KEGG   PATHWAY: phi03083
Entry
phi03083                    Pathway                                
Name
Polycomb repressive complex - Pseudopodoces humilis (Tibetan ground-tit)
Class
Genetic Information Processing; Chromosome
Pathway map
phi03083  Polycomb repressive complex
phi03083

Organism
Pseudopodoces humilis (Tibetan ground-tit) [GN:phi]
Gene
102099669  CSNK2B; casein kinase II subunit beta [KO:K03115]
102099878  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
102099930  EZH2; histone-lysine N-methyltransferase EZH2 isoform X3 [KO:K11430] [EC:2.1.1.356]
102099959  AEBP2; zinc finger protein AEBP2 [KO:K17452]
102100070  AUTS2; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
102100079  WDR5; WD repeat-containing protein 5 [KO:K14963]
102100212  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
102100793  ASXL1; putative Polycomb group protein ASXL1 isoform X1 [KO:K11471]
102100832  EED; polycomb protein EED [KO:K11462]
102101010  PHF1; PHD finger protein 1 [KO:K11467]
102101050  RBBP4; histone-binding protein RBBP4 isoform X1 [KO:K10752]
102101532  JARID2; protein Jumonji [KO:K11478]
102101749  [KO:K11479] [EC:2.7.11.1]
102102208  MAX; protein max isoform X4 [KO:K04453]
102102768  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
102102865  PCGF6; polycomb group RING finger protein 6 isoform X1 [KO:K11470]
102103022  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
102103208  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 isoform X1 [KO:K24387]
102103544  E2F6; transcription factor E2F6 isoform X1 [KO:K09390]
102103576  EZH1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
102103680  PHC3; polyhomeotic-like protein 3 isoform X1 [KO:K11458]
102103796  CREBBP; CREB-binding protein isoform X2 [KO:K04498] [EC:2.3.1.48]
102103938  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
102103970  MTF2; metal-response element-binding transcription factor 2 isoform X2 [KO:K11485]
102104046  SFMBT2; scm-like with four MBT domains protein 2 [KO:K26269]
102104149  PCGF5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
102104382  [KO:K11459]
102104559  TEX10; testis-expressed sequence 10 protein isoform X1 [KO:K14827]
102104750  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
102105070  FOXK2; forkhead box protein K2 isoform X1 [KO:K09404]
102105103  BCOR; BCL-6 corepressor isoform X1 [KO:K23215]
102105787  YAF2; YY1-associated factor 2 [KO:K11468]
102105937  SUZ12; polycomb protein SUZ12 [KO:K11463]
102106059  BCORL1; BCL-6 corepressor-like protein 1 [KO:K26199]
102106577  SCMH1; polycomb protein SCMH1 isoform X1 [KO:K11461]
102106598  UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X2 [KO:K06689] [EC:2.3.2.23]
102106680  FOXK1; forkhead box protein K1 [KO:K09404]
102107483  UBE2D2; ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
102107511  PCGF3; polycomb group RING finger protein 3 isoform X1 [KO:K11488]
102107539  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 [KO:K08588] [EC:3.4.19.12]
102107700  PCGF1; polycomb group RING finger protein 1 [KO:K11487]
102107746  ASXL2; putative Polycomb group protein ASXL2 isoform X1 [KO:K11471]
102107897  USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [KO:K11844] [EC:3.4.19.12]
102108102  PHF19; PHD finger protein 19 [KO:K11486]
102108423  PHC2; polyhomeotic-like protein 2 [KO:K11457]
102108602  PCGF2; polycomb group RING finger protein 2 [KO:K11460]
102108874  MGA; MAX gene-associated protein isoform X1 [KO:K23399]
102109144  CBX2; chromobox protein homolog 2 [KO:K11451]
102109322  CBX8; chromobox protein homolog 8 isoform X2 [KO:K11455]
102109503  CBX4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
102110016  RYBP; RING1 and YY1-binding protein isoform X1 [KO:K11469]
102110123  USP45; ubiquitin carboxyl-terminal hydrolase 45 [KO:K11844] [EC:3.4.19.12]
102110620  SCML2; sex comb on midleg-like protein 2 [KO:K11465]
102110682  ASXL3; putative Polycomb group protein ASXL3 [KO:K11471]
102110853  PHC1; polyhomeotic-like protein 1 isoform X1 [KO:K11456]
102111184  [KO:K14966]
102111386  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
102111680  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
102111848  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
102112796  MBD5; methyl-CpG-binding domain protein 5 [KO:K23219]
102112943  OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
102113066  FBRSL1; fibrosin-1-like protein isoform X1 [KO:K26254]
102113164  RBBP7; LOW QUALITY PROTEIN: histone-binding protein RBBP7 [KO:K11659]
102113341  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 [KO:K24387]
102113371  USP7; ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
102113870  KDM2B; lysine-specific demethylase 2B isoform X4 [KO:K10276] [EC:1.14.11.27]
102114137  [KO:K24387]
102114164  CBX3; chromobox protein homolog 3 isoform X1 [KO:K11586]
102114217  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 isoform X1 [KO:K24387]
102114222  YY1; transcriptional repressor protein YY1 [KO:K09201]
102114250  KDM2A; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
102114437  CBX6; chromobox protein homolog 6 isoform X1 [KO:K11453]
102114612  CBX7; chromobox protein homolog 7 isoform X2 [KO:K11454]
102114725  [KO:K26260]
106628624  [KO:K26259]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   

DBGET integrated database retrieval system