KEGG   PATHWAY: ptr00240
Entry
ptr00240                    Pathway                                
Name
Pyrimidine metabolism - Pan troglodytes (chimpanzee)
Class
Metabolism; Nucleotide metabolism
Pathway map
ptr00240  Pyrimidine metabolism
ptr00240

Module
ptr_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:ptr00240]
ptr_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:ptr00240]
ptr_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:ptr00240]
ptr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ptr00240]
ptr_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:ptr00240]
Other DBs
GO: 0006220 0006213
Organism
Pan troglodytes (chimpanzee) [GN:ptr]
Gene
100533953  NME1; nucleoside diphosphate kinase A isoform X1 [KO:K00940] [EC:2.7.4.6]
100611890  NME4; nucleoside diphosphate kinase, mitochondrial isoform X1 [KO:K00940] [EC:2.7.4.6]
100614135  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X4 [KO:K01510] [EC:3.6.1.5]
104008182  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
107969275  [KO:K00940] [EC:2.7.4.6]
107971131  CTPS2; CTP synthase 2 isoform X1 [KO:K01937] [EC:6.3.4.2]
450706  NT5C2; cytosolic purine 5'-nucleotidase isoform X8 [KO:K01081] [EC:3.1.3.5]
450974  RRM1; ribonucleoside-diphosphate reductase large subunit isoform X1 [KO:K10807] [EC:1.17.4.1]
453027  ENTPD5; nucleoside diphosphate phosphatase ENTPD5 isoform X2 [KO:K01511] [EC:3.6.1.6]
454144  TK2; thymidine kinase 2, mitochondrial isoform X2 [KO:K00857] [EC:2.7.1.21]
454232  DHODH; dihydroorotate dehydrogenase (quinone), mitochondrial isoform X1 [KO:K00254] [EC:1.3.5.2]
454474  NT5M; 5'(3')-deoxyribonucleotidase, mitochondrial isoform X5 [KO:K01081] [EC:3.1.3.5]
456837  CMPK1; UMP-CMP kinase [KO:K13800] [EC:2.7.4.14]
457047  DPYD; dihydropyrimidine dehydrogenase [NADP(+)] isoform X2 [KO:K00207] [EC:1.3.1.2]
457498  NME7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
458146  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 isoform X2 [KO:K01511] [EC:3.6.1.6]
458424  UCKL1; uridine-cytidine kinase-like 1 [KO:K00876] [EC:2.7.1.48]
458941  TYMP; thymidine phosphorylase [KO:K00758] [EC:2.4.2.4]
459005  CMPK2; UMP-CMP kinase 2, mitochondrial [KO:K13809] [EC:2.7.4.14]
459024  RRM2; ribonucleoside-diphosphate reductase subunit M2 isoform X3 [KO:K10808] [EC:1.17.4.1]
460286  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
460343  NME6; nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
460644  UMPS; uridine 5'-monophosphate synthase isoform X2 [KO:K13421] [EC:2.4.2.10 4.1.1.23]
461273  DCK; deoxycytidine kinase isoform X1 [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
461620  DCTD; deoxycytidylate deaminase isoform X1 [KO:K01493] [EC:3.5.4.12]
462864  NT5E; 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
463000  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
463002  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
464056  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
464330  DPYS; dihydropyrimidinase isoform X1 [KO:K01464] [EC:3.5.2.2]
465056  NUDT2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
467675  DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1 [KO:K01520] [EC:3.6.1.23]
467867  NME3; nucleoside diphosphate kinase 3 isoform X1 [KO:K00940] [EC:2.7.4.6]
467948  DCTPP1; dCTP pyrophosphatase 1 [KO:K16904] [EC:3.6.1.12]
468345  CANT1; soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
469289  NT5C1A; cytosolic 5'-nucleotidase 1A [KO:K01081] [EC:3.1.3.5]
469296  CTPS1; CTP synthase 1 isoform X2 [KO:K01937] [EC:6.3.4.2]
