KEGG   PATHWAY: rno00040
Entry
rno00040                    Pathway                                
Name
Pentose and glucuronate interconversions - Rattus norvegicus (rat)
Class
Metabolism; Carbohydrate metabolism
Pathway map
rno00040  Pentose and glucuronate interconversions
rno00040

Module
rno_M00014  Glucuronate pathway (uronate pathway) [PATH:rno00040]
rno_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:rno00040]
Organism
Rattus norvegicus (rat) [GN:rno]
Gene
24434  Gusb; beta-glucuronidase precursor [KO:K01195] [EC:3.2.1.31]
83504  Kl; klotho precursor [KO:K14756] [EC:3.2.1.31]
83808  Ugt2b35; UDP-glucuronosyltransferase 2B15 precursor [KO:K00699] [EC:2.4.1.17]
24862  Ugt2b; UDP-glucuronosyltransferase 2B2 precursor [KO:K00699] [EC:2.4.1.17]
63867  Ugt2a1; UDP-glucuronosyltransferase 2A1 precursor [KO:K00699] [EC:2.4.1.17]
574523  Ugt1a5; UDP-glucuronosyltransferase 1A5 precursor [KO:K00699] [EC:2.4.1.17]
301595  Ugt1a8; UDP-glucuronosyltransferase 1A8 precursor [KO:K00699] [EC:2.4.1.17]
24861  Ugt1a1; UDP-glucuronosyltransferase 1A1 precursor [KO:K00699] [EC:2.4.1.17]
113992  Ugt1a6; UDP-glucuronosyltransferase 1-6 precursor [KO:K00699] [EC:2.4.1.17]
289533  Ugt2a3; UDP-glucuronosyltransferase 2A3 precursor [KO:K00699] [EC:2.4.1.17]
266685  Ugt2b15; UDP-glucuronosyltransferase 2B17 precursor [KO:K00699] [EC:2.4.1.17]
29623  Ugt2b37; UDP-glucuronosyltransferase 2B37 precursor [KO:K00699] [EC:2.4.1.17]
286954  Ugt2b1; UDP-glucuronosyltransferase 2B1 precursor [KO:K00699] [EC:2.4.1.17]
396552  Ugt1a9; UDP glycosyltransferase 1 family, polypeptide A10 precursor [KO:K00699] [EC:2.4.1.17]
396551  Ugt1a3; UDP-glucuronosyltransferase 1A3 precursor [KO:K00699] [EC:2.4.1.17]
154516  Ugt1a7c; UDP-glucuronosyltransferase 1A7 precursor [KO:K00699] [EC:2.4.1.17]
396527  Ugt1a2; UDP-glucuronosyltransferase 1-2 precursor [KO:K00699] [EC:2.4.1.17]
305264  Ugt2b10; UDP-glucuronosyltransferase 2B10 precursor [KO:K00699] [EC:2.4.1.17]
286989  Ugt2b7; UDP-glucuronosyltransferase 2B7 precursor [KO:K00699] [EC:2.4.1.17]
501907  Ugt2b34l1; UDP-glucuronosyltransferase 2B31-like isoform X1 [KO:K00699] [EC:2.4.1.17]
134478834  UDP-glucuronosyltransferase 2B2 isoform X1 [KO:K00699] [EC:2.4.1.17]
83472  Ugdh; UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
289827  Ugp2; UTP--glucose-1-phosphate uridylyltransferase [KO:K00963] [EC:2.7.7.9]
78959  Akr1a1; aldo-keto reductase family 1 member A1 [KO:K00002] [EC:1.1.1.2]
290277  Cryl1; lambda-crystallin homolog [KO:K13247] [EC:1.1.1.45]
501157  Rpe; ribulose-phosphate 3-epimerase isoform 4 [KO:K01783] [EC:5.1.3.1]
316067  Xylb; xylulose kinase [KO:K00854] [EC:2.7.1.17]
24192  Akr1b1; aldo-keto reductase family 1 member B1 [KO:K00011] [EC:1.1.1.21]
116463  Akr1b7; aldo-keto reductase family 1 member B7 [KO:K00011] [EC:1.1.1.21]
286921  Akr1b8; aldose reductase-related protein 2 [KO:K00011] [EC:1.1.1.21]
296972  Akr1b10; aldo-keto reductase family 1 member B10 [KO:K00011] [EC:1.1.1.21]
171408  Dcxr; L-xylulose reductase [KO:K03331] [EC:1.1.1.10]
24788  Sord; sorbitol dehydrogenase [KO:K00008] [EC:1.1.1.14]
691002  Dhdh; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase isoform X4 [KO:K00078] [EC:1.3.1.20 1.1.1.179]
