KEGG   PATHWAY: pfor00564
Entry
pfor00564                   Pathway                                
Name
Glycerophospholipid metabolism - Poecilia formosa (Amazon molly)
Class
Metabolism; Lipid metabolism
Pathway map
pfor00564  Glycerophospholipid metabolism
pfor00564

Module
pfor_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:pfor00564]
pfor_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:pfor00564]
pfor_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:pfor00564]
Other DBs
GO: 0006650
Organism
Poecilia formosa (Amazon molly) [GN:pfor]
Gene
103129400  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
103130056  [KO:K01115] [EC:3.1.4.4]
103130346  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X2 [KO:K01613] [EC:4.1.1.65]
103130577  [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103131210  dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
103131253  ept1; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
103132023  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
103132139  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
103133098  dgke; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
103133329  [KO:K01047] [EC:3.1.1.4]
103133524  sgms1; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
103133743  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
103133880  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
103134058  [KO:K22697] [EC:3.1.4.62]
103134062  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
103134095  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
103134127  pla2g12b; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
103134501  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
103134553  gpd1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
103134697  cept1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
103134889  [KO:K00981] [EC:2.7.7.41]
103134901  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
103135123  ptdss1; phosphatidylserine synthase 1 isoform X3 [KO:K08729] [EC:2.7.8.-]
103135184  [KO:K14621] [EC:3.1.1.4 3.1.1.5]
103135224  pcyt1b; choline-phosphate cytidylyltransferase B isoform X2 [KO:K00968] [EC:2.7.7.15]
103135687  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
103135897  [KO:K13509] [EC:2.3.1.51]
103136093  pld4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
103136648  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
103136761  lpcat3; lysophospholipid acyltransferase 5 isoform X2 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
103136891  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
103136915  [KO:K05929] [EC:2.1.1.103]
103136998  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103137069  plpp3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
103137254  pla2g4a; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
103138102  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103138294  pld3; phospholipase D3 [KO:K16860] [EC:3.1.4.4]
103139133  [KO:K00901] [EC:2.7.1.107]
103139187  [KO:K00006] [EC:1.1.1.8]
103139536  [KO:K15728] [EC:3.1.3.4]
103140044  [KO:K01080] [EC:3.1.3.4]
103140972  [KO:K00967] [EC:2.7.7.14]
103141376  [KO:K01047] [EC:3.1.1.4]
103141377  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103141503  [KO:K00968] [EC:2.7.7.15]
103141504  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
103141771  [KO:K01080] [EC:3.1.3.4]
103141911  [KO:K14676] [EC:3.1.1.5]
103142150  phospho1; phosphoethanolamine/phosphocholine phosphatase isoform X1 [KO:K06124] [EC:3.1.3.75]
103142275  [KO:K00623] [EC:2.3.1.6]
103142320  samd8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:3.1.4.62]
103142460  [KO:K14156] [EC:2.7.1.32 2.7.1.82]
103142507  [KO:K06129] [EC:3.1.1.5]
103142508  [KO:K00650] [EC:2.3.1.43]
103142527  [KO:K06129] [EC:3.1.1.5]
103142604  [KO:K01080] [EC:3.1.3.4]
103142701  plpp1; phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
103142830  [KO:K15728] [EC:3.1.3.4]
103143400  etnppl; ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
103143453  lypla2; acyl-protein thioesterase 2 isoform X1 [KO:K06130] [EC:3.1.1.5]
103143765  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
103143796  [KO:K01047] [EC:3.1.1.4]
103143902  sgms2; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
103143911  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103144095  etnk2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
103144110  [KO:K00649] [EC:2.3.1.42]
103144111  lpin1; phosphatidate phosphatase LPIN1 isoform X2 [KO:K15728] [EC:3.1.3.4]
103144295  [KO:K00901] [EC:2.7.1.107]
103144496  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
103144577  [KO:K01047] [EC:3.1.1.4]
103144630  lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
103144646  dgkk; LOW QUALITY PROTEIN: diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
103145154  pgs1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X2 [KO:K00995] [EC:2.7.8.5]
103145637  [KO:K01115] [EC:3.1.4.4]
103145845  plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103145862  [KO:K00629] [EC:2.3.1.15]
103145885  [KO:K13506] [EC:2.3.1.15]
103146032  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103146101  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
103146324  [KO:K01047] [EC:3.1.1.4]
103146532  pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
103146572  plpp2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
103146717  [KO:K00981] [EC:2.7.7.41]
103147010  pcyt1a; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
103147272  mboat2; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103147571  [KO:K00894] [EC:2.7.1.82]
103147649  [KO:K14676] [EC:3.1.1.5]
103147747  chat; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
103147818  [KO:K00006] [EC:1.1.1.8]
103148039  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
103148529  proca1; protein PROCA1 [KO:K01047] [EC:3.1.1.4]
103148623  dgkz; diacylglycerol kinase zeta isoform X3 [KO:K00901] [EC:2.7.1.107]
103148729  pnpla6; neuropathy target esterase isoform X1 [KO:K14676] [EC:3.1.1.5]
103148856  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
103148980  [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103149022  [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103149064  [KO:K04714] [EC:2.7.8.27 3.1.4.62]
103149264  pla2g4c; cytosolic phospholipase A2 gamma [KO:K16342] [EC:3.1.1.4]
103149300  [KO:K16860] [EC:3.1.4.4]
103149421  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
103149797  lypla1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
103149806  [KO:K15728] [EC:3.1.3.4]
103149904  [KO:K00901] [EC:2.7.1.107]
103150082  lpcat1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103150246  [KO:K13506] [EC:2.3.1.15]
103150302  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
103150345  crls1; cardiolipin synthase (CMP-forming) isoform X1 [KO:K08744] [EC:2.7.8.41]
103150515  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
103152002  [KO:K01080] [EC:3.1.3.4]
103152153  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
103152258  [KO:K08729] [EC:2.7.8.-]
103152963  dgkd; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
103153217  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
103153392  [KO:K06124] [EC:3.1.3.75]
103153464  taz; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
103154151  [KO:K01080] [EC:3.1.3.4]
103154831  pla2g6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
103154934  lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
103154957  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
103155573  [KO:K01047] [EC:3.1.1.4]
103155711  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
103155771  [KO:K00894] [EC:2.7.1.82]
103155836  gnpat; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
103156580  [KO:K00901] [EC:2.7.1.107]
103156582  [KO:K00901] [EC:2.7.1.107]
103156920  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
pfor00010  Glycolysis / Gluconeogenesis
pfor00260  Glycine, serine and threonine metabolism
pfor00561  Glycerolipid metabolism
pfor00562  Inositol phosphate metabolism
pfor00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
pfor00565  Ether lipid metabolism
pfor00620  Pyruvate metabolism
KO pathway
ko00564   

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