KEGG   PATHWAY: pre00230
Entry
pre00230                    Pathway                                
Name
Purine metabolism - Metapseudomonas resinovorans
Class
Metabolism; Nucleotide metabolism
Pathway map
pre00230  Purine metabolism
pre00230

Module
pre_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pre00230]
pre_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pre00230]
pre_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pre00230]
pre_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pre00230]
pre_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pre00230]
pre_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pre00230]
pre_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pre00230]
Other DBs
GO: 0006163 0042278
Organism
Metapseudomonas resinovorans [GN:pre]
Gene
PCA10_00690  nrdJa; ribonucleotide reductase subunit NrdJa [KO:K00525] [EC:1.17.4.1]
PCA10_02810  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
PCA10_05200  [KO:K16841] [EC:5.1.99.3]
PCA10_05370  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
PCA10_08250  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
PCA10_09480  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
PCA10_10480  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
PCA10_10490  cysNC; sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
PCA10_11410  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
PCA10_11580  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
PCA10_11590  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
PCA10_11640  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
PCA10_12300  [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PCA10_16920  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
PCA10_17790  [KO:K14977] [EC:3.5.3.26]
PCA10_17980  nrdB; ribonucleoside-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
PCA10_17990  nrdA; ribonucleoside-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
PCA10_19230  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
PCA10_19240  [KO:K13485] [EC:4.1.1.97]
PCA10_19250  [KO:K16842] [EC:3.5.2.5]
PCA10_19260  [KO:K07127] [EC:3.5.2.17]
PCA10_19290  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
PCA10_19310  xdhB; xanthine dehydrogenase large subunit [KO:K13482] [EC:1.17.1.4]
PCA10_19320  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
PCA10_20190  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
PCA10_20750  [KO:K01129] [EC:3.1.5.1]
PCA10_21510  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
PCA10_22450  [KO:K01951] [EC:6.3.5.2]
PCA10_24150  [KO:K16842] [EC:3.5.2.5]
PCA10_25050  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
PCA10_30630  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
PCA10_32210  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
PCA10_32920  [KO:K01081] [EC:3.1.3.5]
PCA10_36140  [KO:K01487] [EC:3.5.4.3]
PCA10_36150  [KO:K07127] [EC:3.5.2.17]
PCA10_36160  [KO:K07127] [EC:3.5.2.17]
PCA10_36190  [KO:K13485] [EC:4.1.1.97]
PCA10_38500  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
PCA10_39440  cyaB; adenylyl cyclase CyaB [KO:K01768] [EC:4.6.1.1]
PCA10_43770  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
PCA10_44070  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
PCA10_44520  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
PCA10_44530  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
PCA10_44570  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
PCA10_44580  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
PCA10_45060  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PCA10_45710  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
PCA10_46360  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
PCA10_48110  [KO:K00760] [EC:2.4.2.8]
PCA10_48310  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PCA10_49540  [KO:K01951] [EC:6.3.5.2]
PCA10_50300  [KO:K21053] [EC:3.5.4.2]
PCA10_51000  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
PCA10_51010  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
PCA10_51140  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
PCA10_51160  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
PCA10_51170  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
PCA10_51760  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
PCA10_52060  cpdA; 3',5'-cyclic AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
PCA10_52080  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
PCA10_53920  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
PCA10_53950  nudE; ADP compound hydrolase [KO:K08312] [EC:3.6.1.-]
PCA10_53960  [KO:K20881] [EC:3.1.3.-]
PCA10_54560  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
PCA10_54830  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
PCA10_55060  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
PCA10_55240  algC; phosphomannomutase/phosphoglucomutase AlgC [KO:K15778] [EC:5.4.2.8 5.4.2.2]
PCA10_55330  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
PCA10_55350  spoT; (p)ppGpp synthase/hydrolase SpoT [KO:K01139] [EC:2.7.6.5 3.1.7.2]
PCA10_55820  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
PCA10_55830  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pre00030  Pentose phosphate pathway
pre00220  Arginine biosynthesis
pre00250  Alanine, aspartate and glutamate metabolism
pre00260  Glycine, serine and threonine metabolism
pre00340  Histidine metabolism
pre00630  Glyoxylate and dicarboxylate metabolism
pre00730  Thiamine metabolism
pre00740  Riboflavin metabolism
pre00790  Folate biosynthesis
KO pathway
ko00230   

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