  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
RLCC275e_29745  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
RLCC275e_16285  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
RLCC275e_17035  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
RLCC275e_17060  urease subunit beta [KO:K01429] [EC:3.5.1.5]
RLCC275e_17070  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rbw00030  Pentose phosphate pathway
rbw00220  Arginine biosynthesis
rbw00250  Alanine, aspartate and glutamate metabolism
rbw00260  Glycine, serine and threonine metabolism
rbw00340  Histidine metabolism
rbw00630  Glyoxylate and dicarboxylate metabolism
rbw00730  Thiamine metabolism
rbw00740  Riboflavin metabolism
rbw00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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