KEGG   PATHWAY: sspl00270
Entry
sspl00270                   Pathway                                
Name
Cysteine and methionine metabolism - Salvia splendens (scarlet sage)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
sspl00270  Cysteine and methionine metabolism
sspl00270

Module
sspl_M00021  Cysteine biosynthesis, serine => cysteine [PATH:sspl00270]
sspl_M00034  Methionine salvage pathway [PATH:sspl00270]
sspl_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:sspl00270]
Other DBs
GO: 0006534 0006555
Organism
Salvia splendens (scarlet sage) [GN:sspl]
Gene
121756360  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121785770  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121800058  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
121759324  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121773407  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121790745  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121804641  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121808280  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
121796286  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
121756353  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
121759473  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
121775211  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
121790104  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
121777331  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
121805422  cysteine synthase, chloroplastic/chromoplastic-like [KO:K01738] [EC:2.5.1.47]
121808716  cysteine synthase [KO:K01738] [EC:2.5.1.47]
121809370  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
121809637  cysteine synthase, chloroplastic/chromoplastic-like isoform X1 [KO:K01738] [EC:2.5.1.47]
121783916  cysteine synthase [KO:K01738] [EC:2.5.1.47]
121798141  L-3-cyanoalanine synthase 2, mitochondrial-like isoform X1 [KO:K13034] [EC:2.5.1.47 4.4.1.9]
121795227  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
121771846  cystathionine beta-lyase, chloroplastic-like isoform X1 [KO:K01760] [EC:4.4.1.13]
121749250  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
121768521  cystathionine beta-lyase, chloroplastic-like isoform X1 [KO:K01760] [EC:4.4.1.13]
121801448  homocysteine S-methyltransferase 3-like isoform X1 [KO:K00547] [EC:2.1.1.10]
121778187  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
121793506  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
121767139  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
121781056  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
121755682  homocysteine S-methyltransferase 2 [KO:K00547] [EC:2.1.1.10]
121785906  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
121786987  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like isoform X1 [KO:K00549] [EC:2.1.1.14]
121787142  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
121761268  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
121748316  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
121748975  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
121765382  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
121765396  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
121741102  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like isoform X1 [KO:K00549] [EC:2.1.1.14]
121799024  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
121799029  S-adenosylmethionine synthase 3-like isoform X1 [KO:K00789] [EC:2.5.1.6]
121748341  S-adenosylmethionine synthase 5-like [KO:K00789] [EC:2.5.1.6]
121762619  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
121765028  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
121752082  S-adenosylmethionine synthase 5 [KO:K00789] [EC:2.5.1.6]
121795483  S-adenosylmethionine synthase 3-like isoform X1 [KO:K00789] [EC:2.5.1.6]
121795484  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
121754172  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
121754297  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
121769800  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121769949  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
121798306  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
121771113  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
121786488  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121767780  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
121795929  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
121797081  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
121769098  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121794936  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121801168  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
121801286  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121778591  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
121806684  spermidine synthase 1-like isoform X1 [KO:K00797] [EC:2.5.1.16]
121794742  spermidine synthase 1 isoform X1 [KO:K00797] [EC:2.5.1.16]
121766528  spermidine synthase 1-like isoform X1 [KO:K00797] [EC:2.5.1.16]
121781074  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
121758965  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
121807355  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
121754187  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
121762291  5'-methylthioadenosine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
121765485  5'-methylthioadenosine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
121760983  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
121742240  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
121805303  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
121810040  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
121771799  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
121802280  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 isoform X1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
121806324  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
121767549  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
121784870  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like isoform X1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121759559  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121759569  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121794118  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121782944  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
121803600  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
121780199  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
121782605  methionine aminotransferase-like [KO:K23977] [EC:2.6.1.117]
121756020  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
121756428  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
121758245  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
121772289  probable aminotransferase TAT2 isoform X1 [KO:K00815] [EC:2.6.1.5]
121805018  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
121740889  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
121808555  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
121810483  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
121810810  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
121800265  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
121797177  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
121756487  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
121770755  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
121759451  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
121753528  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
121769209  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
121784865  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
121798687  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
121811507  DNA (cytosine-5)-methyltransferase CMT1-like [KO:K00558] [EC:2.1.1.37]
121744734  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
121787364  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
121761358  DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
121763334  DNA (cytosine-5)-methyltransferase CMT2-like isoform X1 [KO:K00558] [EC:2.1.1.37]
121791838  LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
121779961  DNA (cytosine-5)-methyltransferase CMT2-like isoform X1 [KO:K00558] [EC:2.1.1.37]
121780938  DNA (cytosine-5)-methyltransferase CMT2-like isoform X1 [KO:K00558] [EC:2.1.1.37]
121792424  uncharacterized protein LOC121792424 [KO:K17398] [EC:2.1.1.37]
121749172  uncharacterized protein LOC121749172 [KO:K17398] [EC:2.1.1.37]
121792329  uncharacterized protein LOC121792329 [KO:K17398] [EC:2.1.1.37]
121798913  uncharacterized protein LOC121798913 [KO:K17398] [EC:2.1.1.37]
121799847  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
121805028  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
121796106  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
