KEGG   PATHWAY: slal00564
Entry
slal00564                   Pathway                                
Name
Glycerophospholipid metabolism - Seriola lalandi dorsalis (Yellowtail amberjack)
Class
Metabolism; Lipid metabolism
Pathway map
slal00564  Glycerophospholipid metabolism
slal00564

Module
slal_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:slal00564]
slal_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:slal00564]
slal_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:slal00564]
Other DBs
GO: 0006650
Organism
Seriola lalandi dorsalis (Yellowtail amberjack) [GN:slal]
Gene
111655095  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
111664173  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
111665236  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
111655011  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
111670330  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
111657120  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
111661004  glycerol-3-phosphate acyltransferase 2, mitochondrial-like [KO:K00629] [EC:2.3.1.15]
111654935  gpat3; glycerol-3-phosphate acyltransferase 3 isoform X1 [KO:K13506] [EC:2.3.1.15]
111649139  glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
111645044  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
111655170  glycerol-3-phosphate acyltransferase 4-like isoform X1 [KO:K13506] [EC:2.3.1.15]
111666849  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
111652397  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
111658907  LOW QUALITY PROTEIN: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
111656692  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
111651013  lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
111644761  mboat2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
111645196  membrane-bound O-acyltransferase domain-containing protein 2-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]
111657216  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
111672757  dihydroxyacetone phosphate acyltransferase-like [KO:K00649] [EC:2.3.1.42]
111672611  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
111667088  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
111654295  phospholipid phosphatase 2-like [KO:K01080] [EC:3.1.3.4]
111666537  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
111656803  LOW QUALITY PROTEIN: phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
111653698  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
111665198  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
111645125  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
111665514  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
111673079  phospholipid phosphatase 2-like [KO:K01080] [EC:3.1.3.4]
111657010  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
111667792  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
111659124  phosphatidate phosphatase LPIN1-like isoform X1 [KO:K15728] [EC:3.1.3.4]
111656605  lpin2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
111672594  lpin1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
111658913  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
111661022  phospholipid phosphatase 5-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
111644569  dgkh; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
111646691  dgkd; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
111665608  dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
111649346  diacylglycerol kinase zeta-like [KO:K00901] [EC:2.7.1.107]
111667116  dgkk; diacylglycerol kinase kappa isoform X1 [KO:K00901] [EC:2.7.1.107]
111654103  diacylglycerol kinase beta-like [KO:K00901] [EC:2.7.1.107]
111649629  diacylglycerol kinase zeta-like [KO:K00901] [EC:2.7.1.107]
111667773  dgka; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
111669099  dgki; LOW QUALITY PROTEIN: diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
111661959  diacylglycerol kinase alpha-like [KO:K00901] [EC:2.7.1.107]
111670345  dgkz; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
111655464  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
111644542  dgkb; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
111656498  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
111662327  cept1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
111647269  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
111665871  phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
111653988  phospholipase D2-like [KO:K01115] [EC:3.1.4.4]
111652454  pld4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
111662210  phospholipase D3-like [KO:K16860] [EC:3.1.4.4]
111658753  phosphatidylcholine-sterol acyltransferase-like isoform X1 [KO:K00650] [EC:2.3.1.43]
111660403  group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
111644948  group 3 secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
111650662  uncharacterized protein LOC111650662 [KO:K01047] [EC:3.1.1.4]
111660614  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111666007  uncharacterized protein LOC111666007 [KO:K01047] [EC:3.1.1.4]
111671169  group XIIA secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111671190  uncharacterized protein LOC111671190 [KO:K01047] [EC:3.1.1.4]
111655941  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111645028  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111645029  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111658897  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
111645380  pla2g4a; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
111669721  pla2g4c; cytosolic phospholipase A2 gamma [KO:K16342] [EC:3.1.1.4]
111673436  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
111651022  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111661530  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111659872  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111672653  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111655836  retinoic acid receptor responder protein 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111646783  retinoic acid receptor responder protein 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111655783  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
111649514  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
111671489  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
111673069  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
111661668  lysophospholipid acyltransferase LPCAT4-like [KO:K13512] [EC:2.3.1.23 2.3.1.-]
111669906  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
111656592  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
111658751  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
111645626  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
111652827  pnpla6; neuropathy target esterase isoform X1 [KO:K14676] [EC:3.1.1.5]
111652989  patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
111647951  patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
111672778  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
111660222  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
111654634  chat; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
111656836  cAMP-regulated D2 protein-like [KO:K01049] [EC:3.1.1.7]
111668006  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
111658758  choline kinase alpha-like isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
111671240  choline/ethanolamine kinase-like [KO:K14156] [EC:2.7.1.32 2.7.1.82]
111658418  probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
111657148  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
111671101  pcyt1a; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
111662974  pcyt1b; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
111666197  choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
111672501  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
111667272  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
111668656  etnk2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
111650458  ethanolamine kinase 1-like isoform X1 [KO:K00894] [EC:2.7.1.82]
111666727  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
111657795  ethanolamine-phosphate cytidylyltransferase-like isoform X1 [KO:K00967] [EC:2.7.7.14]
111655797  phosphoethanolamine N-methyltransferase 3-like isoform X1 [KO:K05929] [EC:2.1.1.103]
111649906  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
111656406  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
111660905  phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
111648005  phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
111652105  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
111652784  phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
111659236  phosphatidylserine synthase 1-like [KO:K08729] [EC:2.7.8.-]
111650416  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
111670236  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
111673512  pgs1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
111644599  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
111673373  taz; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
111661368  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
111653121  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
111669884  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
slal00010  Glycolysis / Gluconeogenesis
slal00260  Glycine, serine and threonine metabolism
slal00561  Glycerolipid metabolism
slal00562  Inositol phosphate metabolism
slal00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
slal00565  Ether lipid metabolism
slal00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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