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ENTRY	nt06504
Name	Base excision repair
Category	Pathway view; Replication and repair
Pathway	hsa03410 Base excision repair
Display	drug-target relation   disease type

N01433    glycosylase → APEX = POLB     HIGM5 UNG*     GC/FAP2 MUTYH*     TPDS2 MBD4*   N01434    glycosylase → APEX = POLB+XRCC1 = PARP,PARG,ADPRS     RCC OGG1*     FAP3 NTHL1*     SCAR26         XRCC1*     CONDSIAS             ADPRS*   N01435    glycosylase → TDP1+PNKP = POLB+XRCC1 = PARP     AOA4     PNKP*     SCAN1     TDP1*   N01436    POLB = (POLD,POLE) = PCNA = RFC → PCNA+FEN1 → PCNA+LIG1     PPAP/MDPL     POLD1*     IMD122     POLD3*     PPAP/IMAGE/FILS     POLE*     CANVAS             RFC1*     LIG1D                     LIG1*   N01437    POLB = XRCC1 = APTX → XRCC1+LIG3     AOA1         APTX*   N01438    POLG → LIG3     MNGIE/MTDPS4/PEOA1 POLG*     MTDPS16/PEOA4 POLG2*     MNGIE     LIG3*

		Disease name	Disease category
HIGM5	H00086	Immunodeficiency with hyper-IgM	Immune system disease
GC/FAP2	H00018	Gastric cancer	Cancer
	H01025	Familial adenomatous polyposis	Neoplasm
TPDS2	H02624	Tumor predisposition syndrome	Cancer
RCC	H00021	Renal cell carcinoma	Cancer
FAP3	H01025	Familial adenomatous polyposis	Neoplasm
SCAR26	H01891	Autosomal recessive spinocerebellar ataxias	Neurodegenerative disease
CONDSIAS	H02572	Neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures	Nervous system disease
AOA4	H00848	Ataxia with ocular apraxia	Nervous system disease
SCAN1	H02573	Autosomal recessive spinocerebellar ataxias with axonal neuropathy	Neurodegenerative disease
PPAP/MDPL	H02568	Polymerase proofreading-associated polyposis	Cancer
	H01623	MDPL syndrome	Congenital malformation
IMD122	H00091	T-B+Severe combined immunodeficiency	Primary immunodeficiency
PPAP/IMAGE/FILS	H02568	Polymerase proofreading-associated polyposis	Cancer
	H02369	IMAGE-I syndrome	Congenital malformation
	H02370	FILS syndrome	Congenital malformation
CANVAS	H02366	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome	Nervous system disease
LIG1D	H00094	Immunodeficiency associated with DNA repair defects	Primary immunodeficiency
AOA1	H00848	Ataxia with ocular apraxia	Nervous system disease
MNGIE/MTDPS4/PEOA1	H01390	Mitochondrial neurogastrointestinal encephalomyopathy	Inherited metabolic disorder, Mitochondrial disease
	H00469	Mitochondrial DNA depletion syndrome	Inherited metabolic disorder, Mitochondrial disease
	H01118	Progressive external ophthalmoplegia	Nervous system disease
MTDPS16/PEOA4	H00469	Mitochondrial DNA depletion syndrome	Inherited metabolic disorder, Mitochondrial disease
	H01118	Progressive external ophthalmoplegia	Nervous system disease
MNGIE	H01390	Mitochondrial neurogastrointestinal encephalomyopathy	Inherited metabolic disorder, Mitochondrial disease