KEGG   PATHWAY: sdu00564
Entry
sdu00564                    Pathway                                
Name
Glycerophospholipid metabolism - Seriola dumerili (greater amberjack)
Class
Metabolism; Lipid metabolism
Pathway map
sdu00564  Glycerophospholipid metabolism
sdu00564

Module
sdu_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:sdu00564]
sdu_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:sdu00564]
sdu_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:sdu00564]
Other DBs
GO: 0006650
Organism
Seriola dumerili (greater amberjack) [GN:sdu]
Gene
111217340  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
111227760  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
111232722  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
111233571  gpd1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
111232773  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
111219961  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
111237756  glycerol-3-phosphate acyltransferase 2, mitochondrial-like [KO:K00629] [EC:2.3.1.15]
111238026  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
111230237  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
111234204  glycerol-3-phosphate acyltransferase 4-like [KO:K13506] [EC:2.3.1.15]
111236535  glycerol-3-phosphate acyltransferase 3-like isoform X1 [KO:K13506] [EC:2.3.1.15]
111220809  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
111218173  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
111234410  1-acyl-sn-glycerol-3-phosphate acyltransferase delta-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
111234451  1-acyl-sn-glycerol-3-phosphate acyltransferase delta-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
111235238  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
111225380  lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
111227708  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
111231651  membrane-bound O-acyltransferase domain-containing protein 2-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]
111226095  mboat2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
111216410  dihydroxyacetone phosphate acyltransferase-like isoform X1 [KO:K00649] [EC:2.3.1.42]
111239366  gnpat; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
111219537  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
111239868  plpp1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
111230845  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
111226173  plpp2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
111232177  phospholipid phosphatase 2-like isoform X1 [KO:K01080] [EC:3.1.3.4]
111227306  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
111226319  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
111229337  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
111229054  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
111221861  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
111219735  phosphatidate phosphatase LPIN1-like isoform X1 [KO:K15728] [EC:3.1.3.4]
111237853  lpin2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
111236254  lpin1; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
111231233  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
111220707  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
111237709  phospholipid phosphatase 5-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
111224631  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
111216798  LOW QUALITY PROTEIN: diacylglycerol kinase delta-like [KO:K00901] [EC:2.7.1.107]
111217946  dgke; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
111218180  diacylglycerol kinase beta-like [KO:K00901] [EC:2.7.1.107]
111221482  diacylglycerol kinase alpha-like [KO:K00901] [EC:2.7.1.107]
111222430  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
111233712  LOW QUALITY PROTEIN: diacylglycerol kinase zeta-like [KO:K00901] [EC:2.7.1.107]
111232464  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
111233493  dgkq; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
111234964  diacylglycerol kinase alpha-like [KO:K00901] [EC:2.7.1.107]
111237958  dgkh; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
111233446  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
111225032  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
111219428  cept1; choline/ethanolaminephosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
111225732  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
111238302  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
111234313  phospholipase D2-like [KO:K01115] [EC:3.1.4.4]
111225576  pld4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
111216991  phospholipase D3-like [KO:K16860] [EC:3.1.4.4]
111222526  phosphatidylcholine-sterol acyltransferase-like [KO:K00650] [EC:2.3.1.43]
111217959  group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
111217708  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111217832  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111220656  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
111236607  group XIIA secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
111236628  group XIIA secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111227744  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111227753  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
111227221  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111237503  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111217737  pla2g4c; LOW QUALITY PROTEIN: cytosolic phospholipase A2 gamma [KO:K16342] [EC:3.1.1.4]
111232269  pla2g4a; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
111216730  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
111225492  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111216413  LOW QUALITY PROTEIN: phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111238803  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111232455  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111232445  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111232453  HRAS-like suppressor 2 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111226148  retinoic acid receptor responder protein 3-like isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111219107  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
111227743  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
111233198  lysophosphatidylcholine acyltransferase 1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
111238596  lpcat4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
111230069  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
111237893  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
111222488  group XV phospholipase A2-like [KO:K06129] [EC:3.1.1.5]
111220858  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
111238928  patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
111229295  pnpla6; neuropathy target esterase isoform X1 [KO:K14676] [EC:3.1.1.5]
111228859  pnpla7; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
111239486  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
111219604  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
111235159  chat; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
111224923  cAMP-regulated D2 protein-like [KO:K01049] [EC:3.1.1.7]
111223642  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
111222494  choline kinase alpha-like [KO:K14156] [EC:2.7.1.32 2.7.1.82]
111228401  choline/ethanolamine kinase-like [KO:K14156] [EC:2.7.1.32 2.7.1.82]
111217605  phospho1; phosphoethanolamine/phosphocholine phosphatase isoform X1 [KO:K06124] [EC:3.1.3.75]
111220061  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
111228991  pcyt1a; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
111237228  pcyt1b; choline-phosphate cytidylyltransferase B [KO:K00968] [EC:2.7.7.15]
111234454  choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
111216350  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
111224595  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
111221703  ethanolamine kinase 1-like isoform X1 [KO:K00894] [EC:2.7.1.82]
111229674  ethanolamine kinase 1-like [KO:K00894] [EC:2.7.1.82]
111226997  ethanolamine-phosphate cytidylyltransferase-like isoform X1 [KO:K00967] [EC:2.7.7.14]
111229283  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
111232752  phosphoethanolamine N-methyltransferase 3-like isoform X1 [KO:K05929] [EC:2.1.1.103]
111231620  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
111220104  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
111229224  phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
111228020  phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
111218105  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
111223165  phosphatidylserine synthase 1-like [KO:K08729] [EC:2.7.8.-]
111236829  phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
111229645  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
111238746  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
111220148  pgs1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
111227420  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
111237646  taz; tafazzin [KO:K13511] [EC:2.3.1.-]
111239627  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
111238864  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
111229986  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
sdu00010  Glycolysis / Gluconeogenesis
sdu00260  Glycine, serine and threonine metabolism
sdu00561  Glycerolipid metabolism
sdu00562  Inositol phosphate metabolism
sdu00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
sdu00565  Ether lipid metabolism
sdu00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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