KEGG   PATHWAY: prg00230
Entry
prg00230                    Pathway                                
Name
Purine metabolism - Providencia rettgeri
Class
Metabolism; Nucleotide metabolism
Pathway map
prg00230  Purine metabolism
prg00230

Module
prg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:prg00230]
prg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:prg00230]
prg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:prg00230]
prg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:prg00230]
prg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:prg00230]
Other DBs
GO: 0006163 0042278
Organism
Providencia rettgeri [GN:prg]
Gene
RB151_000800  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
RB151_001750  purB_1; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
RB151_002190  arcC2; Carbamate kinase 2 [KO:K00926] [EC:2.7.2.2]
RB151_003160  spoT; Bifunctional (p)ppGpp synthase/hydrolase SpoT [KO:K01139] [EC:2.7.6.5 3.1.7.2]
RB151_003180  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
RB151_004210  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
RB151_004220  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
RB151_005310  rihB_1; Pyrimidine-specific ribonucleoside hydrolase RihB [KO:K25589]
RB151_006040  rihB_2; Pyrimidine-specific ribonucleoside hydrolase RihB [KO:K25589]
RB151_006340  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
RB151_006350  deoD; Purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
RB151_006520  yjjX; Non-canonical purine NTP phosphatase [KO:K01529]
RB151_006990  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
RB151_007960  guaD_1; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
RB151_008820  ureA_1; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
RB151_008830  ureB_1; Urease subunit beta [KO:K01429] [EC:3.5.1.5]
RB151_008840  ureC_1; Urease subunit alpha [KO:K01428] [EC:3.5.1.5]
RB151_009530  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
RB151_009600  yfkN_1; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
RB151_009870  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
RB151_010190  yfiH; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
RB151_010450  nrdF2; Ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
RB151_010460  nrdE; Ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
RB151_013130  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
RB151_018870  hyuC; Hydantoin utilization protein C [KO:K02083] [EC:3.5.3.9]
RB151_020460  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
RB151_021890  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
RB151_023020  add2; Aminodeoxyfutalosine deaminase [KO:K01488] [EC:3.5.4.4]
RB151_024330  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
RB151_024340  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
RB151_024540  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
RB151_024650  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
RB151_024660  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
RB151_024690  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RB151_025270  purB_2; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
RB151_025360  [KO:K05873] [EC:4.6.1.1]
RB151_025430  yhcR; Endonuclease YhcR precursor [KO:K01081] [EC:3.1.3.5]
RB151_026430  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
RB151_026440  nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
RB151_026750  yfbR_2; 5'-deoxynucleotidase YfbR [KO:K08722] [EC:3.1.3.89]
RB151_026910  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
RB151_027490  [KO:K22879] [EC:1.14.13.113]
RB151_027910  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
RB151_028400  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
RB151_033470  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
RB151_033480  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
RB151_033650  yfkN_2; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
RB151_033750  gsk; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
RB151_033780  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
RB151_033830  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
RB151_033980  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
RB151_034000  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
RB151_034020  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
RB151_034270  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
RB151_034480  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
RB151_034650  ade2; Adenine deaminase 2 [KO:K01486] [EC:3.5.4.2]
RB151_034880  surE_1; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RB151_034930  cysC; Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
RB151_034940  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
RB151_034950  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
RB151_036000  apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
RB151_036090  cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
RB151_036100  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
RB151_036570  ureA_2; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
RB151_036580  ureB_2; Urease subunit beta [KO:K01429] [EC:3.5.1.5]
RB151_036590  ureC_2; Urease subunit alpha [KO:K01428] [EC:3.5.1.5]
RB151_036770  surE_2; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RB151_040810  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
RB151_041570  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
RB151_041970  cyaA; Adenylate cyclase [KO:K05851] [EC:4.6.1.1]
RB151_042240  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RB151_044490  punA; Purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
RB151_P104548  hiuH; 5-hydroxyisourate hydrolase precursor,hydroxyisourate hydrolase,hydroxyisourate hydrolase,HIUase/Transthyretin family [KO:K07127] [EC:3.5.2.17]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
prg00030  Pentose phosphate pathway
prg00220  Arginine biosynthesis
prg00250  Alanine, aspartate and glutamate metabolism
prg00260  Glycine, serine and threonine metabolism
prg00340  Histidine metabolism
prg00630  Glyoxylate and dicarboxylate metabolism
prg00730  Thiamine metabolism
prg00740  Riboflavin metabolism
prg00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system