KEGG   PATHWAY: tros00564
Entry
tros00564                   Pathway                                
Name
Glycerophospholipid metabolism - Triplophysa rosa
Class
Metabolism; Lipid metabolism
Pathway map
tros00564  Glycerophospholipid metabolism
tros00564

Module
tros_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:tros00564]
tros_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:tros00564]
tros_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:tros00564]
Other DBs
GO: 0006650
Organism
Triplophysa rosa [GN:tros]
Gene
130558070  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
130566897  gpd1c; glycerol-3-phosphate dehydrogenase 1c [KO:K00006] [EC:1.1.1.8]
130548434  gpd1b; glycerol-3-phosphate dehydrogenase 1b [KO:K00006] [EC:1.1.1.8]
130567754  gpd1a; glycerol-3-phosphate dehydrogenase 1a [KO:K00006] [EC:1.1.1.8]
130556943  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
130567638  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
130569155  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
130570220  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
130545827  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
130568372  glycerol-3-phosphate acyltransferase 4-like [KO:K13506] [EC:2.3.1.15]
130550684  agpat9l; glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
130570046  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
130558835  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130553288  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130558888  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
130550895  lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
130558246  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130559950  mboat2a; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130566287  mboat2b; lysophospholipid acyltransferase 2b isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130566312  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
130566393  gnpat2; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
130569377  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
130545771  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
130553793  plpp2a; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
130553878  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
130565614  plpp3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
130561850  ppap2d; phosphatidic acid phosphatase type 2D [KO:K01080] [EC:3.1.3.4]
130549252  plpp2b; phospholipid phosphatase 2b [KO:K01080] [EC:3.1.3.4]
130568043  phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
130558166  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
130559848  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
130566214  lpin1b; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
130555130  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
130556714  zgc:123305 [KO:K15728] [EC:3.1.3.4]
130546555  plpp5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130550904  phospholipid phosphatase 4-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130563665  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
130552140  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
130564585  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
130545578  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
130565278  diacylglycerol kinase epsilon-like [KO:K00901] [EC:2.7.1.107]
130572044  dgkaa; diacylglycerol kinase, alpha a isoform X1 [KO:K00901] [EC:2.7.1.107]
130547667  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
130556098  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
130556192  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
130562058  dgkza; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
130557046  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
130547517  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
130567793  cept1a; choline/ethanolaminephosphotransferase 1a isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
130549090  cept1b; choline/ethanolaminephosphotransferase 1b [KO:K13644] [EC:2.7.8.1 2.7.8.2]
130569600  sphingomyelin synthase-related protein 1-like [KO:K22697] [EC:3.1.4.62]
130560786  samd8; sphingomyelin synthase-related protein 1 isoform X1 [KO:K22697] [EC:3.1.4.62]
130552708  sgms2a; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
130560576  sgms1a; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
130568992  sgms1b; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
130569659  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
130547221  pld1b; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
130554710  pld1a; phospholipase D1a [KO:K01115] [EC:3.1.4.4]
130555494  si:ch211-168k14.2; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
130560237  5'-3' exonuclease PLD4 isoform X1 [KO:K16860] [EC:3.1.4.4]
130562838  pld3; 5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
130551485  lcat; LOW QUALITY PROTEIN: phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
130552527  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130545937  pla2g3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130559171  pla2g12b; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
130565087  proca1; uncharacterized protein proca1 [KO:K01047] [EC:3.1.1.4]
130546489  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
130561469  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130568264  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
130568265  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
130564038  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
130545404  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
130545426  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
130553771  pla2g4aa; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
130559815  uncharacterized protein LOC130559815 [KO:K16342] [EC:3.1.1.4]
130566336  pla2g4ab; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
130560819  pla2g4f.2; cytosolic phospholipase A2 delta isoform X1 [KO:K16342] [EC:3.1.1.4]
130549101  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
130566184  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130560522  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130563964  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130554376  phospholipase A and acyltransferase 4-like isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130551152  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130563348  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130557649  lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130567285  lpcat1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130562867  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130556500  lysophospholipid acyltransferase LPCAT4-like [KO:K13512] [EC:2.3.1.23 2.3.1.-]
130558466  lpcat3; lysophospholipid acyltransferase 5 isoform X1 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
130559578  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
130551487  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
130566726  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
130570152  pnpla7a; patatin-like phospholipase domain-containing protein 7a [KO:K14676] [EC:3.1.1.5]
130545766  pnpla7b; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
130552844  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
130565577  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
130559189  chata; LOW QUALITY PROTEIN: choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
130568931  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
130553499  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
130562747  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
130562834  chka; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
130562050  phospho1; probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
130570617  pcyt1bb; phosphate cytidylyltransferase 1B, choline b [KO:K00968] [EC:2.7.7.15]
130554303  pcyt1aa; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
130546998  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
130563147  pcyt1ab; phosphate cytidylyltransferase 1A, choline b isoform X1 [KO:K00968] [EC:2.7.7.15]
130572059  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
130552265  zgc:113516; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
130571473  etnk2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
130547702  etnk1; ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
130548704  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
130563378  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
130559620  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
130569351  phosphatidylethanolamine N-methyltransferase-like [KO:K00551] [EC:2.1.1.17 2.1.1.71]
130569560  phosphatidylethanolamine N-methyltransferase-like [KO:K00551] [EC:2.1.1.17 2.1.1.71]
130565345  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
130566776  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
130555873  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
130558154  ptdss1a; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
130567339  ptdss1b; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
130551680  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
130567675  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
130569120  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
130560792  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
130549482  tafazzin-like isoform X1 [KO:K13511] [EC:2.3.1.-]
130549920  tafazzin-like isoform X1 [KO:K13511] [EC:2.3.1.-]
130565596  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
130562055  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
130557817  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
tros00010  Glycolysis / Gluconeogenesis
tros00260  Glycine, serine and threonine metabolism
tros00561  Glycerolipid metabolism
tros00562  Inositol phosphate metabolism
tros00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
tros00565  Ether lipid metabolism
tros00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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