KEGG   PATHWAY: cfus00230
Entry
cfus00230                   Pathway                                
Name
Purine metabolism - Cystobacter fuscus
Class
Metabolism; Nucleotide metabolism
Pathway map
cfus00230  Purine metabolism
cfus00230

Module
cfus_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cfus00230]
cfus_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cfus00230]
cfus_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cfus00230]
cfus_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cfus00230]
cfus_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cfus00230]
cfus_M00546  Purine degradation, xanthine => urea [PATH:cfus00230]
cfus_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cfus00230]
cfus_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cfus00230]
Other DBs
GO: 0006163 0042278
Organism
Cystobacter fuscus [GN:cfus]
Gene
CYFUS_003007  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CYFUS_008118  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CYFUS_007350  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
CYFUS_009774  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CYFUS_008996  phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
CYFUS_006893  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CYFUS_000458  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CYFUS_001459  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CYFUS_003416  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CYFUS_003229  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CYFUS_006316  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CYFUS_003230  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CYFUS_002813  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
CYFUS_002814  phosphoribosylaminoimidazole carboxylase [KO:K01588] [EC:5.4.99.18]
CYFUS_007718  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CYFUS_007719  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CYFUS_003414  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CYFUS_007137  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CYFUS_009233  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CYFUS_007112  multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CYFUS_008843  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CYFUS_009672  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
CYFUS_005349  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
CYFUS_003773  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
CYFUS_005671  5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
CYFUS_007142  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
CYFUS_004396  stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CYFUS_008212  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
CYFUS_006455  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CYFUS_006888  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CYFUS_006166  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CYFUS_004562  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CYFUS_002824  hypothetical protein [KO:K01529] [EC:3.6.1.73]
CYFUS_007306  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CYFUS_002356  xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
CYFUS_002357  Xanthine dehydrogenase, molybdenum binding subunit [KO:K13482] [EC:1.17.1.4]
CYFUS_004798  aromatic aldehyde oxidoreductase molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
CYFUS_007083  aromatic aldehyde oxidoreductase molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
CYFUS_007603  Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR [KO:K11177] [EC:1.17.1.4]
CYFUS_005215  aromatic aldehyde oxidoreductase molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
CYFUS_007203  oxidoreductase [KO:K11177] [EC:1.17.1.4]
CYFUS_001830  aromatic aldehyde oxidoreductase molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
CYFUS_004123  aromatic aldehyde oxidoreductase molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
CYFUS_004799  aromatic aldehyde oxidoreductase FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
CYFUS_005214  aromatic aldehyde oxidoreductase FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
CYFUS_007204  aromatic aldehyde oxidoreductase FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
CYFUS_001831  aromatic aldehyde oxidoreductase FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
CYFUS_004124  aromatic aldehyde oxidoreductase FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
CYFUS_004800  aromatic aldehyde oxidoreductase [KO:K13483]
CYFUS_005213  Periplasmic aromatic aldehyde oxidoreductase, iron-sulfur subunit YagT [KO:K13483]
CYFUS_007202  oxidoreductase [KO:K13483]
CYFUS_001832  aromatic aldehyde oxidoreductase iron-sulfur subunit [KO:K13483]
CYFUS_004125  aromatic aldehyde oxidoreductase iron-sulfur subunit [KO:K13483]
CYFUS_009048  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
CYFUS_005070  GMP synthetase [KO:K01951] [EC:6.3.5.2]
CYFUS_007851  GMP synthase [KO:K01951] [EC:6.3.5.2]
CYFUS_005031  GMP synthase [KO:K01951] [EC:6.3.5.2]
CYFUS_006167  hypothetical protein [KO:K01487] [EC:3.5.4.3]
CYFUS_003547  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CYFUS_006565  ribonucleotide reductase of class II (coenzyme B12-dependent) [KO:K00525] [EC:1.17.4.1]
CYFUS_002032  ribonucleotide reductase of class Ia (aerobic), subunit alpha [KO:K00525] [EC:1.17.4.1]
CYFUS_002031  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
CYFUS_002472  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CYFUS_003619  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CYFUS_008727  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CYFUS_004332  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CYFUS_008016  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CYFUS_002480  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_005981  cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_005730  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_002733  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_005376  cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_009716  cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_003251  guanylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_003258  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_003767  hypothetical protein [KO:K01768] [EC:4.6.1.1]
CYFUS_001166  guanylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_009123  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CYFUS_009170  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CYFUS_002949  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CYFUS_002921  deoxyadenosine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
CYFUS_004218  deoxyadenosine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
CYFUS_006385  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CYFUS_002215  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CYFUS_008210  metallophosphatase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
CYFUS_006474  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
CYFUS_004207  adenylate kinase [KO:K00939] [EC:2.7.4.3]
CYFUS_003513  Nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
CYFUS_003453  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
CYFUS_005025  hypothetical protein [KO:K03651] [EC:3.1.4.53]
CYFUS_007269  phosphorylase [KO:K00988] [EC:2.7.7.5 2.7.7.53]
CYFUS_003919  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CYFUS_006095  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CYFUS_006199  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CYFUS_006200  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
CYFUS_009293  hypothetical protein [KO:K22879] [EC:1.14.13.113]
CYFUS_009297  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
CYFUS_009296  hypothetical protein [KO:K16840] [EC:4.1.1.97]
CYFUS_009294  allantoinase [KO:K01466] [EC:3.5.2.5]
CYFUS_009295  allantoicase [KO:K01477] [EC:3.5.3.4]
CYFUS_000756  hypothetical protein [KO:K01483] [EC:4.3.2.3]
CYFUS_009076  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CYFUS_009077  urease subunit beta [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cfus00030  Pentose phosphate pathway
cfus00220  Arginine biosynthesis
cfus00250  Alanine, aspartate and glutamate metabolism
cfus00260  Glycine, serine and threonine metabolism
cfus00340  Histidine metabolism
cfus00630  Glyoxylate and dicarboxylate metabolism
cfus00730  Thiamine metabolism
cfus00740  Riboflavin metabolism
cfus00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system