KEGG   PATHWAY: thw00230
Entry
thw00230                    Pathway                                
Name
Purine metabolism - Thioclava nitratireducens
Class
Metabolism; Nucleotide metabolism
Pathway map
thw00230  Purine metabolism
thw00230

Module
thw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:thw00230]
thw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:thw00230]
thw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:thw00230]
thw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:thw00230]
thw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:thw00230]
thw_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:thw00230]
thw_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:thw00230]
Other DBs
GO: 0006163 0042278
Organism
Thioclava nitratireducens [GN:thw]
Gene
BMG03_10235  hypothetical protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BMG03_17325  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BMG03_10855  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BMG03_07310  phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
BMG03_07285  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BMG03_07020  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BMG03_07890  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BMG03_03000  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
BMG03_08635  phosphoribosylformylglycinamidine synthase [KO:K23264] [EC:6.3.5.3]
BMG03_08640  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BMG03_07895  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BMG03_11665  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BMG03_11660  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BMG03_08630  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BMG03_08470  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BMG03_18665  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BMG03_03700  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BMG03_11890  hypothetical protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
BMG03_14375  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BMG03_18245  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
BMG03_16580  polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BMG03_11510  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BMG03_10135  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
BMG03_12400  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BMG03_01995  non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BMG03_14290  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BMG03_15935  xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
BMG03_15940  xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BMG03_06175  xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
BMG03_06180  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
BMG03_06185  (2Fe-2S)-binding protein [KO:K13483]
BMG03_10515  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
BMG03_07080  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BMG03_11410  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BMG03_14255  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BMG03_09450  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BMG03_14080  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BMG03_09445  class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BMG03_07950  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BMG03_02230  hypothetical protein [KO:K06952] [EC:3.1.3.89]
BMG03_00445  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BMG03_11390  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMG03_13560  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMG03_07200  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BMG03_18775  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BMG03_18770  adenine deaminase [KO:K01486] [EC:3.5.4.2]
BMG03_06235  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BMG03_07420  hypothetical protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BMG03_13715  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
BMG03_16680  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMG03_03860  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMG03_10635  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
BMG03_16180  adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BMG03_16175  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
BMG03_07595  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BMG03_02770  OHCU decarboxylase [KO:K16842] [EC:3.5.2.5]
BMG03_04290  Zn-dependent hydrolase [KO:K02083] [EC:3.5.3.9]
BMG03_02775  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
BMG03_02780  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BMG03_15015  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BMG03_15020  urease subunit beta [KO:K01429] [EC:3.5.1.5]
BMG03_15030  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
thw00030  Pentose phosphate pathway
thw00220  Arginine biosynthesis
thw00250  Alanine, aspartate and glutamate metabolism
thw00260  Glycine, serine and threonine metabolism
thw00340  Histidine metabolism
thw00630  Glyoxylate and dicarboxylate metabolism
thw00730  Thiamine metabolism
thw00740  Riboflavin metabolism
thw00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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