KEGG   PATHWAY: rot00230
Entry
rot00230                    Pathway                                
Name
Purine metabolism - Roseivivax sp. THAF197b
Class
Metabolism; Nucleotide metabolism
Pathway map
rot00230  Purine metabolism
rot00230

Module
rot_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rot00230]
rot_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rot00230]
rot_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rot00230]
rot_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rot00230]
rot_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rot00230]
rot_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rot00230]
rot_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rot00230]
Other DBs
GO: 0006163 0042278
Organism
Roseivivax sp. THAF197b [GN:rot]
Gene
FIV09_06255  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
FIV09_03060  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
FIV09_09735  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
FIV09_15745  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
FIV09_07590  purF; Amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
FIV09_13635  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
FIV09_10340  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
FIV09_07690  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
FIV09_11045  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
FIV09_11040  purQ; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
FIV09_10345  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
FIV09_03650  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
FIV09_03655  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
FIV09_11050  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
FIV09_07825  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
FIV09_16880  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
FIV09_05960  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
FIV09_04705  yfkN2; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
FIV09_07570  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
FIV09_01465  deoD; Purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
FIV09_03700  yfiH; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
FIV09_11600  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
FIV09_11150  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
FIV09_08070  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
FIV09_17920  Non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
FIV09_10305  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
FIV09_15305  hcrC; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
FIV09_15310  ndhL; Nicotinate dehydrogenase large molybdopterin subunit [KO:K13482] [EC:1.17.1.4]
FIV09_10060  guaA2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
FIV09_05665  guaD1; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
FIV09_09180  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
FIV09_10275  nrdJ; Vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
FIV09_19975  nrdE2; Ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
FIV09_15245  nrdZ; Ribonucleoside-diphosphate reductase NrdZ [KO:K00525] [EC:1.17.4.1]
FIV09_19970  nrdF2; Ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
FIV09_09895  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
FIV09_17825  hypothetical protein [KO:K06952] [EC:3.1.3.89]
FIV09_16390  rsh; GTP pyrophosphokinase rsh [KO:K01139] [EC:2.7.6.5 3.1.7.2]
FIV09_11300  gppA2; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FIV09_10685  gppA1; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FIV09_07075  cyaA; Adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
FIV09_04040  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
FIV09_03055  add2; Aminodeoxyfutalosine deaminase [KO:K01488] [EC:3.5.4.4]
FIV09_01615  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
FIV09_03200  ade; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
FIV09_02005  yfkN1; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
FIV09_04205  hypothetical protein [KO:K09769] [EC:3.1.4.16]
FIV09_13820  adk2; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
FIV09_09640  adk1; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
FIV09_07970  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
FIV09_03675  sat_cysC; putative bifunctional SAT/APS kinase [KO:K00958] [EC:2.7.7.4]
FIV09_12710  pucM; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
FIV09_07055  Asp/Glu/Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
FIV09_12705  uao; Uric acid degradation bifunctional protein [KO:K16842] [EC:3.5.2.5]
FIV09_12695  hypothetical protein [KO:K14977] [EC:3.5.3.26]
FIV09_12700  allA; Ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
FIV09_12505  ureC1; Urease subunit alpha 1 [KO:K01428] [EC:3.5.1.5]
FIV09_12515  ureB; Urease subunit beta [KO:K01429] [EC:3.5.1.5]
FIV09_12520  ureA; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
FIV09_12575  ywrD2; Putative gamma-glutamyltransferase YwrD [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rot00030  Pentose phosphate pathway
rot00220  Arginine biosynthesis
rot00250  Alanine, aspartate and glutamate metabolism
rot00260  Glycine, serine and threonine metabolism
rot00340  Histidine metabolism
rot00630  Glyoxylate and dicarboxylate metabolism
rot00730  Thiamine metabolism
rot00740  Riboflavin metabolism
rot00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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