KEGG   PATHWAY: bmj00230
Entry
bmj00230                    Pathway                                
Name
Purine metabolism - Burkholderia multivorans ATCC 17616 (Tohoku)
Class
Metabolism; Nucleotide metabolism
Pathway map
bmj00230  Purine metabolism
bmj00230

Module
bmj_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bmj00230]
bmj_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bmj00230]
bmj_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bmj00230]
bmj_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bmj00230]
bmj_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bmj00230]
bmj_M00546  Purine degradation, xanthine => urea [PATH:bmj00230]
bmj_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bmj00230]
bmj_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bmj00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia multivorans ATCC 17616 (Tohoku) [GN:bmj]
Gene
BMULJ_02220  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BMULJ_00739  manB; phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BMULJ_05600  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BMULJ_02747  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BMULJ_03896  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BMULJ_02281  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
BMULJ_02475  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BMULJ_02306  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BMULJ_01883  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BMULJ_00614  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BMULJ_02585  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
BMULJ_02586  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
BMULJ_02587  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BMULJ_00520  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BMULJ_00545  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BMULJ_02728  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BMULJ_01793  surE; 5'-nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BMULJ_03287  surE; 5'-nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BMULJ_04400  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
BMULJ_01760  yfiH; conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BMULJ_00443  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BMULJ_01962  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
BMULJ_01783  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BMULJ_00832  ham1; putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BMULJ_00686  xdhA; xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
BMULJ_00687  xdhA; xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
BMULJ_00287  coxL; aerobic-type carbon monoxide dehydrogenase large subunit [KO:K11177] [EC:1.17.1.4]
BMULJ_00286  coxM; aerobic-type carbon monoxide dehydrogenase medium subunit [KO:K11178] [EC:1.17.1.4]
BMULJ_00285  carbon-monoxide dehydrogenase small subunit [KO:K13483]
BMULJ_04305  4-hydroxybenzoyl-CoA reductase [KO:K13483]
BMULJ_03194  guaA; glutamine-hydrolysing GMP synthase [KO:K01951] [EC:6.3.5.2]
BMULJ_01960  guaA; glutamine-hydrolysing GMP synthase [KO:K01951] [EC:6.3.5.2]
BMULJ_00864  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BMULJ_00835  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BMULJ_05649  nrdA; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
BMULJ_00448  nrdA; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
BMULJ_00449  nrdB; ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
BMULJ_02957  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
BMULJ_06164  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BMULJ_00837  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BMULJ_01231  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMULJ_01459  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
BMULJ_05365  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BMULJ_01769  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BMULJ_00453  adk; adenosine kinase [KO:K00856] [EC:2.7.1.20]
BMULJ_03639  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BMULJ_00865  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BMULJ_02852  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BMULJ_02512  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMULJ_01166  icc; Icc protein [KO:K03651] [EC:3.1.4.53]
BMULJ_00720  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BMULJ_02435  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
BMULJ_02436  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
BMULJ_03413  predicted flavoprotein [KO:K22879] [EC:1.14.13.113]
BMULJ_01935  putative purine catabolism-related protein [KO:K07127] [EC:3.5.2.17]
BMULJ_01939  conserved hypothetical protein [KO:K13485] [EC:4.1.1.97]
BMULJ_01941  hyuE; hydantoin racemase [KO:K16841] [EC:5.1.99.3]
BMULJ_01940  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
BMULJ_01938  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BMULJ_00498  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BMULJ_05196  conserved hypothetical protein [KO:K14977] [EC:3.5.3.26]
BMULJ_00499  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BMULJ_01937  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BMULJ_05242  putative fumarylacetoacetate hydrolase [KO:K16856] [EC:4.3.2.3]
BMULJ_00746  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
BMULJ_00747  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
BMULJ_00748  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bmj00030  Pentose phosphate pathway
bmj00220  Arginine biosynthesis
bmj00250  Alanine, aspartate and glutamate metabolism
bmj00260  Glycine, serine and threonine metabolism
bmj00340  Histidine metabolism
bmj00630  Glyoxylate and dicarboxylate metabolism
bmj00730  Thiamine metabolism
bmj00740  Riboflavin metabolism
bmj00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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