470316  NT5C1B; cytosolic 5'-nucleotidase 1B isoform X4 [KO:K01081] [EC:3.1.3.5]
470338  CAD; multifunctional protein CAD isoform X2 [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
470484  NT5DC4; 5'-nucleotidase domain-containing protein 4 [KO:K01081] [EC:3.1.3.5]
470566  UPP2; uridine phosphorylase 2 isoform X2 [KO:K00757] [EC:2.4.2.3]
472343  NT5C3A; cytosolic 5'-nucleotidase 3A isoform X2 [KO:K24242]
472361  UPP1; uridine phosphorylase 1 isoform X1 [KO:K00757] [EC:2.4.2.3]
472832  RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X1 [KO:K10808] [EC:1.17.4.1]
736760  NT5C; 5'(3')-deoxyribonucleotidase, cytosolic type [KO:K01081] [EC:3.1.3.5]
736974  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 isoform X1 [KO:K01510] [EC:3.6.1.5]
739415  ASMTL; probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [KO:K25435]
739661  [KO:K24242]
740018  TYMS; thymidylate synthase [KO:K00560] [EC:2.1.1.45]
742176  TK1; thymidine kinase, cytosolic isoform X2 [KO:K00857] [EC:2.7.1.21]
743177  NT5C3B; 7-methylguanosine phosphate-specific 5'-nucleotidase isoform X1 [KO:K24242]
744046  CDA; cytidine deaminase [KO:K01489] [EC:3.5.4.5]
744320  DTYMK; thymidylate kinase isoform X1 [KO:K00943] [EC:2.7.4.9]
745004  UCK1; uridine-cytidine kinase 1 isoform X1 [KO:K00876] [EC:2.7.1.48]
746086  HDDC2; 5'-deoxynucleotidase HDDC2 isoform X5 [KO:K07023] [EC:3.1.3.89]
747532  UPB1; beta-ureidopropionase isoform X1 [KO:K01431] [EC:3.5.1.6]
748077  UCK2; uridine-cytidine kinase 2 isoform X1 [KO:K00876] [EC:2.7.1.48]
748497  AK9; adenylate kinase 9 isoform X3 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
Compound
C00015  UDP
C00039  DNA
C00046  RNA
C00055  CMP
C00063  CTP
C00064  L-Glutamine
C00075  UTP
C00086  Urea
C00099  beta-Alanine
C00105  UMP
C00106  Uracil
C00112  CDP
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00169  Carbamoyl phosphate
C00178  Thymine
C00214  Thymidine
C00222  3-Oxopropanoate
C00239  dCMP
C00295  Orotate
C00299  Uridine
C00337  (S)-Dihydroorotate
C00363  dTDP
C00364  dTMP
C00365  dUMP
C00380  Cytosine
C00383  Malonate
C00429  5,6-Dihydrouracil
C00438  N-Carbamoyl-L-aspartate
C00458  dCTP
C00459  dTTP
C00460  dUTP
C00475  Cytidine
C00526  Deoxyuridine
C00672  2-Deoxy-D-ribose 1-phosphate
C00705  dCDP
C00813  Barbiturate
C00881  Deoxycytidine
C00941  3',5'-Cyclic CMP
C01013  3-Hydroxypropanoate
C01103  Orotidine 5'-phosphate
C01168  Pseudouridine 5'-phosphate
C01205  (R)-3-Amino-2-methylpropanoate
C01346  dUDP
C01368  3'-UMP
C01563  Carbamate
C02067  Pseudouridine
C02170  Methylmalonate
C02354  2',3'-Cyclic CMP
C02355  2',3'-Cyclic UMP
C02376  5-Methylcytosine
C02642  3-Ureidopropionate
C03997  5-Hydroxymethyldeoxycytidylate
C05281  5-Methylbarbiturate
C05822  3'-CMP
C06198  P1,P4-Bis(5'-uridyl) tetraphosphate
C11038  2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039  2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607  3-Oxo-3-ureidopropanoate
C20231  (Z)-3-Ureidoacrylate peracid
C20249  (Z)-3-Peroxyaminoacrylate
C20253  Aminoacrylate
C20254  Ureidoacrylate
C20846  3-Oxo-3-ureidoisobutyrate
C21028  (R)-5,6-Dihydrothymine
C21029  (R)-3-Ureidoisobutyrate
C22509  3',5'-Cyclic UMP
Related
pathway
ptr00030  Pentose phosphate pathway
ptr00220  Arginine biosynthesis
ptr00250  Alanine, aspartate and glutamate metabolism
ptr00280  Valine, leucine and isoleucine degradation
ptr00410  beta-Alanine metabolism
KO pathway
ko00240   

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