KEGG   PATHWAY: psom00053
Entry
psom00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Papaver somniferum (opium poppy)
Class
Metabolism; Carbohydrate metabolism
Pathway map
psom00053  Ascorbate and aldarate metabolism
psom00053

Module
psom_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:psom00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Papaver somniferum (opium poppy) [GN:psom]
Gene
113280215  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
113290028  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
113300198  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
113281781  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
113343078  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
113275836  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
113326815  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
113332494  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
113291734  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
113358220  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
113323893  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
113345802  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
113348064  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
113348066  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
113354042  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
113349309  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
113298276  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
113303246  aldo-keto reductase family 4 member C10-like isoform X1 [KO:K00002] [EC:1.1.1.2]
113310344  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
113320822  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
113310979  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
113323519  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
113327844  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113340946  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113342608  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113298738  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113313591  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113357463  probable L-gulonolactone oxidase 4 [KO:K00103] [EC:1.1.3.8]
113361107  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113348225  L-gulonolactone oxidase 3-like isoform X1 [KO:K00103] [EC:1.1.3.8]
113348226  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
113349135  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
113352362  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
113318033  GDP-mannose 3,5-epimerase 1-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
113350016  GDP-mannose 3,5-epimerase 1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
113360896  GDP-mannose 3,5-epimerase 1-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
113303517  GDP-L-galactose phosphorylase 1 [KO:K14190] [EC:2.7.7.69]
113288020  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
113275533  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
113282078  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
113288098  inositol monophosphatase 3-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
113302809  inositol monophosphatase 3-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
113308035  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
113333373  L-galactose dehydrogenase-like [KO:K17744] [EC:1.1.1.316]
113347404  L-galactose dehydrogenase-like [KO:K17744] [EC:1.1.1.316]
113322103  L-galactono-1,4-lactone dehydrogenase, mitochondrial-like [KO:K00225] [EC:1.3.2.3]
113331949  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
113282912  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
113296678  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
113304905  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
113318778  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
113275212  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
113347496  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
113349944  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
113293294  D-galacturonate reductase-like [KO:K19642] [EC:1.1.1.365]
113360647  D-galacturonate reductase-like [KO:K19642] [EC:1.1.1.365]
113300090  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
113310213  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
113321954  monodehydroascorbate reductase-like [KO:K08232] [EC:1.6.5.4]
113299232  monodehydroascorbate reductase, chloroplastic/mitochondrial-like [KO:K08232] [EC:1.6.5.4]
113319008  monodehydroascorbate reductase 4, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
113358378  monodehydroascorbate reductase, chloroplastic/mitochondrial-like [KO:K08232] [EC:1.6.5.4]
113290889  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
113321825  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
113346337  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
113288942  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
113309651  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
113330609  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
113282817  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
113357184  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
113356406  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
113361130  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
113314260  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113322673  glutathione S-transferase DHAR2-like isoform X1 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113322725  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113282063  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113310919  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113307676  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113275549  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
113311037  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
113311038  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
113309220  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
113322601  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
113324432  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
113324433  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
113310010  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
113321946  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
113310926  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
113310064  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
113321997  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
113358394  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
113320634  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
113335531  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
113328381  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
113346343  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
113289286  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
113313787  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
113340968  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
113276422  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
113297914  aldehyde dehydrogenase family 2 member B7, mitochondrial-like isoform X1 [KO:K00128] [EC:1.2.1.3]
113314097  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
113315326  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
113333532  aldehyde dehydrogenase family 2 member B4, mitochondrial-like isoform X1 [KO:K00128] [EC:1.2.1.3]
113282497  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
113355794  aldehyde dehydrogenase family 2 member B4, mitochondrial-like isoform X1 [KO:K00128] [EC:1.2.1.3]
113356410  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
113328159  aldehyde dehydrogenase family 7 member B4-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
113337233  aldehyde dehydrogenase family 7 member B4-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
psom00020  Citrate cycle (TCA cycle)
psom00040  Pentose and glucuronate interconversions
psom00051  Fructose and mannose metabolism
psom00520  Amino sugar and nucleotide sugar metabolism
psom00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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