KEGG   PATHWAY: cery00830
Entry
cery00830                   Pathway                                
Name
Retinol metabolism - Chanodichthys erythropterus (predatory carp)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
cery00830  Retinol metabolism
cery00830

Other DBs
GO: 0006776
Organism
Chanodichthys erythropterus (predatory carp) [GN:cery]
Gene
137002887  sdr16c5a; short chain dehydrogenase/reductase family 16C, member 5a [KO:K15734] [EC:1.1.1.105]
137002944  rdh10b; retinol dehydrogenase 10-B [KO:K11151] [EC:1.1.1.-]
137003257  si:dkey-94e7.2; retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
137003303  rpe65a; retinoid isomerohydrolase [KO:K11158] [EC:3.1.1.64 5.3.3.22]
137006593  cyp26c1; cytochrome P450 26C1 [KO:K12665] [EC:1.14.14.-]
137007651  cyp26a1; cytochrome P450 26A1 [KO:K07437] [EC:1.14.14.-]
137007968  si:ch1073-13h15.3; inactive all-trans-retinol 13,14-reductase [KO:K09516] [EC:1.3.99.23]
137009232  dhrs3a; short-chain dehydrogenase/reductase 3a isoform X1 [KO:K11146] [EC:1.1.1.300]
137010539  zgc:109982; retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
137011390  rdh20; retinol dehydrogenase 10 [KO:K11151] [EC:1.1.1.-]
137011437  cyp27c1; cytochrome P450 27C1 [KO:K17951] [EC:1.14.19.53]
137012543  [KO:K07424] [EC:1.14.14.1]
137012551  [KO:K07424] [EC:1.14.14.1]
137012944  rdh8a; retinol dehydrogenase 8a isoform X1 [KO:K11150] [EC:1.1.1.-]
137012949  zmp:0000001048; retinol dehydrogenase 8 isoform X1 [KO:K11150] [EC:1.1.1.-]
137013468  rdh10a; retinol dehydrogenase 10-A [KO:K11151] [EC:1.1.1.-]
137013963  rdh12l; retinol dehydrogenase 12, like [KO:K11153] [EC:1.1.1.300]
137014340  zgc:112332; retinol dehydrogenase 12 isoform X1 [KO:K11153] [EC:1.1.1.300]
137014430  si:dkey-73n8.3; retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
137014788  [KO:K00699] [EC:2.4.1.17]
137014965  adh5l; alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
137015033  zgc:77938; alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
137015247  [KO:K00699] [EC:2.4.1.17]
137015248  [KO:K00699] [EC:2.4.1.17]
137015315  [KO:K00699] [EC:2.4.1.17]
137015317  ugt5a1; UDP glucuronosyltransferase 5 family, polypeptide A1 [KO:K00699] [EC:2.4.1.17]
137017130  adh5; alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
137017729  [KO:K09516] [EC:1.3.99.23]
137017785  [KO:K07424] [EC:1.14.14.1]
137017787  [KO:K07424] [EC:1.14.14.1]
137019130  si:dkey-221h15.4; epidermal retinol dehydrogenase 2 isoform X1 [KO:K15734] [EC:1.1.1.105]
137020355  adh8b; LOW QUALITY PROTEIN: alcohol dehydrogenase 8b [KO:K00121] [EC:1.1.1.284 1.1.1.1]
137020356  [KO:K00121] [EC:1.1.1.284 1.1.1.1]
137020661  rdh12; retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
137021052  dhrs3b; short-chain dehydrogenase/reductase 3b [KO:K11146] [EC:1.1.1.300]
137021280  [KO:K11151] [EC:1.1.1.-]
137021485  [KO:K00699] [EC:2.4.1.17]
