KEGG   PATHWAY: thw00630
Entry
thw00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thioclava nitratireducens
Class
Metabolism; Carbohydrate metabolism
Pathway map
thw00630  Glyoxylate and dicarboxylate metabolism
thw00630

Module
thw_M00621  Glycine cleavage system [PATH:thw00630]
thw_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:thw00630]
Other DBs
GO: 0046487 0043648
Organism
Thioclava nitratireducens [GN:thw]
Gene
BMG03_11930  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
BMG03_16685  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BMG03_09505  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BMG03_13445  malate synthase G [KO:K01638] [EC:2.3.3.9]
BMG03_06655  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BMG03_03940  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BMG03_14360  citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BMG03_12295  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BMG03_18515  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMG03_16905  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMG03_17205  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMG03_00645  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMG03_00750  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMG03_09210  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BMG03_17210  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
BMG03_08540  (R)-hydratase [KO:K17865] [EC:4.2.1.55]
BMG03_18280  crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
BMG03_16295  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
BMG03_18270  protein meaA [KO:K14447] [EC:5.4.99.63]
BMG03_06685  hypothetical protein [KO:K14449] [EC:4.2.1.148]
BMG03_17130  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
BMG03_06670  CoA ester lyase [KO:K14451] [EC:3.1.2.30]
BMG03_13590  acetyl/propionyl-CoA carboxylase subuit alpha [KO:K01965] [EC:6.4.1.3]
BMG03_13610  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
BMG03_13580  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
BMG03_14725  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
BMG03_14720  2-hydroxy-acid oxidase [KO:K11472] [EC:1.1.99.14]
BMG03_14715  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BMG03_05960  catalase [KO:K03781] [EC:1.11.1.6]
BMG03_16360  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
BMG03_15900  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BMG03_08165  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
BMG03_16740  phosphatase [KO:K01091] [EC:3.1.3.18]
BMG03_03910  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
BMG03_10935  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BMG03_10895  rbcL; ribulose-bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
BMG03_10900  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
BMG03_12215  type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
BMG03_16460  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BMG03_06880  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BMG03_01700  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BMG03_17365  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BMG03_06955  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
BMG03_06945  gcvT; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
BMG03_07570  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BMG03_08915  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BMG03_06615  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BMG03_06950  glycine cleavage system protein H [KO:K02437]
BMG03_04860  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BMG03_14445  hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
BMG03_05525  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BMG03_17455  hypothetical protein [KO:K00126] [EC:1.17.1.9]
BMG03_04230  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
BMG03_17465  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
BMG03_04225  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
BMG03_17470  formate dehydrogenase [KO:K00124]
BMG03_04220  formate dehydrogenase [KO:K00124]
BMG03_17475  formate dehydrogenase subunit gamma [KO:K00127]
BMG03_04215  formate dehydrogenase subunit gamma [KO:K00127]
BMG03_09375  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
BMG03_07095  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
thw00010  Glycolysis / Gluconeogenesis
thw00020  Citrate cycle (TCA cycle)
thw00030  Pentose phosphate pathway
thw00053  Ascorbate and aldarate metabolism
thw00071  Fatty acid degradation
thw00230  Purine metabolism
thw00250  Alanine, aspartate and glutamate metabolism
thw00260  Glycine, serine and threonine metabolism
thw00620  Pyruvate metabolism
thw00710  Carbon fixation by Calvin cycle
thw00750  Vitamin B6 metabolism
thw00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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