KEGG   PATHWAY: ppam00330
Entry
ppam00330                   Pathway                                
Name
Arginine and proline metabolism - Pteronotus mesoamericanus (Parnell's mustached bat)
Class
Metabolism; Amino acid metabolism
Pathway map
ppam00330  Arginine and proline metabolism
ppam00330

Module
ppam_M00015  Proline biosynthesis, glutamate => proline [PATH:ppam00330]
ppam_M00047  Creatine pathway [PATH:ppam00330]
ppam_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ppam00330]
ppam_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:ppam00330]
ppam_M00970  Proline degradation, proline => glutamate [PATH:ppam00330]
ppam_M00972  Proline metabolism [PATH:ppam00330]
Other DBs
GO: 0006525 0006560
Organism
Pteronotus mesoamericanus (Parnell's mustached bat) [GN:ppam]
Gene
129063837  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
129063957  CKMT1A; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
129064652  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
129065254  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
129065255  MAOA; amine oxidase [flavin-containing] A isoform X1 [KO:K00274] [EC:1.4.3.4]
129065768  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
129065946  ARG2; arginase-2, mitochondrial isoform X1 [KO:K01476] [EC:3.5.3.1]
129066223  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
129066699  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
129067628  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
129067702  AMD1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
129067776  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
129068359  CARNS1; carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
129068768  ALDH3A2; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
129069034  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
129069096  [KO:K00802] [EC:2.5.1.22]
129069887  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
129070278  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
129070830  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
129072182  SAT2; thialysine N-epsilon-acetyltransferase isoform X1 [KO:K00657] [EC:2.3.1.57]
129072630  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
129072884  PYCR2; pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
129074654  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
129075294  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
129075585  AGMAT; agmatinase, mitochondrial [KO:K27001]
129075616  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
129075659  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
129076007  [KO:K00802] [EC:2.5.1.22]
129076037  [KO:K00274] [EC:1.4.3.4]
129076941  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
129076947  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
129077065  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
129077099  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
129077241  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
129077277  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
129077544  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
129078776  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
129078923  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
129079409  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
129080071  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
129082069  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
129082856  CKM; creatine kinase M-type [KO:K27382]
129082929  ALDH16A1; aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
129083102  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
129083866  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
129084364  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
129086238  PRODH; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
129086660  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
129086742  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
129086753  NOS3; nitric oxide synthase, endothelial [KO:K13242] [EC:1.14.13.39]
129087308  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
129087355  NOS1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
129087442  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ppam00020  Citrate cycle (TCA cycle)
ppam00220  Arginine biosynthesis
ppam00250  Alanine, aspartate and glutamate metabolism
ppam00260  Glycine, serine and threonine metabolism
ppam00270  Cysteine and methionine metabolism
ppam00310  Lysine degradation
ppam00410  beta-Alanine metabolism
ppam00470  D-Amino acid metabolism
ppam00480  Glutathione metabolism
ppam00630  Glyoxylate and dicarboxylate metabolism
ppam00650  Butanoate metabolism
ppam00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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