121809415  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
121769147  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
121769895  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121799936  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121750705  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121778735  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121793774  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121767164  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
121758032  1-aminocyclopropane-1-carboxylate synthase-like [KO:K01762] [EC:4.4.1.14]
121786483  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
121801136  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
121774046  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
121749286  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
121776474  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
121794072  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
121752722  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
121754871  1-aminocyclopropane-1-carboxylate synthase-like [KO:K01762] [EC:4.4.1.14]
121783914  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
121758094  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
121786058  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
121746222  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
121773658  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
121747826  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
121776181  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
121803055  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
121803202  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
121791655  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
121751490  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
121740832  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
121754211  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
121769383  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
121798427  aspartokinase 1, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
121749021  aspartokinase 2, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
121750888  aspartokinase 2, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
121780850  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
121794556  aspartokinase 1, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
121779889  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
121806498  bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
121781858  bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic-like isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
121782254  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
121772422  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
121759757  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
121755533  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
121769342  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
121805236  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
121750529  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
121809753  homoserine kinase-like [KO:K00872] [EC:2.7.1.39]
121769486  cystathionine gamma-synthase 1, chloroplastic-like [KO:K27857] [EC:2.5.1.160]
121769894  cystathionine gamma-synthase 1, chloroplastic-like [KO:K27857] [EC:2.5.1.160]
121759989  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
121774995  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
121775737  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
121762694  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
121765848  branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
121765850  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
121745175  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121745899  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121787183  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121775811  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121806484  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121742206  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
121785504  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
121745442  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
121742399  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
121762255  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
121765496  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
121744554  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
121804808  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
121741463  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
121808470  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
121804567  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
121807215  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
121785040  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
121752423  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
121758449  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
121804652  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
121806483  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
121753918  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
121799317  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
121795675  L-lactate dehydrogenase A-like [KO:K00016] [EC:1.1.1.27]
121785332  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial-like [KO:K05396] [EC:4.4.1.15]
121785333  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
121786061  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
121800439  D-cysteine desulfhydrase 2, mitochondrial-like isoform X1 [KO:K05396] [EC:4.4.1.15]
121789344  putative D-cysteine desulfhydrase 1, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121762339  putative D-cysteine desulfhydrase 1, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121766169  putative D-cysteine desulfhydrase 1, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
121794513  D-cysteine desulfhydrase 2, mitochondrial-like isoform X1 [KO:K05396] [EC:4.4.1.15]
121756826  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
121746386  L-cysteine desulfhydrase-like [KO:K22207] [EC:4.4.1.28]
121753395  L-cysteine desulfhydrase-like [KO:K22207] [EC:4.4.1.28]
121811310  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
121745115  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
121789165  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
121802209  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
121802431  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
121751942  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
121806229  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
121808572  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
121785006  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
121786070  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
121773209  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
121773289  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
121774232  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
121761888  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
121775998  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
121802610  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
121777284  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
121803934  malate dehydrogenase-like [KO:K00026] [EC:1.1.1.37]
121805371  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
121806703  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
121780294  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
121782869  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
121798960  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121758546  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121772217  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121804842  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121794123  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121753619  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121782285  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121769264  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
121774905  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
121788396  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
121777016  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01102  O-Phospho-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
sspl00010  Glycolysis / Gluconeogenesis
sspl00250  Alanine, aspartate and glutamate metabolism
sspl00260  Glycine, serine and threonine metabolism
sspl00290  Valine, leucine and isoleucine biosynthesis
sspl00430  Taurine and hypotaurine metabolism
sspl00480  Glutathione metabolism
sspl00620  Pyruvate metabolism
sspl00640  Propanoate metabolism
sspl00770  Pantothenate and CoA biosynthesis
sspl00900  Terpenoid backbone biosynthesis
sspl00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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