KEGG   PATHWAY: bcl00230
Entry
bcl00230                    Pathway                                
Name
Purine metabolism - Alkalihalobacillus clausii
Class
Metabolism; Nucleotide metabolism
Pathway map
bcl00230  Purine metabolism
bcl00230

Module
bcl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bcl00230]
bcl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bcl00230]
bcl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bcl00230]
bcl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bcl00230]
bcl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bcl00230]
Other DBs
GO: 0006163 0042278
Organism
Alkalihalobacillus clausii [GN:bcl]
Gene
ABC1778  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ABC1783  drm; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ABC0678  conserved hypothetical protein [KO:K01839] [EC:5.4.2.7]
ABC1499  phosphomannomutase [KO:K01835] [EC:5.4.2.2]
ABC3150  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ABC0079  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ABC1031  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ABC1035  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ABC1033  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ABC1030  purL; phosphoribosylformylglycinamidine synthase component II [KO:K23269] [EC:6.3.5.3]
ABC1028  purS; phosphorybosylformylglycinamidine synthase PurS component [KO:K23264] [EC:6.3.5.3]
ABC1029  purQ; phosphoribosylformylglycinamidine synthase component I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
ABC1032  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ABC1025  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
ABC1024  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
ABC1027  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ABC2086  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ABC1026  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ABC1034  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ABC1569  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ABC2957  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
ABC0966  nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ABC3722  pupG; purine nucleoside phosphorylase I [KO:K03783] [EC:2.4.2.1]
ABC4021  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ABC2348  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ABC3998  inosine-uridine preferring nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
ABC3550  inosine-uridine preferring nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
ABC0105  hprT; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ABC0011  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ABC1890  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ABC2775  conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
ABC2651  xanthosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
ABC1443  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
ABC3740  pucA; xanthine dehydrogenase subunit E [KO:K00087] [EC:1.17.1.4]
ABC3742  pucC; xanthine dehydrogenase subunit C [KO:K00087] [EC:1.17.1.4]
ABC3743  pucD; xanthine dehydrogenase subunit B [KO:K00087] [EC:1.17.1.4]
ABC3744  pucE; xanthine dehydrogenase subunit A [KO:K00087] [EC:1.17.1.4]
ABC3741  pucB; xanthine dehydrogenase subunit D [KO:K00087] [EC:1.17.1.4]
ABC0936  guaA; GMP synthetase [KO:K01951] [EC:6.3.5.2]
ABC3216  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
ABC3819  gde; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ABC2322  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ABC3108  nrdE; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
ABC3109  nrdF; ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
ABC2889  dgk; deoxypurine kinase [KO:K15518] [EC:2.7.1.113]
ABC1570  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ABC2520  GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
ABC2538  conserved hypothetical protein [KO:K07816] [EC:2.7.6.5]
ABC4100  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
ABC2890  dck; deoxypurine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
ABC3209  adenine deaminase [KO:K01486] [EC:3.5.4.2]
ABC1075  adenine deaminase [KO:K01486] [EC:3.5.4.2]
ABC1077  adeC; adenine deaminase [KO:K01486] [EC:3.5.4.2]
ABC2193  conserved hypothetical protein [KO:K09769] [EC:3.1.4.16]
ABC0171  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
ABC0614  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
ABC0612  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
ABC3735  uricase [KO:K16838] [EC:1.7.3.3 4.1.1.97]
ABC3734  pucM; transthyretin-like protein [KO:K07127] [EC:3.5.2.17]
ABC3732  pucH; allantoinase [KO:K01466] [EC:3.5.2.5]
ABC3738  pucH; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
ABC3483  N-carbamoyl-L-amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
ABC3739  pucG; aminotransferase [KO:K00839] [EC:2.6.1.112]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bcl00030  Pentose phosphate pathway
bcl00220  Arginine biosynthesis
bcl00250  Alanine, aspartate and glutamate metabolism
bcl00260  Glycine, serine and threonine metabolism
bcl00340  Histidine metabolism
bcl00630  Glyoxylate and dicarboxylate metabolism
bcl00730  Thiamine metabolism
bcl00740  Riboflavin metabolism
bcl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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