KEGG   PATHWAY: stt00230
Entry
stt00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Typhi Ty2
Class
Metabolism; Nucleotide metabolism
Pathway map
stt00230  Purine metabolism
stt00230

Module
stt_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:stt00230]
stt_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:stt00230]
stt_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:stt00230]
stt_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:stt00230]
stt_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:stt00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Typhi Ty2 [GN:stt]
Gene
t3106  conserved hypothetical protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
t4012  yrfE; putative NUDIX hydrolase [KO:K08312] [EC:3.6.1.-]
t4612  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
t2177  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
t1096  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
t0502  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
t3456  purD; phosphoribosylglycineamide synthetase [KO:K01945] [EC:6.3.4.13]
t0357  purN; phosphoribosylglycinamidine myltransferase [KO:K11175] [EC:2.1.2.2]
t0994  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
t0291  purL; phosphoribosylformylglycineamide synthetase [KO:K01952] [EC:6.3.5.3]
t0358  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
t2328  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
t2327  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
t0372  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
t1688  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
t3455  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
t2377  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
t2828  surE; stationary phase survival protein [KO:K03787] [EC:3.1.3.5 3.1.3.6]
t2194  nagD; NagD protein [KO:K02566] [EC:3.1.3.5]
t4010  yrfG; putative hydrolase [KO:K20881] [EC:3.1.3.-]
t2369  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
t0435  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
t4613  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
t2473  yaiE; conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
t2617  yfiH; conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
t0175  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
t0346  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
t0330  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
t3015  conserved hypothetical protein [KO:K01519] [EC:3.6.1.66]
t2533  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
t0347  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
t0420  putative amidotransferase [KO:K01951] [EC:6.3.5.2]
t0147  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
t3778  gmk; 5'guanylate kinase [KO:K00942] [EC:2.7.4.8]
t2704  nrdE; ribonucleoside-diphosphate reductase 2 alpha chain [KO:K00525] [EC:1.17.4.1]
t0587  nrdA; ribonucleoside-diphosphate reductase 1 alpha chain [KO:K00525] [EC:1.17.4.1]
t2705  nrdF; ribonucleoside-diphosphate reductase 2 beta chain [KO:K00526] [EC:1.17.4.1]
t0586  nrdB; ribonucleoside-diphosphate reductase 1 beta chain [KO:K00526] [EC:1.17.4.1]
t4486  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
t0209  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
t0532  putative oxetanocin A biosynthetic enzyme [KO:K08722] [EC:3.1.3.89]
t3776  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
t3383  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
t0355  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
t2865  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
t3358  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
t4417  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
t1331  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
t0868  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
t2877  ygdH; conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
t4456  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
t2372  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
t2855  conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
t3104  icc; conserved hypothetical protein [KO:K03651] [EC:3.1.4.53]
t0091  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
t2834  cysC; adenosine 5-phosphosulfate kinase [KO:K00860] [EC:2.7.1.25]
t2835  cysN; ATP sulfurylase subunit [KO:K00956] [EC:2.7.7.4]
t2836  cysD; ATP sulfurylase subunit [KO:K00957] [EC:2.7.7.4]
t1822  putative exported protein [KO:K07127] [EC:3.5.2.17]
t2338  allB; putative allantoinase [KO:K01466] [EC:3.5.2.5]
t2334  allC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
t2335  conserved hypothetical protein [KO:K14977] [EC:3.5.3.26]
t2333  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
t2329  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
t4500  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
stt00030  Pentose phosphate pathway
stt00220  Arginine biosynthesis
stt00250  Alanine, aspartate and glutamate metabolism
stt00260  Glycine, serine and threonine metabolism
stt00340  Histidine metabolism
stt00630  Glyoxylate and dicarboxylate metabolism
stt00730  Thiamine metabolism
stt00740  Riboflavin metabolism
stt00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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