KEGG   PATHWAY: tdw00564
Entry
tdw00564                    Pathway                                
Name
Glycerophospholipid metabolism - Triplophysa dalaica
Class
Metabolism; Lipid metabolism
Pathway map
tdw00564  Glycerophospholipid metabolism
tdw00564

Module
tdw_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:tdw00564]
tdw_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:tdw00564]
tdw_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:tdw00564]
Other DBs
GO: 0006650
Organism
Triplophysa dalaica [GN:tdw]
Gene
130429571  gpd1b; glycerol-3-phosphate dehydrogenase 1b [KO:K00006] [EC:1.1.1.8]
130415512  gpd1c; glycerol-3-phosphate dehydrogenase 1c isoform X1 [KO:K00006] [EC:1.1.1.8]
130433349  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
130440052  gpd1a; glycerol-3-phosphate dehydrogenase 1a [KO:K00006] [EC:1.1.1.8]
130424578  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
130439372  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
130440151  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
130411488  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
130439774  glycerol-3-phosphate acyltransferase 4-like isoform X1 [KO:K13506] [EC:2.3.1.15]
130408487  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
130418888  agpat9l; glycerol-3-phosphate acyltransferase 3-like isoform X1 [KO:K13506] [EC:2.3.1.15]
130408383  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
130431294  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130439297  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130431377  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
130431573  lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
130436922  mboat2a; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130433547  mboat1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130434044  mboat2b; lysophospholipid acyltransferase 2b isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130434224  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
130434890  gnpat2; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
130439101  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
130412214  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
130430739  plpp2b; phospholipid phosphatase 2b [KO:K01080] [EC:3.1.3.4]
130407303  phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
130426205  ppap2d; phosphatidic acid phosphatase type 2D [KO:K01080] [EC:3.1.3.4]
130417656  plpp2a; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
130434160  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
130418184  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
130424678  zgc:123305 [KO:K15728] [EC:3.1.3.4]
130424730  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
130417137  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
130434149  lpin1b; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
130411730  plpp5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130431727  plpp4; phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130420883  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
130437814  diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
130414097  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
130424746  dgke; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
130409038  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
130426741  dgkza; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
130418708  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
130427338  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
130427354  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
130428416  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
130420549  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
130430503  cept1b; choline/ethanolaminephosphotransferase 1b isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
130439872  cept1a; choline/ethanolaminephosphotransferase 1a [KO:K13644] [EC:2.7.8.1 2.7.8.2]
130413463  pld1b; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
130417393  pld1a; phospholipase D1a [KO:K01115] [EC:3.1.4.4]
130427416  si:ch211-168k14.2; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
130419032  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
130436048  pld3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
130436415  5'-3' exonuclease PLD4 [KO:K16860] [EC:3.1.4.4]
130413842  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
130411662  pla2g3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130429191  proca1; uncharacterized protein proca1 [KO:K01047] [EC:3.1.1.4]
130411978  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
130412462  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130406871  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
130431868  pla2g12b; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
130426033  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130419606  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
130436426  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
130436427  cytosolic phospholipase A2 delta-like [KO:K16342] [EC:3.1.1.4]
130436836  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
130436837  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
130436949  cytosolic phospholipase A2 delta-like [KO:K16342] [EC:3.1.1.4]
130434099  pla2g4ab; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
130418307  pla2g4aa; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
130418764  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
130419168  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
130429729  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
130436939  plb1; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130433950  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130438103  rarres3l; retinoic acid receptor responder 3-like isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130438191  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130418229  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130429590  lpcat2; lysophosphatidylcholine acyltransferase 2 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130433012  lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130416002  lpcat1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130435752  lysophospholipid acyltransferase LPCAT4-like [KO:K13512] [EC:2.3.1.23 2.3.1.-]
130435834  lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
130433491  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
130428108  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
130414474  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
130415272  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
130413201  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
130407436  pnpla7a; patatin-like phospholipase domain-containing protein 7a isoform X1 [KO:K14676] [EC:3.1.1.5]
130419093  pnpla7b; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
130434163  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
130431417  chata; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
130438699  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
130424931  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
130436004  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
130435379  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
130425612  phospho1; probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
130435769  pcyt1ab; phosphate cytidylyltransferase 1A, choline b isoform X1 [KO:K00968] [EC:2.7.7.15]
130413178  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
130407830  pcyt1bb; phosphate cytidylyltransferase 1B, choline b [KO:K00968] [EC:2.7.7.15]
130418438  pcyt1aa; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
130409051  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
130420524  etnk1; ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
130413940  zgc:113516; ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
130410155  etnk2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
130430553  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
130437802  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
130418305  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
130438877  pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
130418808  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
130419052  cds2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
130427653  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
130433288  ptdss1a; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
130414149  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
130418986  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
130439378  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
130437240  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
130409176  tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
130434201  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
130426423  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
130432790  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
tdw00010  Glycolysis / Gluconeogenesis
tdw00260  Glycine, serine and threonine metabolism
tdw00561  Glycerolipid metabolism
tdw00562  Inositol phosphate metabolism
tdw00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
tdw00565  Ether lipid metabolism
tdw00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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