298250  Fggy; FGGY carbohydrate kinase domain-containing protein [KO:K00875] [EC:2.7.1.47]
493574  Crppa; D-ribitol-5-phosphate cytidylyltransferase [KO:K21031] [EC:2.7.7.40]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00167  UDP-glucuronate
C00181  D-Xylose
C00191  D-Glucuronate
C00199  D-Ribulose 5-phosphate
C00204  2-Dehydro-3-deoxy-D-gluconate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00266  Glycolaldehyde
C00309  D-Ribulose
C00310  D-Xylulose
C00312  L-Xylulose
C00333  D-Galacturonate
C00379  Xylitol
C00433  2,5-Dioxopentanoate
C00470  Pectate
C00474  Ribitol
C00476  D-Lyxose
C00502  D-Xylonate
C00508  L-Ribulose
C00514  D-Mannonate
C00532  L-Arabitol
C00558  D-Tagaturonate
C00618  3-Dehydro-L-gulonate
C00714  Pectin
C00789  CDP-ribitol
C00800  L-Gulonate
C00817  D-Altronate
C00905  D-Fructuronate
C01068  D-Ribitol 5-phosphate
C01101  L-Ribulose 5-phosphate
C01508  L-Lyxose
C01904  D-Arabitol
C02266  D-Xylonolactone
C02273  Digalacturonate
C02426  L-Glyceraldehyde
C02753  D-Xylono-1,4-lactone
C03033  beta-D-Glucuronoside
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C04053  5-Dehydro-4-deoxy-D-glucuronate
C04349  (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C06118  4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate
C06441  L-Xylulose 1-phosphate
C14899  3-Dehydro-L-gulonate 6-phosphate
C15930  L-Galactonate
C20680  2-Dehydro-3-deoxy-L-galactonate
C22337  D-Ribulose 1-phosphate
C22712  4-Deoxy-L-threo-hex-4-enopyranuronate
Reference
PMID:11741871
  Authors
Yew WS, Gerlt JA.
  Title
Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.
  Journal
J Bacteriol 184:302-6 (2002)
DOI:10.1128/JB.184.1.302-306.2002
Reference
PMID:15697206
  Authors
Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA
  Title
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
  Journal
Biochemistry 44:1807-15 (2005)
DOI:10.1021/bi047815v
Reference
PMID:10572115
  Authors
Yasueda H, Kawahara Y, Sugimoto S.
  Title
Bacillus subtilis yckG and yckF encode two key enzymes of the ribulose monophosphate pathway used by methylotrophs, and yckH is required for their expression.
  Journal
J Bacteriol 181:7154-60 (1999)
DOI:10.1128/JB.181.23.7154-7160.1999
Reference
PMID:10913097
  Authors
Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J
  Title
Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.
  Journal
J Bacteriol 182:4625-7 (2000)
DOI:10.1128/JB.182.16.4625-4627.2000
Reference
PMID:15901685
  Authors
Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N
  Title
The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.
  Journal
J Bacteriol 187:3636-42 (2005)
DOI:10.1128/JB.187.11.3636-3642.2005
Related
pathway
rno00010  Glycolysis / Gluconeogenesis
rno00020  Citrate cycle (TCA cycle)
rno00030  Pentose phosphate pathway
rno00052  Galactose metabolism
rno00053  Ascorbate and aldarate metabolism
rno00500  Starch and sucrose metabolism
rno00520  Amino sugar and nucleotide sugar metabolism
rno00561  Glycerolipid metabolism
rno00562  Inositol phosphate metabolism
rno00740  Riboflavin metabolism
KO pathway
ko00040   
LinkDB

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