137021488  [KO:K00699] [EC:2.4.1.17]
137021489  [KO:K00699] [EC:2.4.1.17]
137023485  ugt5f1; UDP glucuronosyltransferase 5 family, polypeptide F1 [KO:K00699] [EC:2.4.1.17]
137026297  [KO:K11158] [EC:3.1.1.64 5.3.3.22]
137026913  ugt5e1; LOW QUALITY PROTEIN: UDP glucuronosyltransferase 5 family, polypeptide E1 [KO:K00699] [EC:2.4.1.17]
137026985  dgat1b; diacylglycerol O-acyltransferase 1b [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
137027666  aox6; aldehyde oxidase 6 isoform X1 [KO:K00157] [EC:1.2.3.1]
137027877  rdh5; retinol dehydrogenase 5 [KO:K00061] [EC:1.1.1.315]
137028369  ugt5g2; UDP glucuronosyltransferase 5 family, polypeptide G2 [KO:K00699] [EC:2.4.1.17]
137029067  aox5; aldehyde oxidase 5 [KO:K00157] [EC:1.2.3.1]
137029675  ugt5d1; UDP glucuronosyltransferase 5 family, polypeptide D1 [KO:K00699] [EC:2.4.1.17]
137029835  aldh1a2; retinal dehydrogenase 2 [KO:K07249] [EC:1.2.1.36]
137029841  si:ch211-107o10.3; retinol dehydrogenase 11 [KO:K11153] [EC:1.1.1.300]
137030088  bco1l; beta,beta-carotene 15,15'-dioxygenase isoform X1 [KO:K00515] [EC:1.13.11.63]
137030126  sdr16c5b; epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
137030181  aldh1a3; aldehyde dehydrogenase family 1 member A3 [KO:K07249] [EC:1.2.1.36]
137030260  dhrs4; dehydrogenase/reductase SDR family member 4 isoform X1 [KO:K11147] [EC:1.1.-.-]
137030929  bco1; beta,beta-carotene 15,15'-dioxygenase [KO:K00515] [EC:1.13.11.63]
137031023  cyp26b1; cytochrome P450 26B1 [KO:K12664] [EC:1.14.14.-]
137031885  pnpla4; patatin-like phospholipase domain-containing protein 4 isoform X1 [KO:K11157] [EC:3.1.1.-]
137032020  cyp3a65; cytochrome P450, family 3, subfamily A, polypeptide 65 [KO:K07424] [EC:1.14.14.1]
137032493  rdh8b; retinol dehydrogenase 8b [KO:K11150] [EC:1.1.1.-]
137032495  [KO:K11150] [EC:1.1.1.-]
137032635  lrata; lecithin retinol acyltransferase a [KO:K00678] [EC:2.3.1.135]
137032662  lratb.2; lecithin retinol acyltransferase b, tandem duplicate 2 [KO:K00678] [EC:2.3.1.135]
137032840  si:dkey-30k22.5; lecithin retinol acyltransferase family protein [KO:K00678] [EC:2.3.1.135]
137032931  si:dkey-23o4.6; retinol dehydrogenase 13 isoform X1 [KO:K11153] [EC:1.1.1.300]
137033108  [KO:K00699] [EC:2.4.1.17]
137033617  [KO:K00699] [EC:2.4.1.17]
137033827  [KO:K00699] [EC:2.4.1.17]
137033828  [KO:K00699] [EC:2.4.1.17]
137034124  [KO:K00699] [EC:2.4.1.17]
137035083  [KO:K00699] [EC:2.4.1.17]
137035575  [KO:K00699] [EC:2.4.1.17]
137035590  [KO:K00699] [EC:2.4.1.17]
137036043  [KO:K09516] [EC:1.3.99.23]
137036044  [KO:K09516] [EC:1.3.99.23]
137036249  [KO:K00699] [EC:2.4.1.17]
137037304  zgc:153441; retinol-DH_like_SDR_c domain-containing protein [KO:K11153] [EC:1.1.1.300]
137037399  dgat1a; diacylglycerol O-acyltransferase 1a [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   

DBGET integrated database retrieval system